ERK Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $32.00 $210.00 $720.00 $1128.00 $2302.00 $3066.00 $5106.00 | 22 | |
Apigenin is a flavonoid that modulates ERK signaling through its ability to interact with specific protein domains, influencing phosphorylation events. Its unique structure facilitates binding to regulatory sites, altering conformational dynamics and enzymatic activity. This compound exhibits notable reaction kinetics, promoting a nuanced balance in cellular signaling networks. By fine-tuning these pathways, apigenin plays a role in the intricate regulation of cellular responses and fate. | ||||||
Andrographolide | 5508-58-7 | sc-205594 sc-205594A | 50 mg 100 mg | $15.00 $39.00 | 7 | |
Andrographolide is a diterpenoid lactone that engages with the ERK signaling pathway by selectively inhibiting upstream kinases, thereby modulating phosphorylation cascades. Its unique stereochemistry allows for specific interactions with target proteins, influencing their conformational states and activity. The compound exhibits distinct reaction kinetics, promoting a dynamic equilibrium in cellular signaling, which can lead to altered gene expression and cellular behavior. | ||||||
Ibrutinib-d5 | 1553977-17-5 | sc-495736A sc-495736 sc-495736B | 500 µg 1 mg 5 mg | $156.00 $300.00 $1250.00 | 1 | |
Ibrutinib-d5, a deuterated variant of Ibrutinib, exhibits unique isotopic characteristics that influence its reactivity and interaction with biological targets. The incorporation of deuterium enhances its kinetic isotope effects, allowing for precise tracking of reaction mechanisms. This modification can alter binding affinities and conformational dynamics, providing a deeper understanding of molecular pathways. Its distinct isotopic labeling also aids in advanced spectroscopic techniques, revealing intricate details of molecular behavior. | ||||||
ML-9 | 105637-50-1 | sc-200519 sc-200519A sc-200519B sc-200519C | 10 mg 50 mg 100 mg 250 mg | $110.00 $440.00 $660.00 $1200.00 | 2 | |
ML-9 is a selective inhibitor that targets the ERK pathway by disrupting the activity of specific kinases involved in signal transduction. Its unique structural features facilitate precise binding to regulatory sites, influencing downstream signaling events. The compound exhibits notable reaction kinetics, allowing for rapid modulation of phosphorylation states, which can significantly impact cellular responses and metabolic processes. Its interactions contribute to a nuanced regulation of cellular dynamics. | ||||||
ERK Inhibitor III | 331656-92-9 | sc-221595 | 5 mg | $200.00 | 4 | |
ERK Inhibitor III is a potent modulator of the ERK signaling cascade, characterized by its ability to selectively bind to the ATP-binding pocket of ERK kinases. This binding alters the conformational dynamics of the enzyme, effectively hindering its phosphorylation activity. The compound demonstrates unique allosteric effects, influencing substrate affinity and reaction rates, thereby fine-tuning cellular signaling pathways and enhancing the understanding of kinase regulation in various biological contexts. | ||||||