Date published: 2025-10-18

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HDAC Activators

Santa Cruz Biotechnology now offers a broad range of HDAC Activators for use in various applications. HDAC activators are compounds that enhance the activity of histone deacetylases (HDACs), a class of enzymes that play a crucial role in the regulation of gene expression by removing acetyl groups from histone proteins. This removal leads to a more compact chromatin structure and generally results in the repression of gene transcription. In scientific research, HDAC activators are instrumental in studies exploring epigenetic mechanisms, as they provide a tool for modulating chromatin structure and gene expression. They are valuable in explaining the role of HDACs in cellular processes such as differentiation, apoptosis, and cell cycle regulation. The ability to activate HDACs allows researchers to investigate the complex interplay between chromatin remodeling and various biological pathways, making HDAC activators a vital asset in the study of gene regulation, developmental biology, and cancer research. These compounds are also used in high-throughput screening assays to identify new modulators of HDAC activity, contributing to the advancement of our understanding of epigenetic regulation. View detailed information on our available HDAC Activators by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

ITSA1

200626-61-5sc-200894B
sc-200894
sc-200894A
10 mg
25 mg
100 mg
$66.00
$107.00
$311.00
4
(1)

ITSA1 functions as a histone deacetylase (HDAC) inhibitor, characterized by its ability to disrupt the zinc-binding site of HDAC enzymes. This compound exhibits a unique binding affinity, promoting conformational changes that alter enzyme activity. Its kinetic behavior showcases a rapid onset of inhibition, significantly affecting histone acetylation levels. Furthermore, ITSA1's selective interaction with specific HDAC isoforms influences gene expression regulation, impacting cellular signaling pathways.