p-Histone H3 Antibody (HTA28): sc-56745
- p-Histone H3 Antibody (HTA28) is a rat monoclonal IgG2a, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids Ser 28 of p-Histone H3 of human origin
- recommended for detection of Ser 28 phosphorylated Histone H3 of mouse, rat, human and bovine origin by WB, IP, IF and FCM; not recommended for detection of the unphosphorylated epitope
- See p-Histone H3 (C-2): sc-374669 for p-Histone H3 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for p-Histone H3 Antibody (HTA28). This work is in progress.
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p-Histone H3 Antibody (HTA28) is a rat monoclonal IgG2a antibody that detects p-Histone H3 (p-H3) in mouse, rat, human, and bovine samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). p-Histone H3 (HTA28) antibody specifically recognizes phosphorylated forms of Histone H3, which play a crucial role in regulating gene expression during the cell cycle. Phosphorylation of Histone H3, particularly at serine residues 10 and 28, is essential for chromatin remodeling and serves as a key marker of mitotic progression. This post-translational modification facilitates dynamic changes in chromatin structure necessary for proper chromosome segregation during cell division. By enabling specific regulatory protein binding, phosphorylated Histone H3 helps ensure appropriate timing and levels of gene expression, which is vital for maintaining cellular function and preventing diseases such as cancer. Anti-p-Histone H3 antibody (HTA28) detection of these modifications makes p-H3 (HTA28) monoclonal antibody an invaluable tool for researchers studying cell cycle dynamics and chromatin biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-Histone H3 Antibody (HTA28) | sc-56745 | 200 µg/ml | $316.00 |