Anti-spectrin β III Antibody (A-8) is a mouse monoclonal IgG1 (kappa light chain) spectrin β III antibody provided at 200 µg/ml
specific for an epitope mapping between amino acids 2-22 at the N-terminus of spectrin β III of human origin
Anti-spectrin beta III Antibody (A-8) is recommended for detection of spectrin β III of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-spectrin beta III Antibody (A-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of spectrin β III (A-8): sc-515737.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for spectrin β III Antibody (A-8) for WB applications. These reagents are now offered in bundles with spectrin β III Antibody (A-8) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
spectrin β III Antibody (A-8) is a high quality monoclonal spectrin beta III antibody (also designated SPTBN2 antibody or Spectrin beta-3 antibody) suitable for the detection of the spectrin beta III protein of mouse, rat and human origin. spectrin β III Antibody (A-8) is available as both the non-conjugated anti-spectrin beta III antibody form, as well as multiple conjugated forms of anti-spectrin beta III antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Spectrin α and spectrin β are present in erythrocytes, whereas spectrin α II (also designated fodrin α) and spectrin β I (also designated fodrin β) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin β III is highly homologous to both spectrin β I and spectrin β II. Western blot analysis shows that spectrin β III migrates at a higher molecular mass than predicted in the kidney. Spectrin β III is highly expressed in brain, kidney, pancreas, and liver, and at lower levels in lung and placenta. Specifically, spectrin β III constitutes a major component of the Golgi and vesicular membrane skeletons.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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