Date published: 2025-10-10

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PTP1B Antibodies

Santa Cruz Biotechnology features a diverse variety of PTP1B monoclonal antibodies for research focused on understanding Protein Tyrosine Phosphatase 1B (PTP1B) in various biological processes. PTP1B monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PTP1B is a critical enzyme involved in the regulation of insulin signaling and plays a significant role in glucose homeostasis. Dysregulation of PTP1B has been implicated in metabolic disorders, including obesity and type 2 diabetes, making it a key target for therapeutic intervention. Research utilizing PTP1B monoclonal antibodies can provide valuable insights into the mechanisms underlying these conditions. PTP1B monoclonal antibodies enable researchers to investigate cellular signaling pathways with precision and reliability. Studying PTP1B expression patterns and interactions helps advance understanding of metabolic regulation and potential therapeutic strategies. Research conducted with Santa Cruz Biotechnology monoclonal antibodies contributes to advancing scientific knowledge in metabolic disease research and therapeutic development.

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PTP1B Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PTP1B Antibody (D-4)

sc-133259mouse IgG1 κ301-435 (h)WB, IP, IF, IHC(P), ELISAh
16
(13)

PTP1B Antibody (B-9)

sc-133115mouse IgG2b κ301-435 (h)WB, IP, IF, ELISAh

new

(2)

PTP1B Antibody (H-9)

sc-133258mouse IgG1 κ301-435 (h)WB, IP, IF, IHC(P), ELISAh

new

(5)

PTP1B CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PTP1B CRISPR/Cas9 KO Plasmid (h)

sc-400732hGene KnockoutGFP0
(0)

PTP1B HDR Plasmid (h)

sc-400732-HDRhHomology Directed RepairPuromycin0
(0)

PTP1B Double Nickase Plasmid (h)

sc-400732-NIChGene KnockoutPuromycin0
(0)

PTP1B Double Nickase Plasmid (h2)

sc-400732-NIC-2hGene KnockoutPuromycin0
(0)

PTP1B CRISPR/Cas9 KO Plasmid (m)

sc-422502mGene KnockoutGFP0
(0)

PTP1B HDR Plasmid (m)

sc-422502-HDRmHomology Directed RepairPuromycin0
(0)

PTP1B Double Nickase Plasmid (m)

sc-422502-NICmGene KnockoutPuromycin0
(0)

PTP1B Double Nickase Plasmid (m2)

sc-422502-NIC-2mGene KnockoutPuromycin0
(0)

PTP1B CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PTP1B CRISPR Activation Plasmid (h)

sc-400732-ACThGene ActivationPuro, Blast, Hygro0
(0)

PTP1B CRISPR Activation Plasmid (h2)

sc-400732-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PTP1B Lentiviral Activation Particles (h)

sc-400732-LAChGene ActivationPuro, Blast, Hygro0
(0)

PTP1B Lentiviral Activation Particles (h2)

sc-400732-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PTP1B CRISPR Activation Plasmid (m)

sc-422502-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PTP1B CRISPR Activation Plasmid (m2)

sc-422502-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PTP1B Lentiviral Activation Particles (m)

sc-422502-LACmGene ActivationPuro, Blast, Hygro0
(0)

PTP1B Lentiviral Activation Particles (m2)

sc-422502-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PTP1B siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PTP1B siRNA (h)

sc-36328hGene SilencingN/A
5
(0)

PTP1B shRNA Plasmid (h)

sc-36328-SHhGene SilencingPuromycin
5
(0)

PTP1B shRNA (h) Lentiviral Particles

sc-36328-VhGene SilencingPuromycin
5
(0)

PTP1B siRNA (m)

sc-36329mGene SilencingN/A
3
(0)

PTP1B shRNA Plasmid (m)

sc-36329-SHmGene SilencingPuromycin
3
(0)

PTP1B shRNA (m) Lentiviral Particles

sc-36329-VmGene SilencingPuromycin
3
(0)

PTP1B siRNA (r)

sc-270525rGene SilencingN/A0
(0)

PTP1B shRNA Plasmid (r)

sc-270525-SHrGene SilencingPuromycin0
(0)

PTP1B shRNA (r) Lentiviral Particles

sc-270525-VrGene SilencingPuromycin0
(0)