UGT Antibodies

Santa Cruz Biotechnology features a diverse variety of UGT monoclonal antibodies for studying UDP-glucuronosyltransferases (UGTs), a family of enzymes crucial for the metabolism of various endogenous and exogenous compounds. UGT monoclonal antibodies support multiple research applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). UDP-glucuronosyltransferases play a vital role in the detoxification process by facilitating the conjugation of glucuronic acid to a wide range of substrates, including drugs, hormones, and bilirubin. This process enhances the solubility of compounds, promoting their excretion from the body and thereby maintaining homeostasis. Understanding the function and regulation of UDP-glucuronosyltransferases is essential for elucidating drug metabolism and the pharmacokinetics of therapeutic agents. Research into UDP-glucuronosyltransferases continues to reveal new insights about their role in drug processing and cellular detoxification. Investigating UDP-glucuronosyltransferase activity helps advance our knowledge of metabolic pathways and therapeutic responses. Santa Cruz Biotechnology monoclonal antibodies for UGT research support scientists worldwide in advancing our understanding of drug metabolism and therapeutic development.