Date published: 2026-7-10

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HDAC CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. HDAC gene silencers are available as HDAC CRISPR/Cas9 Knockout plasmids and HDAC Double Nickase Plasmids. HDAC CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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HDAC CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Histone Deacetylase 1 (HDAC1) CRISPR/Cas9 KO Plasmid (h)

sc-400203Gene Knockouth0
(0)

Histone Deacetylase 4 (HDAC4) CRISPR/Cas9 KO Plasmid (h)

sc-400388Gene Knockouth0
(0)

Histone Deacetylase 5 (HDAC5) CRISPR/Cas9 KO Plasmid (h)

sc-400659Gene Knockouth0
(0)

Histone Deacetylase 8 (HDAC8) CRISPR/Cas9 KO Plasmid (h)

sc-400757Gene Knockouth0
(0)

Histone Deacetylase 7 (HDAC7) CRISPR/Cas9 KO Plasmid (h)

sc-400989Gene Knockouth0
(0)

Histone Deacetylase 9 (HDAC9) CRISPR/Cas9 KO Plasmid (h)

sc-401419Gene Knockouth0
(0)

Histone Deacetylase 11 (HDAC11) CRISPR/Cas9 KO Plasmid (h)

sc-402103Gene Knockouth0
(0)

Histone Deacetylase 6 (HDAC6) CRISPR/Cas9 KO Plasmid (m)

sc-420820Gene Knockoutm0
(0)

Histone Deacetylase 9 (HDAC9) CRISPR/Cas9 KO Plasmid (m)

sc-429766Gene Knockoutm0
(0)

Histone Deacetylase 11 (HDAC11) CRISPR/Cas9 KO Plasmid (m)

sc-433149Gene Knockoutm0
(0)

Histone Deacetylase 1 (HDAC1) CRISPR/Cas9 KO Plasmid (m)

sc-436647Gene Knockoutm0
(0)

Histone Deacetylase 1 (HDAC1) CRISPR/Cas9 KO Plasmid (r)

sc-437285Gene Knockoutr0
(0)

Histone Deacetylase 2 (HDAC2) CRISPR/Cas9 KO Plasmid (r)

sc-437286Gene Knockoutr0
(0)

Histone Deacetylase 1 (HDAC1) HDR Plasmid (h)

sc-400203-HDRHomology Directed Repairh0
(0)

Histone Deacetylase 4 (HDAC4) HDR Plasmid (h)

sc-400388-HDRHomology Directed Repairh0
(0)

Histone Deacetylase 5 (HDAC5) HDR Plasmid (h)

sc-400659-HDRHomology Directed Repairh0
(0)

Histone Deacetylase 8 (HDAC8) HDR Plasmid (h)

sc-400757-HDRHomology Directed Repairh0
(0)

Histone Deacetylase 7 (HDAC7) HDR Plasmid (h)

sc-400989-HDRHomology Directed Repairh0
(0)

Histone Deacetylase 9 (HDAC9) HDR Plasmid (h)

sc-401419-HDRHomology Directed Repairh0
(0)

Histone Deacetylase 11 (HDAC11) HDR Plasmid (h)

sc-402103-HDRHomology Directed Repairh0
(0)

Histone Deacetylase 6 (HDAC6) HDR Plasmid (m)

sc-420820-HDRHomology Directed Repairm0
(0)

Histone Deacetylase 9 (HDAC9) HDR Plasmid (m)

sc-429766-HDRHomology Directed Repairm0
(0)

Histone Deacetylase 11 (HDAC11) HDR Plasmid (m)

sc-433149-HDRHomology Directed Repairm0
(0)

Histone Deacetylase 1 (HDAC1) HDR Plasmid (m)

sc-436647-HDRHomology Directed Repairm0
(0)

Histone Deacetylase 2 (HDAC2) CRISPR/Cas9 KO Plasmid (h2)

sc-400303-KO-2Gene Knockouth0
(0)

Histone Deacetylase 6 (HDAC6) CRISPR/Cas9 KO Plasmid (h2)

sc-400314-KO-2Gene Knockouth0
(0)

Histone Deacetylase 3 (HDAC3) CRISPR/Cas9 KO Plasmid (h2)

sc-400446-KO-2Gene Knockouth0
(0)

Histone Deacetylase 10 (HDAC10) CRISPR/Cas9 KO Plasmid (h2)

sc-403221-KO-2Gene Knockouth0
(0)

Histone Deacetylase 2 (HDAC2) CRISPR/Cas9 KO Plasmid (m2)

sc-420817-KO-2Gene Knockoutm0
(0)

Histone Deacetylase 3 (HDAC3) CRISPR/Cas9 KO Plasmid (m2)

sc-420818-KO-2Gene Knockoutm0
(0)

Histone Deacetylase 2 (HDAC2) HDR Plasmid (h2)

sc-400303-HDR-2Homology Directed Repairh0
(0)

Histone Deacetylase 6 (HDAC6) HDR Plasmid (h2)

sc-400314-HDR-2Homology Directed Repairh0
(0)

Histone Deacetylase 3 (HDAC3) HDR Plasmid (h2)

sc-400446-HDR-2Homology Directed Repairh0
(0)

Histone Deacetylase 10 (HDAC10) HDR Plasmid (h2)

sc-403221-HDR-2Homology Directed Repairh0
(0)

Histone Deacetylase 2 (HDAC2) HDR Plasmid (m2)

sc-420817-HDR-2Homology Directed Repairm0
(0)

Histone Deacetylase 3 (HDAC3) HDR Plasmid (m2)

sc-420818-HDR-2Homology Directed Repairm0
(0)

HDAC CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Histone Deacetylase 1 (HDAC1) Double Nickase Plasmid (h)

sc-400203-NICGene Knockouth0
(0)

Histone Deacetylase 2 (HDAC2) Double Nickase Plasmid (h)

sc-400303-NICGene Knockouth0
(0)

Histone Deacetylase 6 (HDAC6) Double Nickase Plasmid (h)

sc-400314-NICGene Knockouth0
(0)

Histone Deacetylase 4 (HDAC4) Double Nickase Plasmid (h)

sc-400388-NICGene Knockouth0
(0)

Histone Deacetylase 3 (HDAC3) Double Nickase Plasmid (h)

sc-400446-NICGene Knockouth0
(0)

Histone Deacetylase 5 (HDAC5) Double Nickase Plasmid (h)

sc-400659-NICGene Knockouth0
(0)

Histone Deacetylase 8 (HDAC8) Double Nickase Plasmid (h)

sc-400757-NICGene Knockouth0
(0)

Histone Deacetylase 7 (HDAC7) Double Nickase Plasmid (h)

sc-400989-NICGene Knockouth0
(0)

Histone Deacetylase 9 (HDAC9) Double Nickase Plasmid (h)

sc-401419-NICGene Knockouth0
(0)

Histone Deacetylase 11 (HDAC11) Double Nickase Plasmid (h)

sc-402103-NICGene Knockouth0
(0)

Histone Deacetylase 10 (HDAC10) Double Nickase Plasmid (h)

sc-403221-NICGene Knockouth0
(0)

Histone Deacetylase 3 (HDAC3) Double Nickase Plasmid (m)

sc-420818-NICGene Knockoutm0
(0)

Histone Deacetylase 5 (HDAC5) Double Nickase Plasmid (m)

sc-420819-NICGene Knockoutm0
(0)

Histone Deacetylase 6 (HDAC6) Double Nickase Plasmid (m)

sc-420820-NICGene Knockoutm0
(0)

Histone Deacetylase 4 (HDAC4) Double Nickase Plasmid (m)

sc-431586-NICGene Knockoutm0
(0)

Histone Deacetylase 1 (HDAC1) Double Nickase Plasmid (m)

sc-436647-NICGene Knockoutm0
(0)

Histone Deacetylase 1 (HDAC1) Double Nickase Plasmid (h2)

sc-400203-NIC-2Gene Knockouth0
(0)

Histone Deacetylase 2 (HDAC2) Double Nickase Plasmid (h2)

sc-400303-NIC-2Gene Knockouth0
(0)

Histone Deacetylase 6 (HDAC6) Double Nickase Plasmid (h2)

sc-400314-NIC-2Gene Knockouth0
(0)

Histone Deacetylase 4 (HDAC4) Double Nickase Plasmid (h2)

sc-400388-NIC-2Gene Knockouth0
(0)

Histone Deacetylase 3 (HDAC3) Double Nickase Plasmid (h2)

sc-400446-NIC-2Gene Knockouth0
(0)

Histone Deacetylase 5 (HDAC5) Double Nickase Plasmid (h2)

sc-400659-NIC-2Gene Knockouth0
(0)

Histone Deacetylase 8 (HDAC8) Double Nickase Plasmid (h2)

sc-400757-NIC-2Gene Knockouth0
(0)

Histone Deacetylase 7 (HDAC7) Double Nickase Plasmid (h2)

sc-400989-NIC-2Gene Knockouth0
(0)

Histone Deacetylase 9 (HDAC9) Double Nickase Plasmid (h2)

sc-401419-NIC-2Gene Knockouth0
(0)

Histone Deacetylase 11 (HDAC11) Double Nickase Plasmid (h2)

sc-402103-NIC-2Gene Knockouth0
(0)

Histone Deacetylase 10 (HDAC10) Double Nickase Plasmid (h2)

sc-403221-NIC-2Gene Knockouth0
(0)

Histone Deacetylase 3 (HDAC3) Double Nickase Plasmid (m2)

sc-420818-NIC-2Gene Knockoutm0
(0)

Histone Deacetylase 5 (HDAC5) Double Nickase Plasmid (m2)

sc-420819-NIC-2Gene Knockoutm0
(0)

Histone Deacetylase 6 (HDAC6) Double Nickase Plasmid (m2)

sc-420820-NIC-2Gene Knockoutm0
(0)

Histone Deacetylase 1 (HDAC1) Double Nickase Plasmid (m2)

sc-436647-NIC-2Gene Knockoutm0
(0)

HDAC CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Histone Deacetylase 1 (HDAC1) CRISPR Activation Plasmid (h)

sc-400203-ACTGene Activationh0
(0)

Histone Deacetylase 2 (HDAC2) CRISPR Activation Plasmid (h)

sc-400303-ACTGene Activationh0
(0)

Histone Deacetylase 6 (HDAC6) CRISPR Activation Plasmid (h)

sc-400314-ACTGene Activationh0
(0)

Histone Deacetylase 4 (HDAC4) CRISPR Activation Plasmid (h)

sc-400388-ACTGene Activationh0
(0)

Histone Deacetylase 3 (HDAC3) CRISPR Activation Plasmid (h)

sc-400446-ACTGene Activationh0
(0)

Histone Deacetylase 5 (HDAC5) CRISPR Activation Plasmid (h)

sc-400659-ACTGene Activationh0
(0)

Histone Deacetylase 8 (HDAC8) CRISPR Activation Plasmid (h)

sc-400757-ACTGene Activationh0
(0)

Histone Deacetylase 7 (HDAC7) CRISPR Activation Plasmid (h)

sc-400989-ACTGene Activationh0
(0)

Histone Deacetylase 9 (HDAC9) CRISPR Activation Plasmid (h)

sc-401419-ACTGene Activationh0
(0)

Histone Deacetylase 11 (HDAC11) CRISPR Activation Plasmid (h)

sc-402103-ACTGene Activationh0
(0)

Histone Deacetylase 10 (HDAC10) CRISPR Activation Plasmid (h)

sc-403221-ACTGene Activationh0
(0)

Histone Deacetylase 6 (HDAC6) CRISPR Activation Plasmid (m)

sc-420820-ACTGene Activationm0
(0)

Histone Deacetylase 9 (HDAC9) CRISPR Activation Plasmid (m)

sc-429766-ACTGene Activationm0
(0)

Histone Deacetylase 1 (HDAC1) CRISPR Activation Plasmid (m)

sc-436647-ACTGene Activationm0
(0)

Histone Deacetylase 2 (HDAC2) CRISPR Activation Plasmid (h2)

sc-400303-ACT-2Gene Activationh0
(0)

Histone Deacetylase 6 (HDAC6) CRISPR Activation Plasmid (h2)

sc-400314-ACT-2Gene Activationh0
(0)

Histone Deacetylase 3 (HDAC3) CRISPR Activation Plasmid (h2)

sc-400446-ACT-2Gene Activationh0
(0)

Histone Deacetylase 9 (HDAC9) CRISPR Activation Plasmid (h2)

sc-401419-ACT-2Gene Activationh0
(0)

Histone Deacetylase 11 (HDAC11) CRISPR Activation Plasmid (h2)

sc-402103-ACT-2Gene Activationh0
(0)

Histone Deacetylase 10 (HDAC10) CRISPR Activation Plasmid (h2)

sc-403221-ACT-2Gene Activationh0
(0)

Histone Deacetylase 6 (HDAC6) CRISPR Activation Plasmid (m2)

sc-420820-ACT-2Gene Activationm0
(0)

Histone Deacetylase 9 (HDAC9) CRISPR Activation Plasmid (m2)

sc-429766-ACT-2Gene Activationm0
(0)

Histone Deacetylase 1 (HDAC1) CRISPR Activation Plasmid (m2)

sc-436647-ACT-2Gene Activationm0
(0)

Histone Deacetylase 11 (HDAC11) Lentiviral Activation Particles (h)

sc-402103-LACGene Activationh0
(0)

Histone Deacetylase 6 (HDAC6) Lentiviral Activation Particles (m)

sc-420820-LACGene Activationm0
(0)

Histone Deacetylase 1 (HDAC1) Lentiviral Activation Particles (m)

sc-436647-LACGene Activationm0
(0)

Histone Deacetylase 11 (HDAC11) Lentiviral Activation Particles (h2)

sc-402103-LAC-2Gene Activationh0
(0)

Histone Deacetylase 1 (HDAC1) Lentiviral Activation Particles (m2)

sc-436647-LAC-2Gene Activationm0
(0)