Dnmt3a Antibody (64B1446): sc-52921
- Dnmt3a Antibody (64B1446) is a mouse monoclonal IgG1, cited in 3 publications, provided at 50 µg/500 µl
- raised against recombinant Dnmt3a of mouse origin
- recommended for detection of Dnmt3a of mouse, rat and human origin by WB, IP and IF
- See Dnmt3a (C-12): sc-365769 for Dnmt3a antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Dnmt3a Antibody (64B1446). This work is in progress.
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Dnmt3a Antibody (64B1446) is a mouse monoclonal IgG1 antibody that detects Dnmt3a in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Dnmt3a plays a crucial role in regulating gene expression during development by catalyzing cytosine methylation within CpG dinucleotides, which is essential for maintaining genomic stability and proper cellular function. Dnmt3a is predominantly expressed in embryonic stem cells, where anti-Dnmt3a antibody (64B1446) can detect its involvement in establishing and maintaining DNA methylation patterns vital for cell differentiation and development. Adding methyl groups to DNA influences gene silencing and impacts processes such as genomic imprinting and X-chromosome inactivation, making Dnmt3a a key player in epigenetic regulation. Dnmt3a interacts with various cofactors and other proteins that modulate methylation activity, highlighting Dnmt3a′s importance in epigenetic modifications and cellular identity. Dnmt3a monoclonal antibody (64B1446) serves as an invaluable tool for researchers studying DNA methylation mechanisms and their implications in development and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dnmt3a Antibody (64B1446) | sc-52921 | 50 µg/500 µl | $316.00 |