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RPA40 Antibody (H-7) is a mouse monoclonal IgG1 antibody that detects RPA40 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RPA40 is a critical subunit of RNA polymerase I (Pol I), which plays a vital role in ribosomal RNA synthesis and, consequently, ribosomal biogenesis. Located in the nucleolus, RPA40 is essential for the assembly and stability of the Pol I complex, interacting with other subunits like RPA16 and RPA135 during the early stages of RNA polymerase assembly. The proper functioning of RPA40 is crucial, as RPA40 not only supports Pol I activity but is also a key component of RNA polymerase III, which transcribes other essential RNA molecules. The intricate regulation of RPA40 and its interactions with various signaling pathways highlight RPA40′s importance in cellular growth and proliferation, making anti-RPA40 antibody (H-7) a significant tool for studies related to ribosome biogenesis and its implications in diseases such as cancer.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RPA40 Antibody (H-7) | sc-374444 | 200 µg/ml | $322.00 | |||
RPA40 Antibody (H-7): m-IgG Fc BP-HRP Bundle | sc-540455 | 200 µg Ab; 10 µg BP | $361.00 | |||
RPA40 Antibody (H-7): m-IgG1 BP-HRP Bundle | sc-542134 | 200 µg Ab; 20 µg BP | $361.00 |