Pol I/II/III RPB8 Antibody (B-2): sc-398512

Pol I/II/III RPB8 Antibody (B-2) is a mouse monoclonal IgG1 kappa light chain antibody that detects Pol I/II/III RPB8 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Pol I/II/III RPB8 antibody (B-2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Pol I/II/III RPB8 plays a crucial role in transcription as a shared subunit among three distinct classes of RNA polymerases in eukaryotic cells—RNA polymerase I, II, and III. These polymerases are responsible for synthesizing different types of RNA, with Pol I transcribing ribosomal RNA, Pol II synthesizing messenger RNA and small nuclear RNA, and Pol III producing transfer RNA and 5S ribosomal RNA. RPB8 subunit is vital for polymerase assembly and function, contributing to structural integrity and stability of transcription machinery. Understanding RPB8 interactions and functions is essential for elucidating gene expression regulation complexities and implications in various biological processes and diseases.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Pol I/II/III RPB8 Antibody (B-2) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-Pol I/II/III RPB8 Antibody (B-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Pol I/II/III RPB8 Antibody (B-2) Specifications

Alternate Product Name: Pol I/II/III RPB8

Product Clone Name: B-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-150

Epitope Target: Pol I/II/III RPB8

Epitope Species: human

Product Reactivity/Detection: Pol I/II/III RPB8

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Pol I/II/III RPB8 Antibody (B-2): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin