Date published: 2026-7-12

1-800-457-3801

SCBT Portrait Logo
Seach Input

SOCS Antibodies

Santa Cruz Biotechnology features a diverse variety of SOCS monoclonal antibodies for studying Suppressor of Cytokine Signaling (SOCS) proteins. SOCS monoclonal antibodies are compatible with multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SOCS proteins function as negative feedback regulators in cytokine signaling pathways, helping maintain cellular homeostasis. Their significance extends to various physiological processes, including immune response, cell growth, and differentiation. Dysregulation of SOCS proteins has been linked to numerous diseases, including cancer and autoimmune disorders, making them an important research focus. Understanding SOCS protein function and regulation continues to reveal new insights into cellular signaling mechanisms. Ongoing research explores how SOCS proteins influence different cellular pathways and their potential as therapeutic targets. SOCS monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance scientific understanding of cellular regulation and disease mechanisms.

SEE ALSO...

SOCS Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SOCS-1 Antibody (E-9)

sc-518028mouse IgG2a κ184-211 (h)WB, IP, IF, ELISAm, r, h
14
(4)

SOCS-3 Antibody (6A463)

sc-73045mouse IgG2b κFL (h)WB, IP, ELISAm, r, h
20
(17)

SOCS-3 Antibody (SO1)

sc-51699mouse IgG2bFL (h)WB, IP, ELISAm, r, h
18
(9)

SOCS-3 Antibody (G-5)

sc-518020mouse IgG1 κ200-225 (m)WB, IP, IF, IHC(P), ELISAm, r, h
8
(1)

SOCS-4 Antibody (F-1)

sc-518223mouse IgG1 κ233-258 (h)WB, IP, IF, ELISAh

new

(1)

SOCS-4 Antibody (9J12)

sc-135566mouse IgG2b κ1-441 (h)WB, IP, ELISAh
1
(2)

SOCS-5 Antibody (31-L)

sc-100858mouse IgG1 κ1-110 (h)WB, IP, IF, IHC(P), ELISAm, r, h
7
(2)

SOCS-6 Antibody (G-3)

sc-74597mouse IgG1 κ132-382 (h)WB, IP, IF, ELISAm, r, h

new

(3)

SOCS-6 Antibody (B-11)

sc-133058mouse IgG1 κ132-382 (h)WB, IP, IF, ELISAh
3
(1)

SOCS-7 Antibody (E-8)

sc-137241mouse IgG1 κ73-184 (h)WB, IP, IF, ELISAm, r, h
2
(1)

SOCS siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SOCS-1 siRNA (h)

sc-40996hGene SilencingN/A
13
(0)

SOCS-1 shRNA Plasmid (h)

sc-40996-SHhGene SilencingPuromycin
13
(0)

SOCS-1 shRNA (h) Lentiviral Particles

sc-40996-VhGene SilencingPuromycin
13
(0)

SOCS-1 siRNA (m)

sc-40997mGene SilencingN/A
18
(0)

SOCS-1 shRNA Plasmid (m)

sc-40997-SHmGene SilencingPuromycin
18
(0)

SOCS-1 shRNA (m) Lentiviral Particles

sc-40997-VmGene SilencingPuromycin
18
(0)

SOCS-2 siRNA (h)

sc-40998hGene SilencingN/A
3
(0)

SOCS-2 shRNA Plasmid (h)

sc-40998-SHhGene SilencingPuromycin
3
(0)

SOCS-2 shRNA (h) Lentiviral Particles

sc-40998-VhGene SilencingPuromycin
3
(0)

SOCS-2 siRNA (m)

sc-40999mGene SilencingN/A0
(0)

SOCS-2 shRNA Plasmid (m)

sc-40999-SHmGene SilencingPuromycin0
(0)

SOCS-2 shRNA (m) Lentiviral Particles

sc-40999-VmGene SilencingPuromycin0
(0)

SOCS-3 siRNA (h)

sc-41000hGene SilencingN/A
14
(0)

SOCS-3 shRNA Plasmid (h)

sc-41000-SHhGene SilencingPuromycin
14
(0)

SOCS-3 shRNA (h) Lentiviral Particles

sc-41000-VhGene SilencingPuromycin
14
(0)

SOCS-3 siRNA (m)

sc-41001mGene SilencingN/A
20
(0)

SOCS-3 shRNA Plasmid (m)

sc-41001-SHmGene SilencingPuromycin
20
(0)

SOCS-3 shRNA (m) Lentiviral Particles

sc-41001-VmGene SilencingPuromycin
20
(0)

SOCS-3 siRNA (r)

sc-270156rGene SilencingN/A
1
(0)

SOCS-3 shRNA Plasmid (r)

sc-270156-SHrGene SilencingPuromycin
1
(0)

SOCS-3 shRNA (r) Lentiviral Particles

sc-270156-VrGene SilencingPuromycin
1
(0)

SOCS-4 siRNA (h)

sc-63050hGene SilencingN/A
1
(0)

SOCS-4 shRNA Plasmid (h)

sc-63050-SHhGene SilencingPuromycin
1
(0)

SOCS-4 shRNA (h) Lentiviral Particles

sc-63050-VhGene SilencingPuromycin
1
(0)

SOCS-4 siRNA (m)

sc-63051mGene SilencingN/A0
(0)

SOCS-4 shRNA Plasmid (m)

sc-63051-SHmGene SilencingPuromycin0
(0)

SOCS-4 shRNA (m) Lentiviral Particles

sc-63051-VmGene SilencingPuromycin0
(0)

SOCS-5 siRNA (h)

sc-41002hGene SilencingN/A
2
(0)

SOCS-5 shRNA Plasmid (h)

sc-41002-SHhGene SilencingPuromycin
2
(0)

SOCS-5 shRNA (h) Lentiviral Particles

sc-41002-VhGene SilencingPuromycin
2
(0)

SOCS-5 siRNA (m)

sc-41003mGene SilencingN/A0
(0)

SOCS-5 shRNA Plasmid (m)

sc-41003-SHmGene SilencingPuromycin0
(0)

SOCS-5 shRNA (m) Lentiviral Particles

sc-41003-VmGene SilencingPuromycin0
(0)

SOCS-6 siRNA (h)

sc-36520hGene SilencingN/A0
(0)

SOCS-6 shRNA Plasmid (h)

sc-36520-SHhGene SilencingPuromycin0
(0)

SOCS-6 shRNA (h) Lentiviral Particles

sc-36520-VhGene SilencingPuromycin0
(0)

SOCS-6 siRNA (m)

sc-36521mGene SilencingN/A0
(0)

SOCS-6 shRNA Plasmid (m)

sc-36521-SHmGene SilencingPuromycin0
(0)

SOCS-6 shRNA (m) Lentiviral Particles

sc-36521-VmGene SilencingPuromycin0
(0)

SOCS-7 siRNA (h)

sc-41004hGene SilencingN/A
1
(0)

SOCS-7 shRNA Plasmid (h)

sc-41004-SHhGene SilencingPuromycin
1
(0)

SOCS-7 shRNA (h) Lentiviral Particles

sc-41004-VhGene SilencingPuromycin
1
(0)

SOCS-7 siRNA (m)

sc-41005mGene SilencingN/A0
(0)

SOCS-7 shRNA Plasmid (m)

sc-41005-SHmGene SilencingPuromycin0
(0)

SOCS-7 shRNA (m) Lentiviral Particles

sc-41005-VmGene SilencingPuromycin0
(0)

SOCS CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

SOCS-1 CRISPR/Cas9 KO Plasmid (h2)

sc-400618-KO-2Gene Knockouth0
(0)

SOCS-1 HDR Plasmid (h2)

sc-400618-HDR-2Homology Directed Repairh0
(0)

SOCS-1 CRISPR/Cas9 KO Plasmid (m)

sc-419667Gene Knockoutm0
(0)

SOCS-1 HDR Plasmid (m)

sc-419667-HDRHomology Directed Repairm0
(0)

SOCS-2 CRISPR/Cas9 KO Plasmid (h)

sc-402034Gene Knockouth0
(0)

SOCS-2 HDR Plasmid (h)

sc-402034-HDRHomology Directed Repairh0
(0)

SOCS-2 CRISPR/Cas9 KO Plasmid (m)

sc-432073Gene Knockoutm0
(0)

SOCS-2 HDR Plasmid (m)

sc-432073-HDRHomology Directed Repairm0
(0)

SOCS-3 CRISPR/Cas9 KO Plasmid (h2)

sc-400455-KO-2Gene Knockouth0
(0)

SOCS-3 HDR Plasmid (h2)

sc-400455-HDR-2Homology Directed Repairh0
(0)

SOCS-3 CRISPR/Cas9 KO Plasmid (m2)

sc-419666-KO-2Gene Knockoutm0
(0)

SOCS-3 HDR Plasmid (m2)

sc-419666-HDR-2Homology Directed Repairm0
(0)

SOCS-4 CRISPR/Cas9 KO Plasmid (h)

sc-406094Gene Knockouth0
(0)

SOCS-4 HDR Plasmid (h)

sc-406094-HDRHomology Directed Repairh0
(0)

SOCS-5 CRISPR/Cas9 KO Plasmid (h)

sc-402585Gene Knockouth0
(0)

SOCS-6 CRISPR/Cas9 KO Plasmid (h)

sc-402344Gene Knockouth0
(0)

SOCS CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

SOCS-1 Double Nickase Plasmid (m)

sc-419667-NICGene Knockoutm0
(0)

SOCS-3 Double Nickase Plasmid (m)

sc-419666-NICGene Knockoutm0
(0)

SOCS CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

SOCS-1 CRISPR Activation Plasmid (h)

sc-400618-ACTGene Activationh0
(0)

SOCS-1 CRISPR Activation Plasmid (h2)

sc-400618-ACT-2Gene Activationh0
(0)

SOCS-3 CRISPR Activation Plasmid (h)

sc-400455-ACTGene Activationh0
(0)

SOCS-3 CRISPR Activation Plasmid (m2)

sc-419666-ACT-2Gene Activationm0
(0)

SOCS-6 CRISPR Activation Plasmid (h)

sc-402344-ACTGene Activationh0
(0)