Dnmt3b Antibody (D-1): sc-393279
- Dnmt3b Antibody (D-1) is a mouse monoclonal IgG3 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 27-54 near the N-terminus of Dnmt3b of human origin
- recommended for detection of Dnmt3b of human origin by WB, IP, IF and ELISA
- See Dnmt3b (G-9): sc-376043 for Dnmt3b antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG3 BP-HRP is the preferred secondary detection reagent for Dnmt3b Antibody (D-1) for WB applications. This reagent is now offered in a bundle with Dnmt3b Antibody (D-1) (see ordering information below).
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Dnmt3b Antibody (D-1) is a mouse monoclonal IgG3 antibody that detects Dnmt3b in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Dnmt3b plays a crucial role in the regulation of gene expression during embryonic development by catalyzing the addition of methyl groups to cytosines in the CpG dinucleotide context, which is essential for establishing and maintaining epigenetic marks that influence cellular differentiation and identity. Dnmt3b is predominantly localized in the nucleus, where anti-Dnmt3b antibody (D-1) detects interactions with DNA and other regulatory proteins to modulate chromatin structure and accessibility, thereby impacting transcriptional activity. Proper functioning of Dnmt3b is vital, as aberrations in activity can lead to developmental disorders and contribute to the pathogenesis of various diseases, including cancer. Dnmt3b is part of a larger family of DNA methyltransferases, and unique expression patterns and regulatory mechanisms underscore Dnmt3b′s importance in epigenetic programming and cellular memory.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dnmt3b Antibody (D-1) | sc-393279 | 200 µg/ml | $316.00 | |||
Dnmt3b Antibody (D-1): m-IgG3 BP-HRP Bundle | sc-550488 | 200 µg Ab; 40 µg BP | $354.00 | |||
Dnmt3b (D-1) Neutralizing Peptide | sc-393279 P | 100 µg/0.5 ml | $68.00 |