spectrin α I Antibody (IID2): sc-53900
- spectrin α I Antibody (IID2) is a mouse monoclonal IgG κ, cited in 1 publications, provided at 200 µg/ml
- raised against purified erythrocyte spectrin αI of human origin, with epitope mapping near the N-terminus
- Anti-spectrin alpha I Antibody (IID2) is recommended for detection of spectrin α I of mouse, rat, human and canine origin by WB, IP and IF
- Anti-spectrin alpha I Antibody (IID2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for spectrin α I Antibody (IID2) for WB applications. This reagent is now offered in a bundle with spectrin α I Antibody (IID2) (see ordering information below).
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SEE ALSO...
Spectrin α I Antibody (IID2) is a mouse monoclonal IgG2a antibody that detects spectrin α I in mouse, rat, human, and canine samples through western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF) applications. Anti-spectrin α I antibody (IID2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Spectrin α I plays a crucial role in maintaining the structural integrity and stability of the plasma membrane in erythrocytes, as a key component of the cytoskeletal framework. Spectrin α I is primarily located beneath the plasma membrane, where spectrin α I forms a mesh-like structure that supports cell shape and facilitates deformability during circulation. Proper functioning of spectrin α I is vital for red blood cells, as defects can lead to various hematological disorders, including hereditary spherocytosis and elliptocytosis, which are characterized by abnormal red blood cell shapes. Spectrin α I monoclonal antibody (IID2) enables researchers to gain valuable insights into cytoskeletal dynamics and membrane organization of erythrocytes, contributing to a better understanding of related pathologies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
spectrin α I Antibody (IID2) | sc-53900 | 200 µg/ml | $322.00 | |||
spectrin α I Antibody (IID2): m-IgG Fc BP-HRP Bundle | sc-525620 | 200 µg Ab; 10 µg BP | $361.00 | |||
spectrin α I Antibody (IID2) AC | sc-53900 AC | 500 µg/ml, 25% agarose | $424.00 | |||
spectrin α I Antibody (IID2) HRP | sc-53900 HRP | 200 µg/ml | $322.00 | |||
spectrin α I Antibody (IID2) FITC | sc-53900 FITC | 200 µg/ml | $336.00 | |||
spectrin α I Antibody (IID2) PE | sc-53900 PE | 200 µg/ml | $349.00 | |||
spectrin α I Antibody (IID2) Alexa Fluor® 488 | sc-53900 AF488 | 200 µg/ml | $364.00 | |||
spectrin α I Antibody (IID2) Alexa Fluor® 546 | sc-53900 AF546 | 200 µg/ml | $364.00 | |||
spectrin α I Antibody (IID2) Alexa Fluor® 594 | sc-53900 AF594 | 200 µg/ml | $364.00 | |||
spectrin α I Antibody (IID2) Alexa Fluor® 647 | sc-53900 AF647 | 200 µg/ml | $364.00 | |||
spectrin α I Antibody (IID2) Alexa Fluor® 680 | sc-53900 AF680 | 200 µg/ml | $364.00 | |||
spectrin α I Antibody (IID2) Alexa Fluor® 790 | sc-53900 AF790 | 200 µg/ml | $364.00 |