Date published: 2025-10-18

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ERK Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of ERK Antibodies for advanced research in cell signaling pathways. ERK Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Extracellular signal-regulated kinases (ERKs) play a crucial role in mediating cellular responses to growth factors and stress signals, influencing processes such as proliferation, differentiation, and survival. ERK dysregulation is often implicated in various diseases, including cancer, making ERK research essential for understanding cellular pathways. By studying ERK signaling, researchers can gain insights into therapeutic targets and potential interventions. ERK monoclonal antibodies enable detailed investigation of signal transduction mechanisms and their impact on cellular function. Researchers can explore molecular interactions and regulatory mechanisms governing ERK activity in normal and pathological conditions. ERK monoclonal antibodies support cutting-edge research that advances understanding of disease mechanisms and potential therapeutic strategies. Santa Cruz Biotechnology monoclonal antibodies for ERK research empower scientists to make meaningful contributions to biomedical discoveries and therapeutic development.

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ERK Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

ERK 1 Antibody (G-8)

sc-271269mouse IgG2b κ291-335 (r)WB, IP, IF, IHC(P), ELISAm, r, h
58
(27)

ERK 1 Antibody (E-6)

sc-271270mouse IgG1 κ291-335 (r)WB, IP, IF, IHC(P), ELISAm, r, h
32
(9)

ERK 1 Antibody (G-12)

sc-376852mouse IgG1 κ341-367 (r)WB, IP, IF, ELISAm, r, h, chicken and frog
8
(2)

ERK 1 Antibody (E-12)

sc-271291mouse IgG3 κ291-335 (r)WB, IP, IF, IHC(P), ELISAm, r, h
8
(2)

ERK 1/2 Antibody (C-9)

sc-514302mouse IgG2a κ101-172 (h)WB, IP, IF, IHC(P), ELISAm, r, h
534
(74)

ERK 1/2 Antibody (MK1)

sc-135900mouse IgG1 κ325-345 (r)WB, IP, IFm, r, h and canine
322
(18)

ERK 2 Antibody (D-2)

sc-1647mouse IgG2b κ345-358 (h)WB, IP, IF, IHC(P), FCM, ELISAm, r, h
612
(31)

ERK 2 Antibody (12A4)

sc-81457mouse IgG1200-250 (h)WB, IPm, r, h
26
(5)

ERK 2 Antibody (H-9)

sc-271451mouse IgG2a κ276-333 (r)WB, IP, IF, IHC(P), ELISAm, r, h
5
(2)

ERK 2 Antibody (6G11)

sc-81458mouse IgG1C-Terminal (h)WB, IPm, r, h and canine
5
(3)

ERK 2 Antibody (6H3)

sc-81459mouse IgG1N-Terminal (h)WB, IPm, r, h and canine
10
(3)

ERK 2 Antibody (C-8)

sc-271458mouse IgG2b κ276-333 (r)WB, IP, IF, IHC(P), ELISAm, r, h
3
(3)

ERK 2 Antibody (4C11C11C4)

sc-65981mouse IgG2a κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(5)

ERK 2 Antibody (33)

sc-136288mouse IgG2b219-358 (r)WB, IP, IF, IHC(P)m, r, h and canine
7
(2)

ERK 3 Antibody (B-10)

sc-365234mouse IgG1 κ345-377 (r)WB, IP, IF, IHC(P), ELISAm, r, h
3
(5)

ERK 3 Antibody (E-3)

sc-374239mouse IgG1 κ565-721 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(3)

ERK 3 Antibody (G-2)

sc-393371mouse IgG2b κ304-339 (r)WB, IP, IF, ELISAm, r, h

new

(1)

ERK 5 Antibody (C-7)

sc-398015mouse IgG1 κ671-698 (h)WB, IP, IF, IHC(P), ELISAm, r, h
16
(9)

ERK 5 Antibody (C-11)

sc-393405mouse IgG1 κ786-815 (h)WB, IP, IF, ELISAm, r, h
2
(3)

ERK 5 Antibody (12F2)

sc-81460mouse IgG1N-Terminal (h)WB, IPm, r, h and canine
3
(3)

Phospho-Specific ERK Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-ERK Antibody (E-4)

sc-7383mouse IgG2a κTyr 204 (h)WB, IP, IF, IHC(P), ELISAm, r, h
3,280
(101)

p-ERK 1/2 Antibody (12D4)

sc-81492mouse IgG1Thr 202/Tyr 204 (h)WB, IP, IFm, r, h and canine
250
(11)

p-ERK 1/2 Antibody (pT202/pY204.22A)

sc-136521mouse IgG1 κThr 203/Tyr 205 (r)WB, IF, IHC(P)m, r, h
127
(31)

p-ERK 5 Antibody (1.T218/Y220)

sc-135760mouse IgG1 κThr 218/Tyr 220 (h)WB, IP, ELISAm, r, h
12
(1)

ERK CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ERK 1 CRISPR/Cas9 KO Plasmid (h2)

sc-400010-KO-2hGene KnockoutGFP0
(0)

ERK 1 HDR Plasmid (h2)

sc-400010-HDR-2hHomology Directed RepairPuromycin0
(0)

ERK 1 Double Nickase Plasmid (h)

sc-400010-NIChGene KnockoutPuromycin0
(0)

ERK 1 Double Nickase Plasmid (h2)

sc-400010-NIC-2hGene KnockoutPuromycin0
(0)

ERK 1 CRISPR/Cas9 KO Plasmid (m)

sc-424052mGene KnockoutGFP0
(0)

ERK 1 HDR Plasmid (m)

sc-424052-HDRmHomology Directed RepairPuromycin0
(0)

ERK 1 Double Nickase Plasmid (m)

sc-424052-NICmGene KnockoutPuromycin0
(0)

ERK 1 Double Nickase Plasmid (m2)

sc-424052-NIC-2mGene KnockoutPuromycin0
(0)

ERK 2 CRISPR/Cas9 KO Plasmid (h)

sc-400043hGene KnockoutGFP0
(0)

ERK 2 HDR Plasmid (h)

sc-400043-HDRhHomology Directed RepairPuromycin0
(0)

ERK 2 Double Nickase Plasmid (h)

sc-400043-NIChGene KnockoutPuromycin0
(0)

ERK 2 Double Nickase Plasmid (h2)

sc-400043-NIC-2hGene KnockoutPuromycin0
(0)

ERK 2 CRISPR/Cas9 KO Plasmid (m)

sc-424048mGene KnockoutGFP0
(0)

ERK 2 HDR Plasmid (m)

sc-424048-HDRmHomology Directed RepairPuromycin0
(0)

ERK 2 Double Nickase Plasmid (m)

sc-424048-NICmGene KnockoutPuromycin0
(0)

ERK 2 Double Nickase Plasmid (m2)

sc-424048-NIC-2mGene KnockoutPuromycin0
(0)

ERK 3 CRISPR/Cas9 KO Plasmid (h)

sc-403457hGene KnockoutGFP0
(0)

ERK 3 HDR Plasmid (h)

sc-403457-HDRhHomology Directed RepairPuromycin0
(0)

ERK 3 Double Nickase Plasmid (h)

sc-403457-NIChGene KnockoutPuromycin0
(0)

ERK 3 Double Nickase Plasmid (h2)

sc-403457-NIC-2hGene KnockoutPuromycin0
(0)

ERK 3 CRISPR/Cas9 KO Plasmid (m)

sc-424486mGene KnockoutGFP0
(0)

ERK 3 HDR Plasmid (m)

sc-424486-HDRmHomology Directed RepairPuromycin0
(0)

ERK 3 Double Nickase Plasmid (m)

sc-424486-NICmGene KnockoutPuromycin0
(0)

ERK 3 Double Nickase Plasmid (m2)

sc-424486-NIC-2mGene KnockoutPuromycin0
(0)

ERK 4 CRISPR/Cas9 KO Plasmid (h)

sc-406660hGene KnockoutGFP0
(0)

ERK 4 HDR Plasmid (h)

sc-406660-HDRhHomology Directed RepairPuromycin0
(0)

ERK 4 Double Nickase Plasmid (h)

sc-406660-NIChGene KnockoutPuromycin0
(0)

ERK 4 Double Nickase Plasmid (h2)

sc-406660-NIC-2hGene KnockoutPuromycin0
(0)

ERK 4 CRISPR/Cas9 KO Plasmid (m)

sc-432558mGene KnockoutGFP0
(0)

ERK 4 HDR Plasmid (m)

sc-432558-HDRmHomology Directed RepairPuromycin0
(0)

ERK 4 Double Nickase Plasmid (m)

sc-432558-NICmGene KnockoutPuromycin0
(0)

ERK 4 Double Nickase Plasmid (m2)

sc-432558-NIC-2mGene KnockoutPuromycin0
(0)

ERK 5 CRISPR/Cas9 KO Plasmid (h)

sc-400891hGene KnockoutGFP
1
(0)

ERK 5 HDR Plasmid (h)

sc-400891-HDRhHomology Directed RepairPuromycin
1
(0)

ERK 5 Double Nickase Plasmid (h)

sc-400891-NIChGene KnockoutPuromycin
1
(0)

ERK 5 Double Nickase Plasmid (h2)

sc-400891-NIC-2hGene KnockoutPuromycin
1
(0)

ERK 5 CRISPR/Cas9 KO Plasmid (m)

sc-423907mGene KnockoutGFP0
(0)

ERK 5 HDR Plasmid (m)

sc-423907-HDRmHomology Directed RepairPuromycin0
(0)

ERK 5 Double Nickase Plasmid (m)

sc-423907-NICmGene KnockoutPuromycin0
(0)

ERK 5 Double Nickase Plasmid (m2)

sc-423907-NIC-2mGene KnockoutPuromycin0
(0)

ERK CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ERK 1 CRISPR Activation Plasmid (h)

sc-400010-ACThGene ActivationPuro, Blast, Hygro0
(0)

ERK 1 CRISPR Activation Plasmid (h2)

sc-400010-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ERK 1 Lentiviral Activation Particles (h)

sc-400010-LAChGene ActivationPuro, Blast, Hygro0
(0)

ERK 1 Lentiviral Activation Particles (h2)

sc-400010-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ERK 1 CRISPR Activation Plasmid (m)

sc-424052-ACTmGene ActivationPuro, Blast, Hygro0
(0)

ERK 1 CRISPR Activation Plasmid (m2)

sc-424052-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

ERK 1 Lentiviral Activation Particles (m)

sc-424052-LACmGene ActivationPuro, Blast, Hygro0
(0)

ERK 1 Lentiviral Activation Particles (m2)

sc-424052-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

ERK 2 CRISPR Activation Plasmid (h)

sc-400043-ACThGene ActivationPuro, Blast, Hygro0
(0)

ERK 2 CRISPR Activation Plasmid (h2)

sc-400043-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ERK 2 Lentiviral Activation Particles (h)

sc-400043-LAChGene ActivationPuro, Blast, Hygro0
(0)

ERK 2 Lentiviral Activation Particles (h2)

sc-400043-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ERK 2 CRISPR Activation Plasmid (m)

sc-424048-ACTmGene ActivationPuro, Blast, Hygro0
(0)

ERK 2 CRISPR Activation Plasmid (m2)

sc-424048-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

ERK 2 Lentiviral Activation Particles (m)

sc-424048-LACmGene ActivationPuro, Blast, Hygro0
(0)

ERK 2 Lentiviral Activation Particles (m2)

sc-424048-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

ERK 3 CRISPR Activation Plasmid (h)

sc-403457-ACThGene ActivationPuro, Blast, Hygro0
(0)

ERK 3 CRISPR Activation Plasmid (h2)

sc-403457-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ERK 3 Lentiviral Activation Particles (h)

sc-403457-LAChGene ActivationPuro, Blast, Hygro0
(0)

ERK 3 Lentiviral Activation Particles (h2)

sc-403457-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ERK 3 CRISPR Activation Plasmid (m)

sc-424486-ACTmGene ActivationPuro, Blast, Hygro0
(0)

ERK 3 CRISPR Activation Plasmid (m2)

sc-424486-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

ERK 3 Lentiviral Activation Particles (m)

sc-424486-LACmGene ActivationPuro, Blast, Hygro0
(0)

ERK 3 Lentiviral Activation Particles (m2)

sc-424486-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

ERK 4 CRISPR Activation Plasmid (h)

sc-406660-ACThGene ActivationPuro, Blast, Hygro0
(0)

ERK 4 CRISPR Activation Plasmid (h2)

sc-406660-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ERK 4 Lentiviral Activation Particles (h)

sc-406660-LAChGene ActivationPuro, Blast, Hygro0
(0)

ERK 4 Lentiviral Activation Particles (h2)

sc-406660-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ERK 4 CRISPR Activation Plasmid (m)

sc-432558-ACTmGene ActivationPuro, Blast, Hygro0
(0)

ERK 4 CRISPR Activation Plasmid (m2)

sc-432558-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

ERK 4 Lentiviral Activation Particles (m)

sc-432558-LACmGene ActivationPuro, Blast, Hygro0
(0)

ERK 4 Lentiviral Activation Particles (m2)

sc-432558-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

ERK 5 CRISPR Activation Plasmid (h)

sc-400891-ACThGene ActivationPuro, Blast, Hygro
1
(0)

ERK 5 CRISPR Activation Plasmid (h2)

sc-400891-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

ERK 5 Lentiviral Activation Particles (h)

sc-400891-LAChGene ActivationPuro, Blast, Hygro
1
(0)

ERK 5 Lentiviral Activation Particles (h2)

sc-400891-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

ERK 5 CRISPR Activation Plasmid (m)

sc-423907-ACTmGene ActivationPuro, Blast, Hygro0
(0)

ERK 5 CRISPR Activation Plasmid (m2)

sc-423907-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

ERK 5 Lentiviral Activation Particles (m)

sc-423907-LACmGene ActivationPuro, Blast, Hygro0
(0)

ERK 5 Lentiviral Activation Particles (m2)

sc-423907-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

ERK siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ERK 1 siRNA (h)

sc-29307hGene SilencingN/A
52
(0)

ERK 1 siRNA (h2)

sc-44205hGene SilencingN/A
3
(0)

ERK 1 shRNA Plasmid (h)

sc-29307-SHhGene SilencingPuromycin
52
(0)

ERK 1 shRNA Plasmid (h2)

sc-44205-SHhGene SilencingPuromycin
3
(0)

ERK 1 shRNA (h) Lentiviral Particles

sc-29307-VhGene SilencingPuromycin
52
(0)

ERK 1 shRNA (h2) Lentiviral Particles

sc-44205-VhGene SilencingPuromycin
3
(0)

ERK 1 siRNA (m)

sc-29308mGene SilencingN/A
33
(0)

ERK 1 siRNA (m2)

sc-44206mGene SilencingN/A
1
(0)

ERK 1 shRNA Plasmid (m)

sc-29308-SHmGene SilencingPuromycin
33
(0)

ERK 1 shRNA Plasmid (m2)

sc-44206-SHmGene SilencingPuromycin
1
(0)

ERK 1 shRNA (m) Lentiviral Particles

sc-29308-VmGene SilencingPuromycin
33
(0)

ERK 1 shRNA (m2) Lentiviral Particles

sc-44206-VmGene SilencingPuromycin
1
(0)

ERK 1 siRNA (r)

sc-156030rGene SilencingN/A
6
(0)

ERK 1 siRNA (bovine)

sc-270002bovineGene SilencingN/A0
(0)

ERK 2 siRNA (h)

sc-35335hGene SilencingN/A
59
(1)

ERK 2 siRNA (h2)

sc-44223hGene SilencingN/A
3
(0)

ERK 2 shRNA Plasmid (h)

sc-35335-SHhGene SilencingPuromycin
59
(1)

ERK 2 shRNA Plasmid (h2)

sc-44223-SHhGene SilencingPuromycin
3
(0)

ERK 2 shRNA (h) Lentiviral Particles

sc-35335-VhGene SilencingPuromycin
59
(1)

ERK 2 shRNA (h2) Lentiviral Particles

sc-44223-VhGene SilencingPuromycin
3
(0)

ERK 2 siRNA (m)

sc-35336mGene SilencingN/A
20
(0)

ERK 2 siRNA (m2)

sc-44224mGene SilencingN/A
1
(0)

ERK 2 shRNA Plasmid (m)

sc-35336-SHmGene SilencingPuromycin
20
(0)

ERK 2 shRNA Plasmid (m2)

sc-44224-SHmGene SilencingPuromycin
1
(0)

ERK 2 shRNA (m) Lentiviral Particles

sc-35336-VmGene SilencingPuromycin
20
(0)

ERK 2 shRNA (m2) Lentiviral Particles

sc-44224-VmGene SilencingPuromycin
1
(0)

ERK 2 siRNA (r)

sc-156031rGene SilencingN/A
7
(0)

ERK 3 siRNA (h)

sc-35337hGene SilencingN/A0
(0)

ERK 3 shRNA Plasmid (h)

sc-35337-SHhGene SilencingPuromycin0
(0)

ERK 3 shRNA (h) Lentiviral Particles

sc-35337-VhGene SilencingPuromycin0
(0)

ERK 3 siRNA (m)

sc-35338mGene SilencingN/A
1
(0)

ERK 3 shRNA Plasmid (m)

sc-35338-SHmGene SilencingPuromycin
1
(0)

ERK 3 shRNA (m) Lentiviral Particles

sc-35338-VmGene SilencingPuromycin
1
(0)

ERK 4 siRNA (h)

sc-62280hGene SilencingN/A
1
(0)

ERK 4 shRNA Plasmid (h)

sc-62280-SHhGene SilencingPuromycin
1
(0)

ERK 4 shRNA (h) Lentiviral Particles

sc-62280-VhGene SilencingPuromycin
1
(0)

ERK 4 siRNA (m)

sc-62281mGene SilencingN/A0
(0)

ERK 4 shRNA Plasmid (m)

sc-62281-SHmGene SilencingPuromycin0
(0)

ERK 4 shRNA (m) Lentiviral Particles

sc-62281-VmGene SilencingPuromycin0
(0)

ERK 5 siRNA (h)

sc-35339hGene SilencingN/A
3
(0)

ERK 5 shRNA Plasmid (h)

sc-35339-SHhGene SilencingPuromycin
3
(0)

ERK 5 shRNA (h) Lentiviral Particles

sc-35339-VhGene SilencingPuromycin
3
(0)

ERK 5 siRNA (m)

sc-35340mGene SilencingN/A
8
(0)

ERK 5 shRNA Plasmid (m)

sc-35340-SHmGene SilencingPuromycin
8
(0)

ERK 5 shRNA (m) Lentiviral Particles

sc-35340-VmGene SilencingPuromycin
8
(0)