Date published: 2026-1-24

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Heterotrimeric G Protein CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. Heterotrimeric G Protein gene silencers are available as Heterotrimeric G Protein CRISPR/Cas9 Knockout plasmids and Heterotrimeric G Protein Double Nickase Plasmids. Heterotrimeric G Protein CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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Heterotrimeric G Protein CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Gα o CRISPR/Cas9 KO Plasmid (h)

sc-400897hGene KnockoutGFP0
(0)

Gα o Double Nickase Plasmid (h)

sc-400897-NIChGene KnockoutPuromycin0
(0)

Gα o Double Nickase Plasmid (h2)

sc-400897-NIC-2hGene KnockoutPuromycin0
(0)

Gα olf CRISPR/Cas9 KO Plasmid (h)

sc-401092hGene KnockoutGFP0
(0)

Gα olf HDR Plasmid (h)

sc-401092-HDRhHomology Directed RepairPuromycin0
(0)

Gα olf Double Nickase Plasmid (h)

sc-401092-NIChGene KnockoutPuromycin0
(0)

Gα olf Double Nickase Plasmid (h2)

sc-401092-NIC-2hGene KnockoutPuromycin0
(0)

Gα q CRISPR/Cas9 KO Plasmid (h)

sc-400500hGene KnockoutGFP0
(0)

Gα q HDR Plasmid (h)

sc-400500-HDRhHomology Directed RepairPuromycin0
(0)

Gα q Double Nickase Plasmid (h)

sc-400500-NIChGene KnockoutPuromycin0
(0)

Gα q Double Nickase Plasmid (h2)

sc-400500-NIC-2hGene KnockoutPuromycin0
(0)

Gα s/olf CRISPR/Cas9 KO Plasmid (m)

sc-420599mGene KnockoutGFP0
(0)

Gα s/olf HDR Plasmid (m)

sc-420599-HDRmHomology Directed RepairPuromycin0
(0)

Gα s CRISPR/Cas9 KO Plasmid (h)

sc-400476hGene KnockoutGFP0
(0)

Gα s HDR Plasmid (h)

sc-400476-HDRhHomology Directed RepairPuromycin0
(0)

Gα s Double Nickase Plasmid (h)

sc-400476-NIChGene KnockoutPuromycin0
(0)

Gα s Double Nickase Plasmid (h2)

sc-400476-NIC-2hGene KnockoutPuromycin0
(0)

Gα s CRISPR/Cas9 KO Plasmid (m)

sc-420602mGene KnockoutGFP0
(0)

Gα s HDR Plasmid (m)

sc-420602-HDRmHomology Directed RepairPuromycin0
(0)

Gα z Double Nickase Plasmid (h)

sc-402241-NIChGene KnockoutPuromycin0
(0)

Gα z Double Nickase Plasmid (h2)

sc-402241-NIC-2hGene KnockoutPuromycin0
(0)

GβL CRISPR/Cas9 KO Plasmid (m)

sc-425272mGene KnockoutGFP
1
(0)

Gα t1 Double Nickase Plasmid (h)

sc-401559-NIChGene KnockoutPuromycin0
(0)

Gα t1 Double Nickase Plasmid (h2)

sc-401559-NIC-2hGene KnockoutPuromycin0
(0)

Gα t1 CRISPR/Cas9 KO Plasmid (m)

sc-420603mGene KnockoutGFP0
(0)

Gα t1 HDR Plasmid (m)

sc-420603-HDRmHomology Directed RepairPuromycin0
(0)

Gβ 1 HDR Plasmid (h)

sc-401901-HDRhHomology Directed RepairPuromycin
1
(0)

Gβ 1 Double Nickase Plasmid (h)

sc-401901-NIChGene KnockoutPuromycin
1
(0)

Gβ 1 Double Nickase Plasmid (h2)

sc-401901-NIC-2hGene KnockoutPuromycin
1
(0)

Gα i-2 CRISPR/Cas9 KO Plasmid (h)

sc-400568hGene KnockoutGFP0
(0)

Gα i-2 Double Nickase Plasmid (h)

sc-400568-NIChGene KnockoutPuromycin0
(0)

Gα i-2 Double Nickase Plasmid (h2)

sc-400568-NIC-2hGene KnockoutPuromycin0
(0)

Gα t2 CRISPR/Cas9 KO Plasmid (h)

sc-401528hGene KnockoutGFP0
(0)

Gα t2 Double Nickase Plasmid (h)

sc-401528-NIChGene KnockoutPuromycin0
(0)

Gα t2 Double Nickase Plasmid (h2)

sc-401528-NIC-2hGene KnockoutPuromycin0
(0)

Gβ 2 CRISPR/Cas9 KO Plasmid (h)

sc-402936hGene KnockoutGFP0
(0)

Gβ 2 HDR Plasmid (h)

sc-402936-HDRhHomology Directed RepairPuromycin0
(0)

Gβ 2 Double Nickase Plasmid (h)

sc-402936-NIChGene KnockoutPuromycin0
(0)

Gβ 2 Double Nickase Plasmid (h2)

sc-402936-NIC-2hGene KnockoutPuromycin0
(0)

Gα i-3 CRISPR/Cas9 KO Plasmid (h)

sc-400453hGene KnockoutGFP0
(0)

Gα i-3 HDR Plasmid (h)

sc-400453-HDRhHomology Directed RepairPuromycin0
(0)

Gα i-3 Double Nickase Plasmid (h)

sc-400453-NIChGene KnockoutPuromycin0
(0)

Gα i-3 Double Nickase Plasmid (h2)

sc-400453-NIC-2hGene KnockoutPuromycin0
(0)

Gβ 3 Double Nickase Plasmid (h)

sc-404511-NIChGene KnockoutPuromycin0
(0)

Gβ 3 Double Nickase Plasmid (h2)

sc-404511-NIC-2hGene KnockoutPuromycin0
(0)

Gβ 4 CRISPR/Cas9 KO Plasmid (h)

sc-400820hGene KnockoutGFP0
(0)

Gβ 4 HDR Plasmid (h)

sc-400820-HDRhHomology Directed RepairPuromycin0
(0)

Gγ 5 HDR Plasmid (h2)

sc-407524-HDR-2hHomology Directed RepairPuromycin0
(0)

Gβ 5 CRISPR/Cas9 KO Plasmid (h)

sc-403365hGene KnockoutGFP0
(0)

Gβ 5 HDR Plasmid (h)

sc-403365-HDRhHomology Directed RepairPuromycin0
(0)

Gβ 5 CRISPR/Cas9 KO Plasmid (m)

sc-420611mGene KnockoutGFP
1
(0)

Gγ 5 CRISPR/Cas9 KO Plasmid (h)

sc-407524hGene KnockoutGFP0
(0)

Gα 11 CRISPR/Cas9 KO Plasmid (h2)

sc-401653-KO-2hGene KnockoutGFP0
(0)

Gα 11 Double Nickase Plasmid (h)

sc-401653-NIChGene KnockoutPuromycin0
(0)

Gα 11 Double Nickase Plasmid (h2)

sc-401653-NIC-2hGene KnockoutPuromycin0
(0)

Gγ 11 CRISPR/Cas9 KO Plasmid (h)

sc-410797hGene KnockoutGFP0
(0)

Gγ 11 HDR Plasmid (h)

sc-410797-HDRhHomology Directed RepairPuromycin0
(0)

Gα i-1/GNAI1 CRISPR/Cas9 KO Plasmid (h2)

sc-400652-KO-2hGene KnockoutGFP0
(0)

Gα i-1/GNAI1 HDR Plasmid (h2)

sc-400652-HDR-2hHomology Directed RepairPuromycin0
(0)

Gα i-1/GNAI1 Double Nickase Plasmid (h)

sc-400652-NIChGene KnockoutPuromycin0
(0)

Gα i-1/GNAI1 Double Nickase Plasmid (h2)

sc-400652-NIC-2hGene KnockoutPuromycin0
(0)

Gα 12 CRISPR/Cas9 KO Plasmid (h)

sc-401264hGene KnockoutGFP0
(0)

Gα 12 HDR Plasmid (h)

sc-401264-HDRhHomology Directed RepairPuromycin0
(0)

Gα 12 Double Nickase Plasmid (h)

sc-401264-NIChGene KnockoutPuromycin0
(0)

Gα 12 Double Nickase Plasmid (h2)

sc-401264-NIC-2hGene KnockoutPuromycin0
(0)

Gα 13 CRISPR/Cas9 KO Plasmid (h)

sc-401180hGene KnockoutGFP0
(0)

Gα 13 HDR Plasmid (h)

sc-401180-HDRhHomology Directed RepairPuromycin0
(0)

Gα 13 Double Nickase Plasmid (h)

sc-401180-NIChGene KnockoutPuromycin0
(0)

Gα 13 Double Nickase Plasmid (h2)

sc-401180-NIC-2hGene KnockoutPuromycin0
(0)

Gα 14 CRISPR/Cas9 KO Plasmid (h)

sc-404556hGene KnockoutGFP0
(0)

Gα 14 HDR Plasmid (h)

sc-404556-HDRhHomology Directed RepairPuromycin0
(0)

Gα 14 Double Nickase Plasmid (h)

sc-404556-NIChGene KnockoutPuromycin0
(0)

Gα 14 Double Nickase Plasmid (h2)

sc-404556-NIC-2hGene KnockoutPuromycin0
(0)

Gα 15 CRISPR/Cas9 KO Plasmid (h2)

sc-403266-KO-2hGene KnockoutGFP0
(0)

Gα 15 Double Nickase Plasmid (h)

sc-403266-NIChGene KnockoutPuromycin0
(0)

Gα 15 Double Nickase Plasmid (h2)

sc-403266-NIC-2hGene KnockoutPuromycin0
(0)

Heterotrimeric G Protein CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Gα o CRISPR Activation Plasmid (h)

sc-400897-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gα q CRISPR Activation Plasmid (h)

sc-400500-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gα q Lentiviral Activation Particles (h)

sc-400500-LAChGene ActivationPuro, Blast, Hygro0
(0)

Gα q CRISPR Activation Plasmid (m)

sc-420601-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Gα q CRISPR Activation Plasmid (m2)

sc-420601-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Gα s CRISPR Activation Plasmid (h)

sc-400476-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gα s CRISPR Activation Plasmid (h2)

sc-400476-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Gα z CRISPR Activation Plasmid (h)

sc-402241-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gα z CRISPR Activation Plasmid (h2)

sc-402241-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Gα t1 CRISPR Activation Plasmid (h)

sc-401559-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gβ 1 CRISPR Activation Plasmid (h)

sc-401901-ACThGene ActivationPuro, Blast, Hygro
1
(0)

Gβ 1 CRISPR Activation Plasmid (h2)

sc-401901-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

Gβ 1 Lentiviral Activation Particles (h2)

sc-401901-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

Gβ 1 CRISPR Activation Plasmid (m)

sc-420606-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Gβ 1 CRISPR Activation Plasmid (m2)

sc-420606-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Gβ 1 Lentiviral Activation Particles (m2)

sc-420606-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Gα i-2 CRISPR Activation Plasmid (h)

sc-400568-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gα i-2 CRISPR Activation Plasmid (h2)

sc-400568-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Gα t2 CRISPR Activation Plasmid (h)

sc-401528-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gβ 2 CRISPR Activation Plasmid (h)

sc-402936-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gβ 2 CRISPR Activation Plasmid (h2)

sc-402936-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Gα i-3 CRISPR Activation Plasmid (h)

sc-400453-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gβ 4 CRISPR Activation Plasmid (h)

sc-400820-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gγ 10 CRISPR Activation Plasmid (m)

sc-420613-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Gγ 10 CRISPR Activation Plasmid (m2)

sc-420613-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Gγ 10 Lentiviral Activation Particles (m2)

sc-420613-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Gα 11 CRISPR Activation Plasmid (h)

sc-401653-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gα 11 CRISPR Activation Plasmid (h2)

sc-401653-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Gα 12 CRISPR Activation Plasmid (h)

sc-401264-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gα 13 CRISPR Activation Plasmid (h)

sc-401180-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gγ13 CRISPR Activation Plasmid (h)

sc-403045-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gγ13 CRISPR Activation Plasmid (h2)

sc-403045-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Gα 14 CRISPR Activation Plasmid (h)

sc-404556-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gα 15 CRISPR Activation Plasmid (h)

sc-403266-ACThGene ActivationPuro, Blast, Hygro0
(0)