Dnmt1 Antibody (D-9): sc-514784
- Dnmt1 Antibody (D-9) is a mouse monoclonal IgG1, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1551-1572 near the C-terminus of Dnmt1 of human origin
- recommended for detection of Dnmt1 of mouse, rat and human origin by WB, IP, IF and ELISA
- See Dnmt1 (H-12): sc-271729 for Dnmt1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Dnmt1 Antibody (D-9) for WB applications. These reagents are now offered in bundles with Dnmt1 Antibody (D-9) (see ordering information below).
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Dnmt1 Antibody (D-9) is a mouse monoclonal IgG1 antibody that detects DNA 5-cytosine methyltransferase 1 (Dnmt1) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Dnmt1 plays a crucial role in maintaining DNA methylation patterns, which are essential for regulating gene expression and cellular differentiation. Dnmt1 is primarily located in the nucleus, where Dnmt1 interacts with hemimethylated DNA to ensure faithful transmission of epigenetic information during DNA replication. The ability of Dnmt1 to recognize and bind to hemimethylated sites is vital for preserving methylation status of genes, thereby influencing developmental processes and cellular identity. Dysregulation of Dnmt1 has been implicated in various diseases, including cancer, making Dnmt1 a significant target for research into epigenetic therapies. anti-Dnmt1 antibody (D-9) is an invaluable tool for studying DNA methylation dynamics and impact on gene regulation across different biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dnmt1 Antibody (D-9) | sc-514784 | 200 µg/ml | $316.00 | |||
Dnmt1 Antibody (D-9): m-IgG Fc BP-HRP Bundle | sc-540993 | 200 µg Ab; 10 µg BP | $354.00 | |||
Dnmt1 Antibody (D-9): m-IgG1 BP-HRP Bundle | sc-542517 | 200 µg Ab; 20 µg BP | $354.00 | |||
Dnmt1 (D-9) Neutralizing Peptide | sc-514784 P | 100 µg/0.5 ml | $68.00 |