Date published: 2026-5-4

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spectrin Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of spectrin monoclonal antibodies for research in cell structure and function. Spectrin monoclonal antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Spectrin is a crucial cytoskeletal protein that plays a significant role in maintaining the integrity and shape of cells, particularly in red blood cells and neurons. It forms a mesh-like structure beneath the plasma membrane, providing mechanical support and facilitating cellular processes such as signaling and transport. Understanding spectrin function is essential for elucidating various physiological and pathological conditions, including hereditary spherocytosis and neurodegenerative diseases. Spectrin research has revealed important insights into membrane organization and cellular architecture. Investigating spectrin helps researchers better understand cytoskeletal dynamics and membrane protein interactions. Current studies continue to uncover new aspects of spectrin's role in cellular health and disease. Santa Cruz Biotechnology monoclonal antibodies for spectrin research support scientists worldwide in advancing our understanding of cellular biology and disease mechanisms.

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spectrin Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

spectrin α I Antibody (B-12)

sc-271130mouse IgG1 κ541-650 (h)WB, IP, IF, IHC(P), ELISAh
3
(5)

spectrin Antibody (RG/26)

sc-53444mouse IgG2a κ(h)WB, IP, IF, IHC(P)m, r, h
4
(2)

spectrin α I Antibody (IID2)

sc-53900mouse IgG κN-Terminal (h)WB, IP, IFm, r, h and canine
1
(2)

spectrin α II Antibody (C-3)

sc-48382mouse IgG1 κ2368-2472 (h)WB, IP, IF, IHC(P), ELISAm, r, h
42
(13)

spectrin α II Antibody (C-11)

sc-46696mouse IgG1 κ2368-2472 (h)WB, IP, IF, IHC(P), ELISAm, r, h
31
(11)

spectrin α II Antibody (B-2)

sc-376849mouse IgG1 κ2431-2460 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(3)

spectrin β I Antibody (B-1)

sc-374309mouse IgG1 κ2111-2137 (h)WB, IP, IF, ELISAm, r, h
3
(3)

spectrin β I Antibody (4C3)

sc-58851mouse IgG1(h)WB, IP, IFm, r, h

new

(1)

spectrin β I Antibody (A-12)

sc-374308mouse IgG2a κ2111-2137 (h)WB, IP, IF, ELISAm, r, h

new

(1)

spectrin β I Antibody (B-2)

sc-377437mouse IgG3 κ2-29 (h)WB, IP, IF, ELISAm, r, h

new

(1)

spectrin β I Antibody (D-6)

sc-376859mouse IgG1 κN-Terminal (h)WB, IP, IF, ELISAm, r, h

new

(1)

spectrin β I Antibody (VD4)

sc-53901mouse IgG2b κ(h)WB, IP, IFm, r, h and canine
2
(1)

spectrin β I Antibody (6D772)

sc-73053mouse IgG1(h)WB, IP, IFm, r, h

new

(1)

spectrin β II Antibody (F-7)

sc-515592mouse IgG1 κ2341-2363 (h)WB, IP, IF, ELISAm, r, h
2
(1)

spectrin β II Antibody (42)

sc-136074mouse IgG1 κ2101-2189 (h)WB, IP, IFm, r, h and canine
11
(5)

spectrin β II Antibody (F-11)

sc-376487mouse IgG1 κ2086-2210 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(3)

spectrin β II Antibody (G-10)

sc-374126mouse IgG1 κ2229-2261 (h)WB, IP, IF, ELISAm, r, h

new

(2)

spectrin β II Antibody (H-5)

sc-374125mouse IgG3 κ2229-2261 (h)WB, IP, IF, ELISAm, r, h

new

(3)

spectrin β III Antibody (A-8)

sc-515737mouse IgG1 κ2-22 (h)WB, IP, IF, ELISAm, r, h
1
(2)

spectrin β III Antibody (4D9)

sc-293284mouse IgG3 κ643-720 (h)WB, IP, ELISAm, r, h

new

(0)

spectrin β IV Antibody (F-5)

sc-398506mouse IgG1 κ1661-1745 (h)WB, IP, IF, ELISAm, r, h

new

(1)

spectrin β IV Antibody (D-7)

sc-514744mouse IgM κ2351-2369 (h)WB, IP, IF, ELISAm, r, h
1
(0)

spectrin CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

spectrin α I CRISPR/Cas9 KO Plasmid (h)

sc-403563hGene KnockoutGFP0
(0)

spectrin α II CRISPR/Cas9 KO Plasmid (h)

sc-400910hGene KnockoutGFP0
(0)

spectrin α II HDR Plasmid (h)

sc-400910-HDRhHomology Directed RepairPuromycin0
(0)

spectrin β II CRISPR/Cas9 KO Plasmid (h)

sc-401818hGene KnockoutGFP0
(0)

spectrin β II HDR Plasmid (h)

sc-401818-HDRhHomology Directed RepairPuromycin0
(0)

spectrin β II Double Nickase Plasmid (h)

sc-401818-NIChGene KnockoutPuromycin0
(0)

spectrin β II Double Nickase Plasmid (h2)

sc-401818-NIC-2hGene KnockoutPuromycin0
(0)

spectrin β V HDR Plasmid (h)

sc-407646-HDRhHomology Directed RepairPuromycin0
(0)

spectrin CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

spectrin α I CRISPR Activation Plasmid (h)

sc-403563-ACThGene ActivationPuro, Blast, Hygro0
(0)

spectrin α II CRISPR Activation Plasmid (h)

sc-400910-ACThGene ActivationPuro, Blast, Hygro0
(0)

spectrin α II CRISPR Activation Plasmid (h2)

sc-400910-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

spectrin β I CRISPR Activation Plasmid (h)

sc-402738-ACThGene ActivationPuro, Blast, Hygro0
(0)

spectrin β I CRISPR Activation Plasmid (h2)

sc-402738-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

spectrin β III CRISPR Activation Plasmid (h)

sc-402980-ACThGene ActivationPuro, Blast, Hygro0
(0)

spectrin siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

spectrin α I siRNA (h)

sc-43430hGene SilencingN/A0
(0)

spectrin α I shRNA Plasmid (h)

sc-43430-SHhGene SilencingPuromycin0
(0)

spectrin α I shRNA (h) Lentiviral Particles

sc-43430-VhGene SilencingPuromycin0
(0)

spectrin α I siRNA (m)

sc-43431mGene SilencingN/A0
(0)

spectrin α I shRNA Plasmid (m)

sc-43431-SHmGene SilencingPuromycin0
(0)

spectrin α I shRNA (m) Lentiviral Particles

sc-43431-VmGene SilencingPuromycin0
(0)

spectrin α II siRNA (h)

sc-36549hGene SilencingN/A
1
(0)

spectrin α II shRNA Plasmid (h)

sc-36549-SHhGene SilencingPuromycin
1
(0)

spectrin α II shRNA (h) Lentiviral Particles

sc-36549-VhGene SilencingPuromycin
1
(0)

spectrin α II siRNA (m)

sc-36550mGene SilencingN/A0
(0)

spectrin α II shRNA Plasmid (m)

sc-36550-SHmGene SilencingPuromycin0
(0)

spectrin α II shRNA (m) Lentiviral Particles

sc-36550-VmGene SilencingPuromycin0
(0)

spectrin β I siRNA (h)

sc-36547hGene SilencingN/A0
(0)

spectrin β I siRNA (m)

sc-36548mGene SilencingN/A
2
(0)

spectrin β II siRNA (h)

sc-36551hGene SilencingN/A
4
(0)

spectrin β II shRNA Plasmid (h)

sc-36551-SHhGene SilencingPuromycin
4
(0)

spectrin β II shRNA (h) Lentiviral Particles

sc-36551-VhGene SilencingPuromycin
4
(0)

spectrin β II siRNA (m2)

sc-270043mGene SilencingN/A0
(0)

spectrin β II shRNA Plasmid (m2)

sc-270043-SHmGene SilencingPuromycin0
(0)

spectrin β II shRNA (m2) Lentiviral Particles

sc-270043-VmGene SilencingPuromycin0
(0)

spectrin β III siRNA (h)

sc-43432hGene SilencingN/A0
(0)

spectrin β III shRNA Plasmid (h)

sc-43432-SHhGene SilencingPuromycin0
(0)

spectrin β III shRNA (h) Lentiviral Particles

sc-43432-VhGene SilencingPuromycin0
(0)

spectrin β III siRNA (m)

sc-43433mGene SilencingN/A0
(0)

spectrin β III shRNA Plasmid (m)

sc-43433-SHmGene SilencingPuromycin0
(0)

spectrin β III shRNA (m) Lentiviral Particles

sc-43433-VmGene SilencingPuromycin0
(0)

spectrin β IV siRNA (h)

sc-97805hGene SilencingN/A0
(0)

spectrin β IV shRNA Plasmid (h)

sc-97805-SHhGene SilencingPuromycin0
(0)

spectrin β IV shRNA (h) Lentiviral Particles

sc-97805-VhGene SilencingPuromycin0
(0)

spectrin β IV siRNA (m)

sc-153737mGene SilencingN/A0
(0)

spectrin β IV shRNA Plasmid (m)

sc-153737-SHmGene SilencingPuromycin0
(0)

spectrin β IV shRNA (m) Lentiviral Particles

sc-153737-VmGene SilencingPuromycin0
(0)

spectrin β V siRNA (h)

sc-89958hGene SilencingN/A0
(0)

spectrin β V shRNA Plasmid (h)

sc-89958-SHhGene SilencingPuromycin0
(0)

spectrin β V shRNA (h) Lentiviral Particles

sc-89958-VhGene SilencingPuromycin0
(0)

spectrin β 1 shRNA Plasmid (h)

sc-36547-SHhGene SilencingPuromycin0
(0)

spectrin β 1 shRNA (h) Lentiviral Particles

sc-36547-VhGene SilencingPuromycin0
(0)

spectrin β 1 shRNA Plasmid (m)

sc-36548-SHmGene SilencingPuromycin
2
(0)

spectrin β 1 shRNA (m) Lentiviral Particles

sc-36548-VmGene SilencingPuromycin
2
(0)