Date published: 2026-7-19

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Dnmt Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Dnmt Antibodies for research in epigenetics and gene regulation. Dnmt Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). DNA methyltransferases (Dnmt) play a crucial role in the regulation of gene expression through the addition of methyl groups to DNA, influencing cellular processes such as development, differentiation, and genomic stability. Aberrant Dnmt activity is associated with various diseases, including cancer, making DNA methyltransferase research essential for understanding biological mechanisms in health and disease. Dnmt monoclonal antibodies enable precise detection and analysis of DNA methylation patterns across different cell types and tissues. Researchers can investigate specific methylation sites and track changes in DNA methylation during cellular development and disease progression. Advanced visualization techniques using fluorescent conjugates like horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC) allow for detailed examination of methylation dynamics. Santa Cruz Biotechnology monoclonal antibodies for Dnmt research contribute to advancing our understanding of epigenetic regulation and its impact on human health.

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Dnmt Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Dnmt1 Antibody (H-12)

sc-271729mouse IgG1 κ1317-1616 (h)WB, IP, IF, IHC(P), ELISAm, r, h
70
(22)

Dnmt1 Antibody (D-9)

sc-514784mouse IgG11551-1572 (h)WB, IP, IF, ELISAm, r, h
2
(0)

Dnmt2 Antibody (D-9)

sc-365001mouse IgG1 κ121-391 (h)WB, IP, IF, ELISAm, r, h
13
(5)

Dnmt2 Antibody (A-7)

sc-271513mouse IgG2b κ121-391 (h)WB, IP, IF, ELISAm, r, h
5
(1)

Dnmt3a Antibody (C-12)

sc-365769mouse IgG2b κ42-67 (h)WB, IP, ELISAm, r, h
24
(12)

Dnmt3a Antibody (A-10)

sc-373905mouse IgG1 κ1-295 (h)WB, IP, IF, IHC(P), ELISAm, r, h
28
(4)

Dnmt3a Antibody (64B1446)

sc-52921mouse IgG1(m)WB, IP, IFm, r, h
3
(1)

Dnmt3a Antibody (64B814)

sc-56656mouse IgG1(m)WB, IP, IFm, r > h

new

(1)

Dnmt3b Antibody (G-9)

sc-376043mouse IgG1 κ1-230 (h)WB, IP, IF, ELISAm, r, h
35
(12)

Dnmt3b Antibody (2280C3a)

sc-81252mouse IgG2bInternal (h)WB, IP, FCMm, r, h
17
(7)

Dnmt3b Antibody (D-1)

sc-393279mouse IgG3 κ27-54 (h)WB, IP, IF, ELISAh
1
(1)

Dnmt3b Antibody (F-2)

sc-393845mouse IgG1 κ27-52 (h)WB, IP, IF, ELISAm, r, h
2
(1)

Dnmt3L Antibody (A-4)

sc-393603mouse IgG2a κ303-387 (h)WB, IP, IF, ELISAm, r, h
5
(5)

Dnmt siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Dnmt1 siRNA (h)

sc-35204hGene SilencingN/A
32
(2)

Dnmt1 siRNA (h2)

sc-156049hGene SilencingN/A
3
(0)

Dnmt1 shRNA Plasmid (h2)

sc-156049-SHhGene SilencingPuromycin
3
(0)

Dnmt1 shRNA (h2) Lentiviral Particles

sc-156049-VhGene SilencingPuromycin
3
(0)

Dnmt1 siRNA (m)

sc-35203mGene SilencingN/A
9
(0)

Dnmt1 shRNA Plasmid (m)

sc-35203-SHmGene SilencingPuromycin
9
(0)

Dnmt1 shRNA (m) Lentiviral Particles

sc-35203-VmGene SilencingPuromycin
9
(0)

Dnmt1 siRNA (r)

sc-270085rGene SilencingN/A
1
(0)

Dnmt1 shRNA Plasmid (r)

sc-270085-SHrGene SilencingPuromycin
1
(0)

Dnmt1 shRNA (r) Lentiviral Particles

sc-270085-VrGene SilencingPuromycin
1
(0)

Dnmt1 siRNA (bovine)

sc-270516bovineGene SilencingN/A
1
(0)

Dnmt1 shRNA Plasmid (bovine)

sc-270516-SHbovineGene SilencingPuromycin
1
(0)

Dnmt1 shRNA (bovine) Lentiviral Particles

sc-270516-VbovineGene SilencingPuromycin
1
(0)

Dnmt2 siRNA (h)

sc-35205hGene SilencingN/A
1
(0)

Dnmt2 shRNA Plasmid (h)

sc-35205-SHhGene SilencingPuromycin
1
(0)

Dnmt2 shRNA (h) Lentiviral Particles

sc-35205-VhGene SilencingPuromycin
1
(0)

Dnmt2 siRNA (m)

sc-35206mGene SilencingN/A0
(0)

Dnmt2 shRNA Plasmid (m)

sc-35206-SHmGene SilencingPuromycin0
(0)

Dnmt2 shRNA (m) Lentiviral Particles

sc-35206-VmGene SilencingPuromycin0
(0)

Dnmt3a siRNA (h)

sc-37757hGene SilencingN/A
13
(2)

Dnmt3a shRNA Plasmid (h)

sc-37757-SHhGene SilencingPuromycin
13
(2)

Dnmt3a shRNA (h) Lentiviral Particles

sc-37757-VhGene SilencingPuromycin
13
(2)

Dnmt3a siRNA (m)

sc-37758mGene SilencingN/A
3
(0)

Dnmt3a shRNA Plasmid (m)

sc-37758-SHmGene SilencingPuromycin
3
(0)

Dnmt3a shRNA (m) Lentiviral Particles

sc-37758-VmGene SilencingPuromycin
3
(0)

Dnmt3a siRNA (r)

sc-270087rGene SilencingN/A
1
(0)

Dnmt3a shRNA Plasmid (r)

sc-270087-SHrGene SilencingPuromycin
1
(0)

Dnmt3a shRNA (r) Lentiviral Particles

sc-270087-VrGene SilencingPuromycin
1
(0)

Dnmt3a siRNA (bovine)

sc-270517bovineGene SilencingN/A0
(0)

Dnmt3a shRNA Plasmid (bovine)

sc-270517-SHbovineGene SilencingPuromycin0
(0)

Dnmt3a shRNA (bovine) Lentiviral Particles

sc-270517-VbovineGene SilencingPuromycin0
(0)

Dnmt3b siRNA (h)

sc-37759hGene SilencingN/A
14
(1)

Dnmt3b shRNA Plasmid (h)

sc-37759-SHhGene SilencingPuromycin
14
(1)

Dnmt3b shRNA (h) Lentiviral Particles

sc-37759-VhGene SilencingPuromycin
14
(1)

Dnmt3b siRNA (m)

sc-37760mGene SilencingN/A
1
(0)

Dnmt3b shRNA Plasmid (m)

sc-37760-SHmGene SilencingPuromycin
1
(0)

Dnmt3b shRNA (m) Lentiviral Particles

sc-37760-VmGene SilencingPuromycin
1
(0)

Dnmt3b siRNA (r)

sc-270020rGene SilencingN/A
1
(0)

Dnmt3L siRNA (h)

sc-37761hGene SilencingN/A
1
(0)

Dnmt3L shRNA Plasmid (h)

sc-37761-SHhGene SilencingPuromycin
1
(0)

Dnmt3L shRNA (h) Lentiviral Particles

sc-37761-VhGene SilencingPuromycin
1
(0)

Dnmt3L siRNA (m)

sc-37762mGene SilencingN/A0
(0)

Dnmt3L shRNA Plasmid (m)

sc-37762-SHmGene SilencingPuromycin0
(0)

Dnmt3L shRNA (m) Lentiviral Particles

sc-37762-VmGene SilencingPuromycin0
(0)

Dnmt CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Dnmt1 CRISPR/Cas9 KO Plasmid (h2)

sc-400272-KO-2Gene Knockouth0
(0)

Dnmt1 CRISPR/Cas9 KO Plasmid (m)

sc-420033Gene Knockoutm0
(0)

Dnmt1 HDR Plasmid (m)

sc-420033-HDRHomology Directed Repairm0
(0)

Dnmt2 CRISPR/Cas9 KO Plasmid (h)

sc-402709Gene Knockouth0
(0)

Dnmt2 HDR Plasmid (h)

sc-402709-HDRHomology Directed Repairh0
(0)

Dnmt2 CRISPR/Cas9 KO Plasmid (m)

sc-420034Gene Knockoutm0
(0)

Dnmt3a CRISPR/Cas9 KO Plasmid (h)

sc-400323Gene Knockouth0
(0)

Dnmt3a HDR Plasmid (h)

sc-400323-HDRHomology Directed Repairh0
(0)

Dnmt3a CRISPR/Cas9 KO Plasmid (m)

sc-420035Gene Knockoutm0
(0)

Dnmt3a HDR Plasmid (m)

sc-420035-HDRHomology Directed Repairm0
(0)

Dnmt3b CRISPR/Cas9 KO Plasmid (m)

sc-420036Gene Knockoutm0
(0)

Dnmt3b HDR Plasmid (m)

sc-420036-HDRHomology Directed Repairm0
(0)

Dnmt3L CRISPR/Cas9 KO Plasmid (m)

sc-424871Gene Knockoutm0
(0)

Dnmt CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Dnmt1 Double Nickase Plasmid (h)

sc-400272-NICGene Knockouth0
(0)

Dnmt1 Double Nickase Plasmid (h2)

sc-400272-NIC-2Gene Knockouth0
(0)

Dnmt1 Double Nickase Plasmid (m)

sc-420033-NICGene Knockoutm0
(0)

Dnmt1 Double Nickase Plasmid (m2)

sc-420033-NIC-2Gene Knockoutm0
(0)

Dnmt2 Double Nickase Plasmid (h)

sc-402709-NICGene Knockouth0
(0)

Dnmt2 Double Nickase Plasmid (h2)

sc-402709-NIC-2Gene Knockouth0
(0)

Dnmt2 Double Nickase Plasmid (m)

sc-420034-NICGene Knockoutm0
(0)

Dnmt2 Double Nickase Plasmid (m2)

sc-420034-NIC-2Gene Knockoutm0
(0)

Dnmt3a Double Nickase Plasmid (h)

sc-400323-NICGene Knockouth0
(0)

Dnmt3a Double Nickase Plasmid (h2)

sc-400323-NIC-2Gene Knockouth0
(0)

Dnmt3a Double Nickase Plasmid (m)

sc-420035-NICGene Knockoutm0
(0)

Dnmt3a Double Nickase Plasmid (m2)

sc-420035-NIC-2Gene Knockoutm0
(0)

Dnmt3b Double Nickase Plasmid (h)

sc-400332-NICGene Knockouth0
(0)

Dnmt3b Double Nickase Plasmid (h2)

sc-400332-NIC-2Gene Knockouth0
(0)

Dnmt CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Dnmt1 CRISPR Activation Plasmid (h)

sc-400272-ACTGene Activationh0
(0)

Dnmt1 CRISPR Activation Plasmid (h2)

sc-400272-ACT-2Gene Activationh0
(0)

Dnmt1 CRISPR Activation Plasmid (m)

sc-420033-ACTGene Activationm0
(0)

Dnmt1 CRISPR Activation Plasmid (m2)

sc-420033-ACT-2Gene Activationm0
(0)

Dnmt1 Lentiviral Activation Particles (m)

sc-420033-LACGene Activationm0
(0)

Dnmt2 CRISPR Activation Plasmid (h)

sc-402709-ACTGene Activationh0
(0)

Dnmt2 CRISPR Activation Plasmid (h2)

sc-402709-ACT-2Gene Activationh0
(0)

Dnmt2 Lentiviral Activation Particles (h)

sc-402709-LACGene Activationh0
(0)

Dnmt2 Lentiviral Activation Particles (h2)

sc-402709-LAC-2Gene Activationh0
(0)

Dnmt2 CRISPR Activation Plasmid (m)

sc-420034-ACTGene Activationm0
(0)

Dnmt2 CRISPR Activation Plasmid (m2)

sc-420034-ACT-2Gene Activationm0
(0)

Dnmt3a CRISPR Activation Plasmid (m)

sc-420035-ACTGene Activationm0
(0)

Dnmt3b CRISPR Activation Plasmid (m)

sc-420036-ACTGene Activationm0
(0)

Dnmt3b CRISPR Activation Plasmid (m2)

sc-420036-ACT-2Gene Activationm0
(0)

Dnmt3L CRISPR Activation Plasmid (h)

sc-403892-ACTGene Activationh0
(0)