Date published: 2026-7-9

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PTP1B Antibodies

Santa Cruz Biotechnology features a diverse variety of PTP1B monoclonal antibodies for research focused on understanding Protein Tyrosine Phosphatase 1B (PTP1B) in various biological processes. PTP1B monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PTP1B is a critical enzyme involved in the regulation of insulin signaling and plays a significant role in glucose homeostasis. Dysregulation of PTP1B has been implicated in metabolic disorders, including obesity and type 2 diabetes, making it a key target for therapeutic intervention. Research utilizing PTP1B monoclonal antibodies can provide valuable insights into the mechanisms underlying these conditions. PTP1B monoclonal antibodies enable researchers to investigate cellular signaling pathways with precision and reliability. Studying PTP1B expression patterns and interactions helps advance understanding of metabolic regulation and potential therapeutic strategies. Research conducted with Santa Cruz Biotechnology monoclonal antibodies contributes to advancing scientific knowledge in metabolic disease research and therapeutic development.

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PTP1B Antibodies

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PTP1B Antibody (D-4)

sc-133259mouse IgG1 κ301-435 (h)WB, IP, IF, IHC(P), ELISAh
16
(13)

PTP1B Antibody (B-9)

sc-133115mouse IgG2b κ301-435 (h)WB, IP, IF, ELISAh

new

(2)

PTP1B Antibody (H-9)

sc-133258mouse IgG1 κ301-435 (h)WB, IP, IF, IHC(P), ELISAh

new

(5)

PTP1B siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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PTP1B siRNA (h)

sc-36328hGene SilencingN/A
5
(0)

PTP1B shRNA Plasmid (h)

sc-36328-SHhGene SilencingPuromycin
5
(0)

PTP1B shRNA (h) Lentiviral Particles

sc-36328-VhGene SilencingPuromycin
5
(0)

PTP1B siRNA (m)

sc-36329mGene SilencingN/A
3
(0)

PTP1B shRNA Plasmid (m)

sc-36329-SHmGene SilencingPuromycin
3
(0)

PTP1B shRNA (m) Lentiviral Particles

sc-36329-VmGene SilencingPuromycin
3
(0)

PTP1B siRNA (r)

sc-270525rGene SilencingN/A0
(0)

PTP1B shRNA Plasmid (r)

sc-270525-SHrGene SilencingPuromycin0
(0)

PTP1B shRNA (r) Lentiviral Particles

sc-270525-VrGene SilencingPuromycin0
(0)

PTP1B CRISPR Knockout (KO) and HDR Plasmids

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PTP1B CRISPR/Cas9 KO Plasmid (h)

sc-400732Gene Knockouth0
(0)

PTP1B HDR Plasmid (h)

sc-400732-HDRHomology Directed Repairh0
(0)

PTP1B CRISPR/Cas9 KO Plasmid (m)

sc-422502Gene Knockoutm0
(0)

PTP1B HDR Plasmid (m)

sc-422502-HDRHomology Directed Repairm0
(0)

PTP1B CRISPR Double Nickase Plasmids

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PTP1B Double Nickase Plasmid (h)

sc-400732-NICGene Knockouth0
(0)

PTP1B Double Nickase Plasmid (h2)

sc-400732-NIC-2Gene Knockouth0
(0)

PTP1B Double Nickase Plasmid (m)

sc-422502-NICGene Knockoutm0
(0)

PTP1B CRISPR Activation Plasmids and Lentiviral Particles

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PTP1B CRISPR Activation Plasmid (h)

sc-400732-ACTGene Activationh0
(0)

PTP1B Lentiviral Activation Particles (h)

sc-400732-LACGene Activationh0
(0)