Date published: 2026-7-9

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PTP Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of PTP Antibodies for the study of protein tyrosine phosphatases. PTP Antibodies are effective tools in various research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Protein tyrosine phosphatases regulate cellular processes such as growth, differentiation, and metabolism by removing phosphate groups from tyrosine residues on proteins. Dysregulation of protein tyrosine phosphatases is often implicated in various diseases, including cancer and autoimmune disorders, making them significant targets for therapeutic intervention. Understanding the function and regulation of protein tyrosine phosphatases is essential for advancing knowledge of cellular signaling pathways. Researchers worldwide rely on protein tyrosine phosphatases to uncover new insights into disease mechanisms and potential treatments. PTP monoclonal antibodies enable detailed investigation of phosphatase activity in diverse biological systems. The extensive selection of monoclonal antibodies from Santa Cruz Biotechnology empowers researchers to make meaningful contributions to scientific understanding of cellular regulation and disease processes.

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PTP Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PTP IA-2 Antibody (A-5)

sc-390101mouse IgG2a κ723-763 (h)WB, IP, IF, ELISAm, r, h
1
(1)

PTP IA-2 Antibody (98/4H6)

sc-130570mouse IgG1 κ602-979 (h)WB, IP, IF, IHC(P)m, r, h

new

(2)

PTP IA-2 Antibody (AFT38)

sc-135672mouse IgG1N/AWB, IP, ELISAh

new

(2)

PTP IA-2β Antibody (B-4)

sc-393922mouse IgG2a κ61-360 (h)WB, IP, IF, ELISAh

new

(1)

PTP-H1 Antibody (H-6)

sc-515181mouse IgG2a κ371-510 (h)WB, IP, IF, ELISAh
5
(4)

PTPε Antibody (G-2)

sc-515692mouse IgG3678-699 (h)WB, IP, IF, ELISAm, r, h

new

(1)

PTPκ Antibody (H-3)

sc-374315mouse IgG2b κ27-101 (h)WB, IP, IF, ELISAm, r, h
6
(4)

PTPµ Antibody (SBK10)

sc-65228mouse IgG1 κ42-60 (h)WB, IPm, r, h
2
(3)

PTPµ Antibody (BK2)

sc-33651mouse IgG2a κextracellular (h)WB, IP, IFm, r, h
2
(1)

PTPµ Antibody (SK15)

sc-56959mouse IgG1 κ(h)WB, IPm, r, h
2
(1)

PTPψ Antibody (E-2)

sc-393104mouse IgG1 κ1-96 (h)WB, IP, IF, ELISAh

new

(1)

PTPσ Antibody (SS-8)

sc-100419mouse IgG2b κ1-129 (h)WB, IP, ELISAh
2
(2)

PTPζ Antibody (122.2)

sc-33664mouse IgM κ(r)WB, IP, IF, IHC(P)m, r, h
9
(3)

PTP1B Antibody (D-4)

sc-133259mouse IgG1 κ301-435 (h)WB, IP, IF, IHC(P), ELISAh
16
(13)

PTP1B Antibody (B-9)

sc-133115mouse IgG2b κ301-435 (h)WB, IP, IF, ELISAh

new

(2)

PTP1B Antibody (H-9)

sc-133258mouse IgG1 κ301-435 (h)WB, IP, IF, IHC(P), ELISAh

new

(5)

PTP siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PTPβ siRNA (h)

sc-44051hGene SilencingN/A
1
(0)

PTPβ shRNA Plasmid (h)

sc-44051-SHhGene SilencingPuromycin
1
(0)

PTPβ shRNA (h) Lentiviral Particles

sc-44051-VhGene SilencingPuromycin
1
(0)

PTPβ siRNA (m)

sc-45976mGene SilencingN/A0
(0)

PTPβ shRNA Plasmid (m)

sc-45976-SHmGene SilencingPuromycin0
(0)

PTPβ shRNA (m) Lentiviral Particles

sc-45976-VmGene SilencingPuromycin0
(0)

PTPδ siRNA (h)

sc-44052hGene SilencingN/A0
(0)

PTPδ shRNA Plasmid (h)

sc-44052-SHhGene SilencingPuromycin0
(0)

PTPδ shRNA (h) Lentiviral Particles

sc-44052-VhGene SilencingPuromycin0
(0)

PTPδ siRNA (m)

sc-155951mGene SilencingN/A0
(0)

PTPδ shRNA Plasmid (m)

sc-155951-SHmGene SilencingPuromycin0
(0)

PTPδ shRNA (m) Lentiviral Particles

sc-155951-VmGene SilencingPuromycin0
(0)

PTPε siRNA (h)

sc-44054hGene SilencingN/A
2
(0)

PTPε shRNA Plasmid (h)

sc-44054-SHhGene SilencingPuromycin
2
(0)

PTPε shRNA (h) Lentiviral Particles

sc-44054-VhGene SilencingPuromycin
2
(0)

PTPε siRNA (m)

sc-152582mGene SilencingN/A0
(0)

PTPε shRNA Plasmid (m)

sc-152582-SHmGene SilencingPuromycin0
(0)

PTPε shRNA (m) Lentiviral Particles

sc-152582-VmGene SilencingPuromycin0
(0)

PTPγ siRNA (h)

sc-44049hGene SilencingN/A0
(0)

PTPγ shRNA Plasmid (h)

sc-44049-SHhGene SilencingPuromycin0
(0)

PTPγ shRNA (h) Lentiviral Particles

sc-44049-VhGene SilencingPuromycin0
(0)

PTPγ siRNA (m)

sc-155950mGene SilencingN/A0
(0)

PTPγ shRNA Plasmid (m)

sc-155950-SHmGene SilencingPuromycin0
(0)

PTPγ shRNA (m) Lentiviral Particles

sc-155950-VmGene SilencingPuromycin0
(0)

PTPκ siRNA (h)

sc-44050hGene SilencingN/A0
(0)

PTPκ shRNA Plasmid (h)

sc-44050-SHhGene SilencingPuromycin0
(0)

PTPκ shRNA (h) Lentiviral Particles

sc-44050-VhGene SilencingPuromycin0
(0)

PTPκ siRNA (m)

sc-155948mGene SilencingN/A0
(0)

PTPκ shRNA Plasmid (m)

sc-155948-SHmGene SilencingPuromycin0
(0)

PTPκ shRNA (m) Lentiviral Particles

sc-155948-VmGene SilencingPuromycin0
(0)

PTPμ siRNA (h)

sc-44055hGene SilencingN/A0
(0)

PTPμ shRNA Plasmid (h)

sc-44055-SHhGene SilencingPuromycin0
(0)

PTPμ shRNA (h) Lentiviral Particles

sc-44055-VhGene SilencingPuromycin0
(0)

PTPμ siRNA (m)

sc-45947mGene SilencingN/A0
(0)

PTPμ shRNA Plasmid (m)

sc-45947-SHmGene SilencingPuromycin0
(0)

PTPμ shRNA (m) Lentiviral Particles

sc-45947-VmGene SilencingPuromycin0
(0)

PTPψ siRNA (h)

sc-62910hGene SilencingN/A
1
(0)

PTPψ siRNA (m)

sc-62911mGene SilencingN/A0
(0)

PTPρ siRNA (h)

sc-62908hGene SilencingN/A0
(0)

PTPρ siRNA (m)

sc-62909mGene SilencingN/A0
(0)

PTPσ siRNA (h)

sc-44056hGene SilencingN/A0
(0)

PTPσ shRNA Plasmid (h)

sc-44056-SHhGene SilencingPuromycin0
(0)

PTPσ shRNA (h) Lentiviral Particles

sc-44056-VhGene SilencingPuromycin0
(0)

PTPσ siRNA (m)

sc-77403mGene SilencingN/A
1
(0)

PTPσ shRNA Plasmid (m)

sc-77403-SHmGene SilencingPuromycin
1
(0)

PTPσ shRNA (m) Lentiviral Particles

sc-77403-VmGene SilencingPuromycin
1
(0)

PTPζ siRNA (h)

sc-44048hGene SilencingN/A
1
(0)

PTPζ shRNA Plasmid (h)

sc-44048-SHhGene SilencingPuromycin
1
(0)

PTPζ shRNA (h) Lentiviral Particles

sc-44048-VhGene SilencingPuromycin
1
(0)

PTPζ siRNA (m)

sc-44970mGene SilencingN/A0
(0)

PTPζ shRNA Plasmid (m)

sc-44970-SHmGene SilencingPuromycin0
(0)

PTPζ shRNA (m) Lentiviral Particles

sc-44970-VmGene SilencingPuromycin0
(0)

PTPr shRNA Plasmid (h)

sc-62908-SHhGene SilencingPuromycin0
(0)

PTPr shRNA (h) Lentiviral Particles

sc-62908-VhGene SilencingPuromycin0
(0)

PTPr shRNA Plasmid (m)

sc-62909-SHmGene SilencingPuromycin0
(0)

PTPr shRNA (m) Lentiviral Particles

sc-62909-VmGene SilencingPuromycin0
(0)

PTPRQ siRNA (m)

sc-45263mGene SilencingN/A0
(0)

PTPRQ shRNA Plasmid (m)

sc-45263-SHmGene SilencingPuromycin0
(0)

PTPRQ shRNA (m) Lentiviral Particles

sc-45263-VmGene SilencingPuromycin0
(0)

PTPy shRNA Plasmid (h)

sc-62910-SHhGene SilencingPuromycin
1
(0)

PTPy shRNA (h) Lentiviral Particles

sc-62910-VhGene SilencingPuromycin
1
(0)

PTPy shRNA Plasmid (m)

sc-62911-SHmGene SilencingPuromycin0
(0)

PTPy shRNA (m) Lentiviral Particles

sc-62911-VmGene SilencingPuromycin0
(0)

PTP-H1 siRNA (h)

sc-44053hGene SilencingN/A0
(0)

PTP-H1 shRNA Plasmid (h)

sc-44053-SHhGene SilencingPuromycin0
(0)

PTP-H1 shRNA (h) Lentiviral Particles

sc-44053-VhGene SilencingPuromycin0
(0)

PTP-H1 siRNA (m)

sc-152580mGene SilencingN/A0
(0)

PTP-H1 shRNA Plasmid (m)

sc-152580-SHmGene SilencingPuromycin0
(0)

PTP-H1 shRNA (m) Lentiviral Particles

sc-152580-VmGene SilencingPuromycin0
(0)

PTP1B siRNA (h)

sc-36328hGene SilencingN/A
5
(0)

PTP1B shRNA Plasmid (h)

sc-36328-SHhGene SilencingPuromycin
5
(0)

PTP1B shRNA (h) Lentiviral Particles

sc-36328-VhGene SilencingPuromycin
5
(0)

PTP1B siRNA (m)

sc-36329mGene SilencingN/A
3
(0)

PTP1B shRNA Plasmid (m)

sc-36329-SHmGene SilencingPuromycin
3
(0)

PTP1B shRNA (m) Lentiviral Particles

sc-36329-VmGene SilencingPuromycin
3
(0)

PTP1B siRNA (r)

sc-270525rGene SilencingN/A0
(0)

PTP1B shRNA Plasmid (r)

sc-270525-SHrGene SilencingPuromycin0
(0)

PTP1B shRNA (r) Lentiviral Particles

sc-270525-VrGene SilencingPuromycin0
(0)

PTP IA-2 siRNA (h)

sc-62902hGene SilencingN/A0
(0)

PTP IA-2 shRNA Plasmid (h)

sc-62902-SHhGene SilencingPuromycin0
(0)

PTP IA-2 shRNA (h) Lentiviral Particles

sc-62902-VhGene SilencingPuromycin0
(0)

PTP IA-2 siRNA (m)

sc-62903mGene SilencingN/A0
(0)

PTP IA-2 shRNA Plasmid (m)

sc-62903-SHmGene SilencingPuromycin0
(0)

PTP IA-2 shRNA (m) Lentiviral Particles

sc-62903-VmGene SilencingPuromycin0
(0)

PTP IA-2β siRNA (h)

sc-106910hGene SilencingN/A0
(0)

PTP IA-2β shRNA Plasmid (h)

sc-106910-SHhGene SilencingPuromycin0
(0)

PTP IA-2β shRNA (h) Lentiviral Particles

sc-106910-VhGene SilencingPuromycin0
(0)

PTP CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

PTPβ CRISPR/Cas9 KO Plasmid (h)

sc-402100Gene Knockouth0
(0)

PTPβ CRISPR/Cas9 KO Plasmid (m)

sc-422516Gene Knockoutm0
(0)

PTPβ HDR Plasmid (m)

sc-422516-HDRHomology Directed Repairm0
(0)

PTPδ CRISPR/Cas9 KO Plasmid (m)

sc-422519Gene Knockoutm0
(0)

PTPδ HDR Plasmid (m)

sc-422519-HDRHomology Directed Repairm0
(0)

PTPε CRISPR/Cas9 KO Plasmid (h)

sc-405606Gene Knockouth0
(0)

PTPε CRISPR/Cas9 KO Plasmid (m)

sc-422520Gene Knockoutm0
(0)

PTPε HDR Plasmid (m)

sc-422520-HDRHomology Directed Repairm0
(0)

PTPγ CRISPR/Cas9 KO Plasmid (m)

sc-422522Gene Knockoutm0
(0)

PTPγ HDR Plasmid (m)

sc-422522-HDRHomology Directed Repairm0
(0)

PTPκ CRISPR/Cas9 KO Plasmid (h)

sc-402287Gene Knockouth0
(0)

PTPκ HDR Plasmid (h)

sc-402287-HDRHomology Directed Repairh0
(0)

PTPσ CRISPR/Cas9 KO Plasmid (h)

sc-402631Gene Knockouth0
(0)

PTPσ HDR Plasmid (h)

sc-402631-HDRHomology Directed Repairh0
(0)

PTPζ CRISPR/Cas9 KO Plasmid (h)

sc-401775Gene Knockouth0
(0)

PTPζ HDR Plasmid (h)

sc-401775-HDRHomology Directed Repairh0
(0)

PTP-H1 CRISPR/Cas9 KO Plasmid (h)

sc-404194Gene Knockouth0
(0)

PTP1B CRISPR/Cas9 KO Plasmid (h)

sc-400732Gene Knockouth0
(0)

PTP1B HDR Plasmid (h)

sc-400732-HDRHomology Directed Repairh0
(0)

PTP1B CRISPR/Cas9 KO Plasmid (m)

sc-422502Gene Knockoutm0
(0)

PTP1B HDR Plasmid (m)

sc-422502-HDRHomology Directed Repairm0
(0)

PTP IA-2 CRISPR/Cas9 KO Plasmid (h)

sc-406833Gene Knockouth0
(0)

PTP IA-2 HDR Plasmid (h)

sc-406833-HDRHomology Directed Repairh0
(0)

PTP CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

PTP1B Double Nickase Plasmid (h)

sc-400732-NICGene Knockouth0
(0)

PTP1B Double Nickase Plasmid (h2)

sc-400732-NIC-2Gene Knockouth0
(0)

PTP1B Double Nickase Plasmid (m)

sc-422502-NICGene Knockoutm0
(0)

PTP CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

PTPκ CRISPR Activation Plasmid (h)

sc-402287-ACTGene Activationh0
(0)

PTPκ CRISPR Activation Plasmid (h2)

sc-402287-ACT-2Gene Activationh0
(0)

PTPκ Lentiviral Activation Particles (h)

sc-402287-LACGene Activationh0
(0)

PTPμ CRISPR Activation Plasmid (h)

sc-403126-ACTGene Activationh0
(0)

PTPσ CRISPR Activation Plasmid (h)

sc-402631-ACTGene Activationh0
(0)

PTPσ CRISPR Activation Plasmid (h2)

sc-402631-ACT-2Gene Activationh0
(0)

PTPσ CRISPR Activation Plasmid (m)

sc-422531-ACTGene Activationm0
(0)

PTPσ Lentiviral Activation Particles (m)

sc-422531-LACGene Activationm0
(0)

PTPζ CRISPR Activation Plasmid (h)

sc-401775-ACTGene Activationh0
(0)

PTP1B CRISPR Activation Plasmid (h)

sc-400732-ACTGene Activationh0
(0)

PTP1B Lentiviral Activation Particles (h)

sc-400732-LACGene Activationh0
(0)

PTP IA-2β CRISPR Activation Plasmid (h)

sc-404896-ACTGene Activationh0
(0)