ERK 2 Antibody (H-9): sc-271451
- ERK 2 Antibody (H-9) is a mouse monoclonal IgG2a κ, cited in 5 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 276-333 within subdomain XI of rat ERK 2-encoded MAP kinase p42
- recommended for detection of ERK 2 p42 of mouse, rat, human and avian origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and canine, bovine, porcine and avian
- See ERK 2 (D-2): sc-1647 for ERK 2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ERK 2 Antibody (H-9) for WB and IHC(P) applications. These reagents are now offered in bundles with ERK 2 Antibody (H-9) (see ordering information below).
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ERK 2 Antibody (H-9) is a mouse monoclonal IgG2a antibody that detects ERK 2 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). ERK2 (Extracellular Signal-Regulated Kinase 2), also known as MAPK1 or p42 MAPK, plays a crucial role in the mitogen-activated protein kinase (MAPK) signaling pathways, which are essential for transmitting signals from the cell surface to the nucleus, thereby regulating key cellular processes such as proliferation, differentiation, and survival. ERK2 is primarily located in the cytoplasm but translocates to the nucleus upon activation, where ERK2 phosphorylates target proteins that influence gene expression and cellular responses. ERK2 activation is tightly regulated through phosphorylation by upstream kinases, including MAP kinase kinase (MEK), and is critical for proper functioning of various physiological processes. The human ERK2 gene, located on chromosome 22q11.21, encodes a 360-amino acid protein that is highly conserved across species, underscoring ERK2′s importance in cellular signaling pathways. With detection capabilities across multiple species and applications, anti-ERK2 antibody (H-9) is an invaluable tool for researchers studying MAPK signaling and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ERK 2 Antibody (H-9) | sc-271451 | 200 µg/ml | $316.00 | |||
ERK 2 Antibody (H-9): m-IgG Fc BP-HRP Bundle | sc-537636 | 200 µg Ab; 10 µg BP | $354.00 | |||
ERK 2 Antibody (H-9): m-IgGκ BP-HRP Bundle | sc-534966 | 200 µg Ab; 40 µg BP | $354.00 | |||
ERK 2 Antibody (H-9): m-IgG2a BP-HRP Bundle | sc-548074 | 200 µg Ab; 10 µg BP | $354.00 | |||
ERK 2 (H-9) Neutralizing Peptide | sc-271451 P | 100 µg/0.5 ml | $68.00 |