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Pol I/II/III RPB8 Antibody (SP-75) is a mouse monoclonal IgG1 antibody that detects RPB8 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-RPB8 antibody (SP-75) plays a crucial role in the study of RNA polymerases, as RPB8 is a vital subunit shared among all three classes of RNA polymerases—Pol I, Pol II, and Pol III—responsible for synthesizing different types of RNA. RPB8 is located in the nucleus, where RPB8 contributes to the assembly and stability of RNA polymerase complexes, which are essential for transcription of ribosomal RNA, messenger RNA, and transfer RNA. Understanding RPB8 localization is important because this highlights RPB8′s role in regulating gene expression and maintaining cellular function. Proper functioning of RNA polymerases is critical for cellular processes, including growth, differentiation, and response to environmental signals, making RPB8 a significant target for research in molecular biology and genetics. With RPB8′s ability to interact with various other subunits and proteins involved in transcription, RPB8 monoclonal antibody (SP-75) is an invaluable tool for researchers aiming to explore the complexities of gene regulation and RNA synthesis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pol I/II/III RPB8 Antibody (SP-75) | sc-134422 | 100 µg/ml | $339.00 |