ERK 2 Antibody (4C11C11C4): sc-65981
- ERK 2 Antibody (4C11C11C4) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 200 µg/ml
- raised against purified full length recombinant ERK 2 of human origin
- recommended for detection of ERK 2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See ERK 2 (D-2): sc-1647 for ERK 2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ERK 2 Antibody (4C11C11C4) for WB and IHC(P) applications. These reagents are now offered in bundles with ERK 2 Antibody (4C11C11C4) (see ordering information below).
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ERK 2 Antibody (4C11C11C4) is a mouse monoclonal IgG2a kappa light chain antibody, raised against purified full-length recombinant ERK 2 of human origin. ERK2, also known as extracellular signal-regulated kinase 2, is a critical component of the mitogen-activated protein kinase (MAPK) signaling pathways that regulate a wide range of cellular processes including development, transcription regulation, differentiation, and proliferation. Activated by upstream kinases such as MAP kinase kinase (MEK), MEK kinase, and Raf-1, ERK2 undergoes phosphorylation at specific tyrosine and threonine residues within the conserved Threonine-Glutamate-Tyrosine (TEY) motif. Upon activation, ERK2 translocates from the cytoplasm to the nucleus, a crucial step that enables phosphorylation of nuclear substrates and influences gene expression. This nuclear localization is essential for ERK2′s role in cell cycle progression and differentiation. Anti-ERK2 antibody (4C11C11C4) is reactive with mouse, rat, and human ERK2 in applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). ERK2 monoclonal antibody (4C11C11C4) is an invaluable tool for researchers investigating the MAPK/ERK signaling pathway, signal transduction mechanisms, and related cellular functions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ERK 2 Antibody (4C11C11C4) | sc-65981 | 200 µg/ml | $316.00 | |||
ERK 2 Antibody (4C11C11C4): m-IgG Fc BP-HRP Bundle | sc-537181 | 200 µg Ab; 10 µg BP | $354.00 | |||
ERK 2 Antibody (4C11C11C4): m-IgGκ BP-HRP Bundle | sc-534383 | 200 µg Ab; 40 µg BP | $354.00 | |||
ERK 2 Antibody (4C11C11C4): m-IgG2a BP-HRP Bundle | sc-547938 | 200 µg Ab; 10 µg BP | $354.00 |