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Dnmt3b Antibody (F-2) is a mouse monoclonal IgG1 antibody that detects Dnmt3b in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Dnmt3b plays a crucial role in regulating gene expression during embryonic development by catalyzing methyl group addition to cytosines within CpG dinucleotides, thereby influencing chromatin structure and gene silencing. Dnmt3b (F-2) antibody targets one of the key enzymes responsible for de novo methylation, which establishes new methylation patterns essential for cellular differentiation and development. Dnmt3b is predominantly expressed in embryonic stem cells, working alongside Dnmt3a to ensure proper DNA methylation, thus facilitating pluripotency maintenance and transition to differentiated states. Anti-Dnmt3b antibody (F-2) serves as an invaluable tool for studying gene expression and epigenetic modifications, as Dnmt3b interacts with various transcription factors and regulatory proteins in developmental biology and disease contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dnmt3b Antibody (F-2) | sc-393845 | 200 µg/ml | $316.00 | |||
Dnmt3b Antibody (F-2): m-IgG Fc BP-HRP Bundle | sc-538322 | 200 µg Ab; 10 µg BP | $354.00 | |||
Dnmt3b Antibody (F-2): m-IgGκ BP-HRP Bundle | sc-535906 | 200 µg Ab; 40 µg BP | $354.00 | |||
Dnmt3b Antibody (F-2): m-IgG1 BP-HRP Bundle | sc-545640 | 200 µg Ab; 20 µg BP | $354.00 | |||
Dnmt3b (F-2) Neutralizing Peptide | sc-393845 P | 100 µg/0.5 ml | $68.00 |