Date published: 2026-1-9

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Pol II Antibodies

Santa Cruz Biotechnology provides a broad selection of Pol II Antibodies for advanced research in molecular biology. Pol II Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Pol II, or RNA polymerase II, plays a crucial role in the transcription of protein-coding genes, making it essential for gene expression regulation. Its activity is tightly controlled and is vital for cellular processes such as differentiation, proliferation, and response to environmental signals. Understanding the function and regulation of Pol II is fundamental for insights into various biological processes and disease mechanisms. Researchers worldwide rely on Pol II monoclonal antibodies to investigate transcriptional mechanisms in both normal and pathological conditions. Advanced research techniques utilizing Pol II monoclonal antibodies have revealed significant insights into gene regulation pathways. The high-quality monoclonal antibodies from Santa Cruz Biotechnology enable researchers to make meaningful contributions to the scientific community's understanding of transcriptional regulation and its impact on human health.

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Pol II Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Pol II Antibody (CTD4H8)

sc-47701mouse IgG1 κSer-5 (h)WB, IP, IF, IHC(P)m, r, h
112
(28)

Pol II Antibody (F-12)

sc-55492mouse IgG2b κ1-224 (h)WB, IP, IF, IHC(P), ELISAm, r, h
59
(9)

Pol II Antibody (8WG16)

sc-56767mouse IgG2a κ(wheat germ)WB, IP, IFm, r, h, Xenopus, C. elegans, yeast, wheat germ and bovine
103
(14)

Pol II Antibody (A-10)

sc-17798mouse IgG2b κ1-224 (h)WB, IP, IF, ELISAm, r, h
48
(12)

Pol II Antibody (3WG2)

sc-21750mouse IgM κconserved heptapeptideWB, IPm, r, h
5
(2)

Pol II Antibody (mara-3)

sc-65884mouse IgM κC-Terminal (yeast)WB, IPm, r, h
1
(1)

Pol II Antibody (1.BB.61)

sc-71917mouse IgG2a κ(wheat germ)WB, IP, IFm, r, h, Xenopus, C. elegans, yeast, wheat germ and bovine
2
(1)

Pol II CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Pol II CRISPR/Cas9 KO Plasmid (h2)

sc-400053-KO-2hGene KnockoutGFP0
(0)

Pol II Double Nickase Plasmid (h)

sc-400053-NIChGene KnockoutPuromycin0
(0)

Pol II Double Nickase Plasmid (h2)

sc-400053-NIC-2hGene KnockoutPuromycin0
(0)

Pol II CRISPR/Cas9 KO Plasmid (m)

sc-422732mGene KnockoutGFP0
(0)

Pol II HDR Plasmid (m)

sc-422732-HDRmHomology Directed RepairPuromycin0
(0)

Pol II Double Nickase Plasmid (m)

sc-422732-NICmGene KnockoutPuromycin0
(0)

Pol II Double Nickase Plasmid (m2)

sc-422732-NIC-2mGene KnockoutPuromycin0
(0)

Pol II CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Pol II CRISPR Activation Plasmid (h)

sc-400053-ACThGene ActivationPuro, Blast, Hygro0
(0)

Pol II CRISPR Activation Plasmid (h2)

sc-400053-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Pol II Lentiviral Activation Particles (h)

sc-400053-LAChGene ActivationPuro, Blast, Hygro0
(0)

Pol II Lentiviral Activation Particles (h2)

sc-400053-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Pol II CRISPR Activation Plasmid (m)

sc-422732-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Pol II CRISPR Activation Plasmid (m2)

sc-422732-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Pol II Lentiviral Activation Particles (m)

sc-422732-LACmGene ActivationPuro, Blast, Hygro0
(0)

Pol II Lentiviral Activation Particles (m2)

sc-422732-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Pol II siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Pol II siRNA (h)

sc-36290hGene SilencingN/A0
(0)

Pol II shRNA Plasmid (h)

sc-36290-SHhGene SilencingPuromycin0
(0)

Pol II shRNA (h) Lentiviral Particles

sc-36290-VhGene SilencingPuromycin0
(0)

Pol II siRNA (m)

sc-36291mGene SilencingN/A0
(0)

Pol II shRNA Plasmid (m)

sc-36291-SHmGene SilencingPuromycin0
(0)

Pol II shRNA (m) Lentiviral Particles

sc-36291-VmGene SilencingPuromycin0
(0)