Date published: 2026-3-7

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RNA Polymerase Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of RNA Polymerase monoclonal antibodies for various research applications. RNA Polymerase monoclonal antibodies excel in techniques such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). RNA polymerases are essential enzymes responsible for synthesizing RNA from a DNA template, playing a central role in gene expression and regulation. RNA polymerases drive the transcription process, which is fundamental for cellular function and development. Understanding RNA polymerase activity and regulation provides key insights into various biological processes and disease mechanisms. RNA polymerase research advances knowledge in areas such as gene regulation, cellular development, and disease progression. Investigating RNA polymerase function helps illuminate potential therapeutic targets for various medical conditions. RNA polymerase studies contribute to breakthroughs in understanding cancer, viral infections, and genetic disorders. Santa Cruz Biotechnology monoclonal antibodies for RNA Polymerase research support scientists worldwide in advancing molecular biology understanding and developing new therapeutic strategies.

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RNA Polymerase Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Pol I/II/III RPB6 Antibody (B6-1)

sc-21751mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
7
(3)

Pol I/II/III RPB8 Antibody (B-2)

sc-398512mouse IgG1 κFL (h)WB, IP, IF, ELISAm, r, h
1
(1)

Pol I/II/III RPB8 Antibody (B8-1)

sc-21752mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
4
(2)

Pol I/II/III RPB8 Antibody (SP-75)

sc-134422mouse IgG1 κ1-151 (h)WB, IP, ELISAm, r, h

new

(2)

Pol II Antibody (CTD4H8)

sc-47701mouse IgG1 κSer-5 (h)WB, IP, IF, IHC(P)m, r, h
112
(28)

Pol II Antibody (F-12)

sc-55492mouse IgG2b κ1-224 (h)WB, IP, IF, IHC(P), ELISAm, r, h
59
(9)

Pol II Antibody (8WG16)

sc-56767mouse IgG2a κ(wheat germ)WB, IP, IFm, r, h, Xenopus, C. elegans, yeast, wheat germ and bovine
103
(14)

Pol II Antibody (A-10)

sc-17798mouse IgG2b κ1-224 (h)WB, IP, IF, ELISAm, r, h
48
(12)

Pol II Antibody (3WG2)

sc-21750mouse IgM κconserved heptapeptideWB, IPm, r, h
5
(2)

Pol II Antibody (mara-3)

sc-65884mouse IgM κC-Terminal (yeast)WB, IPm, r, h
1
(1)

Pol II Antibody (1.BB.61)

sc-71917mouse IgG2a κ(wheat germ)WB, IP, IFm, r, h, Xenopus, C. elegans, yeast, wheat germ and bovine
2
(1)

Pol II RPB6 Antibody (E-8)

sc-271309mouse IgG1 κFL (h)WB, IP, IF, ELISAm, r, h
2
(2)

Pol III RPC32 Antibody (H-9)

sc-48365mouse IgG1 κ1-136 (h)WB, IP, IF, IHC(P), ELISAm, r, h
5
(4)

Pol III RPC32 Antibody (C32-1)

sc-21754mouse IgG1 κ(h)WB, IP, IFm, r, h
9
(4)

Pol III RPC39 Antibody (C39-2)

sc-23913mouse IgG1 κ(h)WB, IPm, r, h
2
(5)

Pol III RPC39 Antibody (RPC39)

sc-21753mouse IgG1 κFL (h)WB, IP, IF, IHC(P)m, r, h
2
(4)

RPA16 Antibody (2774C3a)

sc-81636mouse IgG1N-Terminal (h)WB, IPh

new

(2)

RPA40 Antibody (H-6)

sc-374443mouse IgG1 κ1-105 (h)WB, IP, IF, IHC(P), ELISAm, r, h
6
(4)

RPA40 Antibody (H-7)

sc-374444mouse IgG1 κ1-105 (h)WB, IP, IF, ELISAm, r, h

new

(3)

RPA135 Antibody (4H6)

sc-293272mouse IgG2a κ963-1072 (h)WB, IP, IF, IHC(P), ELISAm, r, h
4
(1)

RPA194 Antibody (C-1)

sc-48385mouse IgG2a κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h
96
(11)

RPA194 Antibody (F-6)

sc-46699mouse IgG2b κ1-300 (h)WB, IP, IF, ELISAm, r, h
9
(3)

Phospho-Specific RNA Polymerase Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-Pol II Antibody (8A7)

sc-13583mouse IgM κSer 1801 (h)WB, IP, IF, IHC(P)m, r, h
26
(7)

Non-Mammalian RNA Polymerase Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Pol I/II/III RPB8 Antibody (4WG2)

sc-57982mouse IgG2aN/AWBy

new

(1)

Pol II RPB5 Antibody (3Y11)

sc-101605mouse IgG1N/AWByeast
1
(2)

RNA pol σ F Antibody (1RF18)

sc-101601mouse IgG1N/AWBE. coli

new

(1)

RNA pol σ fecI Antibody (1FE16)

sc-101610mouse IgG1N/AWB, IPE. coli

new

(1)

RNA pol σ H Antibody (3RH3)

sc-101599mouse IgG11-25 (E. coli)WB, IPE. coli

new

(2)

RNA pol σ N Antibody (6RN3)

sc-101598mouse IgG2a88-137 (E. coli)WBE. coli

new

(1)

RNA Polymerase CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Pol II CRISPR/Cas9 KO Plasmid (h2)

sc-400053-KO-2hGene KnockoutGFP0
(0)

Pol II CRISPR/Cas9 KO Plasmid (m)

sc-422732mGene KnockoutGFP0
(0)

Pol II HDR Plasmid (m)

sc-422732-HDRmHomology Directed RepairPuromycin0
(0)

Pol I/II/III RPB8 CRISPR/Cas9 KO Plasmid (h)

sc-406520hGene KnockoutGFP0
(0)

RPA40 CRISPR/Cas9 KO Plasmid (h)

sc-404594hGene KnockoutGFP0
(0)

RPA135 CRISPR/Cas9 KO Plasmid (h)

sc-402818hGene KnockoutGFP0
(0)

RPA194 CRISPR/Cas9 KO Plasmid (h)

sc-400816hGene KnockoutGFP0
(0)

RPA194 HDR Plasmid (h)

sc-400816-HDRhHomology Directed RepairPuromycin0
(0)

RPA194 Double Nickase Plasmid (h)

sc-400816-NIChGene KnockoutPuromycin0
(0)

RPA194 Double Nickase Plasmid (h2)

sc-400816-NIC-2hGene KnockoutPuromycin0
(0)

RNA Polymerase CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Pol II CRISPR Activation Plasmid (h)

sc-400053-ACThGene ActivationPuro, Blast, Hygro0
(0)

Pol II CRISPR Activation Plasmid (h2)

sc-400053-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Pol III RPC32 CRISPR Activation Plasmid (h)

sc-417072-ACThGene ActivationPuro, Blast, Hygro
1
(0)

Pol III RPC32 CRISPR Activation Plasmid (h2)

sc-417072-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

Pol III RPC32 Lentiviral Activation Particles (h)

sc-417072-LAChGene ActivationPuro, Blast, Hygro
1
(0)

Pol III RPC32 Lentiviral Activation Particles (h2)

sc-417072-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

RPA194 CRISPR Activation Plasmid (h)

sc-400816-ACThGene ActivationPuro, Blast, Hygro0
(0)

RNA Polymerase siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Pol II siRNA (h)

sc-36290hGene SilencingN/A0
(0)

Pol II shRNA Plasmid (h)

sc-36290-SHhGene SilencingPuromycin0
(0)

Pol II shRNA (h) Lentiviral Particles

sc-36290-VhGene SilencingPuromycin0
(0)

Pol II siRNA (m)

sc-36291mGene SilencingN/A0
(0)

Pol II shRNA Plasmid (m)

sc-36291-SHmGene SilencingPuromycin0
(0)

Pol II shRNA (m) Lentiviral Particles

sc-36291-VmGene SilencingPuromycin0
(0)

Pol I/II/III RPB6 siRNA (h)

sc-45868hGene SilencingN/A0
(0)

Pol I/II/III RPB6 shRNA Plasmid (h)

sc-45868-SHhGene SilencingPuromycin0
(0)

Pol I/II/III RPB6 shRNA (h) Lentiviral Particles

sc-45868-VhGene SilencingPuromycin0
(0)

Pol I/II/III RPB6 siRNA (m)

sc-45869mGene SilencingN/A0
(0)

Pol I/II/III RPB6 shRNA Plasmid (m)

sc-45869-SHmGene SilencingPuromycin0
(0)

Pol I/II/III RPB6 shRNA (m) Lentiviral Particles

sc-45869-VmGene SilencingPuromycin0
(0)

Pol I/II/III RPB8 siRNA (h)

sc-45866hGene SilencingN/A0
(0)

Pol I/II/III RPB8 shRNA Plasmid (h)

sc-45866-SHhGene SilencingPuromycin0
(0)

Pol I/II/III RPB8 shRNA (h) Lentiviral Particles

sc-45866-VhGene SilencingPuromycin0
(0)

Pol I/II/III RPB8 siRNA (m)

sc-45867mGene SilencingN/A0
(0)

Pol I/II/III RPB8 shRNA Plasmid (m)

sc-45867-SHmGene SilencingPuromycin0
(0)

Pol I/II/III RPB8 shRNA (m) Lentiviral Particles

sc-45867-VmGene SilencingPuromycin0
(0)

RPA16 siRNA (h)

sc-38240hGene SilencingN/A0
(0)

RPA16 shRNA Plasmid (h)

sc-38240-SHhGene SilencingPuromycin0
(0)

RPA16 shRNA (h) Lentiviral Particles

sc-38240-VhGene SilencingPuromycin0
(0)

RPA16 siRNA (m)

sc-38241mGene SilencingN/A0
(0)

RPA16 shRNA Plasmid (m)

sc-38241-SHmGene SilencingPuromycin0
(0)

RPA16 shRNA (m) Lentiviral Particles

sc-38241-VmGene SilencingPuromycin0
(0)

Pol III RPC32 siRNA (h)

sc-43507hGene SilencingN/A
1
(0)

Pol III RPC32 shRNA Plasmid (h)

sc-43507-SHhGene SilencingPuromycin
1
(0)

Pol III RPC32 shRNA (h) Lentiviral Particles

sc-43507-VhGene SilencingPuromycin
1
(0)

Pol III RPC32 siRNA (m)

sc-45840mGene SilencingN/A0
(0)

Pol III RPC32 shRNA Plasmid (m)

sc-45840-SHmGene SilencingPuromycin0
(0)

Pol III RPC32 shRNA (m) Lentiviral Particles

sc-45840-VmGene SilencingPuromycin0
(0)

Pol III RPC39 siRNA (h)

sc-36292hGene SilencingN/A
1
(0)

Pol III RPC39 shRNA Plasmid (h)

sc-36292-SHhGene SilencingPuromycin
1
(0)

Pol III RPC39 shRNA (h) Lentiviral Particles

sc-36292-VhGene SilencingPuromycin
1
(0)

Pol III RPC39 siRNA (m)

sc-45839mGene SilencingN/A0
(0)

Pol III RPC39 shRNA Plasmid (m)

sc-45839-SHmGene SilencingPuromycin0
(0)

Pol III RPC39 shRNA (m) Lentiviral Particles

sc-45839-VmGene SilencingPuromycin0
(0)

RPA40 siRNA (h)

sc-38242hGene SilencingN/A0
(0)

RPA40 shRNA Plasmid (h)

sc-38242-SHhGene SilencingPuromycin0
(0)

RPA40 shRNA (h) Lentiviral Particles

sc-38242-VhGene SilencingPuromycin0
(0)

RPA40 siRNA (m)

sc-38243mGene SilencingN/A0
(0)

RPA40 shRNA Plasmid (m)

sc-38243-SHmGene SilencingPuromycin0
(0)

RPA40 shRNA (m) Lentiviral Particles

sc-38243-VmGene SilencingPuromycin0
(0)

Pol III RPC62 siRNA (h)

sc-76188hGene SilencingN/A
1
(0)

Pol III RPC62 shRNA Plasmid (h)

sc-76188-SHhGene SilencingPuromycin
1
(0)

Pol III RPC62 shRNA (h) Lentiviral Particles

sc-76188-VhGene SilencingPuromycin
1
(0)

RPA135 siRNA (h)

sc-36436hGene SilencingN/A0
(0)

RPA135 shRNA Plasmid (h)

sc-36436-SHhGene SilencingPuromycin0
(0)

RPA135 shRNA (h) Lentiviral Particles

sc-36436-VhGene SilencingPuromycin0
(0)

RPA135 siRNA (m)

sc-36437mGene SilencingN/A0
(0)

RPA135 shRNA Plasmid (m)

sc-36437-SHmGene SilencingPuromycin0
(0)

RPA135 shRNA (m) Lentiviral Particles

sc-36437-VmGene SilencingPuromycin0
(0)

RPA194 siRNA (h)

sc-38244hGene SilencingN/A0
(0)

RPA194 shRNA Plasmid (h)

sc-38244-SHhGene SilencingPuromycin0
(0)

RPA194 shRNA (h) Lentiviral Particles

sc-38244-VhGene SilencingPuromycin0
(0)

RPA194 siRNA (m)

sc-38245mGene SilencingN/A0
(0)

RPA194 shRNA Plasmid (m)

sc-38245-SHmGene SilencingPuromycin0
(0)

RPA194 shRNA (m) Lentiviral Particles

sc-38245-VmGene SilencingPuromycin0
(0)