RNA pol σ fecI Antibody (1FE16): sc-101610

RNA pol σ fecI Antibody (1FE16) is a mouse monoclonal IgG1 antibody that detects RNA polymerase σ factor fecI of E. coli origin by western blotting (WB) and immunoprecipitation (IP). Anti-RNA pol σ fecI antibody (1FE16) is available as the non-conjugated form. RNA polymerase σ factor fecI is a 173 amino acid protein that plays a crucial role in the transcription of fec transport genes, which are essential for the cellular regulation of ferric citrate. RNA polymerase σ factor fecI belongs to the extracytoplasmic function subfamily of the E. coli sigma-70 factor family, which is vital for bacterial adaptation to environmental changes. Sigma factors, including RNA pol σ fecI, function as initiation factors that facilitate the binding of RNA polymerase to specific promoter regions, thereby initiating transcription. RNA pol σ fecI′s ability to direct the transcription of genes involved in iron transport is particularly important, as iron is a critical nutrient for bacterial growth and metabolism. Understanding RNA pol σ fecI′s function and role in gene regulation provides insights into bacterial physiology and iron acquisition mechanisms, which may have implications for developing antimicrobial strategies.

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RNA pol σ fecI Antibody (1FE16) References:

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