p-Ac-Histone H3 Antibody (APH3-64): sc-56739

p-Ac-Histone H3 Antibody (APH3-64) is a mouse monoclonal IgG2a kappa light chain antibody that detects p-Ac-Histone H3 in mouse, rat, human, Drosophila, Xenopus, C. elegans, and bovine samples through western blotting (WB) and immunoprecipitation (IP) applications. anti-p-Ac-Histone H3 antibody (APH3-64) is available in a non-conjugated form, specifically designed for researchers studying chromatin structure and function. p-Ac-Histone H3 plays a crucial role in gene expression regulation through histone modifications that promote or inhibit transcription. Phosphorylation of Ser 10 and acetylation of Lys 9 on Histone H3 are significant during the cell cycle, as these modifications associate with chromatin remodeling and immediate-early gene activation, essential for cellular responses to various stimuli. Dynamic interplay of these post-translational modifications influences chromatin accessibility and impacts DNA repair and replication. Understanding p-Ac-Histone H3 modifications is vital for elucidating mechanisms underlying gene regulation and cellular differentiation, making p-Ac-Histone H3 (APH3-64) monoclonal antibody an invaluable tool for epigenetics and molecular biology research.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-p-Ac-Histone H3 Antibody (APH3-64) has 4 citations in a variety of scientific publications.

Primary antibodies like Anti-p-Ac-Histone H3 Antibody (APH3-64) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

p-Ac-Histone H3 Antibody (APH3-64) Specifications

Alternate Product Name: phospho acetyl Histone H3

Product Clone Name: APH3-64

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: Lys 9/Ser 10

Epitope Target: Histone H3

Epitope Species: human

Product Reactivity/Detection: Ser 10 phosphorylated and Lys 9 acetylated Histone H3

Species Reactivity/Detection: mouse, rat, human, Drosophila, Xenopus , C. elegans, bovine

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 4 citations in various scientific publications

Available Conjugates/Forms for p-Ac-Histone H3 Antibody (APH3-64): N/A

The preferred Ac-Histone H3 antibody is Ac-Histone H3 Antibody (AH3-120): sc-56616.