Dnmt3a Antibody (64B814): sc-56656
- Dnmt3a Antibody (64B814) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against recombinant Dnmt3a of mouse origin
- recommended for detection of Dnmt3a of mouse, rat and, to a lesser extent, human origin by WB, IP and IF
- See Dnmt3a (C-12): sc-365769 for Dnmt3a antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Dnmt3a Antibody (64B814). This work is in progress.
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Dnmt3a Antibody (64B814) is a mouse monoclonal IgG1 antibody that detects Dnmt3a in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Dnmt3a plays a crucial role in the regulation of gene expression by catalyzing the addition of methyl groups to cytosines in the CpG dinucleotide context, which is essential for establishing and maintaining epigenetic marks during development and cellular differentiation. Dnmt3a is predominantly localized in the nucleus, where anti-Dnmt3a antibody (64B814) can detect interactions with DNA and other regulatory proteins that influence chromatin structure and gene accessibility. The proper functioning of Dnmt3a is vital for normal embryonic development, and dysregulation of its activity has been implicated in various diseases, including cancer. Dnmt3a works in concert with other DNA methyltransferases, such as Dnmt1 and Dnmt3b, to ensure the fidelity of DNA methylation patterns, which are critical for cellular identity and function. Dnmt3a monoclonal antibody (64B814) provides a reliable tool for researchers investigating the complex mechanisms of epigenetic regulation and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dnmt3a Antibody (64B814) | sc-56656 | 100 µg/ml | $316.00 |