Date published: 2025-11-21

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SOCS-3 Antibodies

Santa Cruz Biotechnology delivers a wide array of SOCS-3 monoclonal antibodies for research focused on understanding Suppressor of Cytokine Signaling 3 (SOCS-3) in various biological processes. SOCS-3 Antibodies for SOCS-3 are validated for multiple applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SOCS-3 is a critical regulator of cytokine signaling, playing a vital role in modulating immune responses and inflammation. SOCS-3 functions in the negative feedback regulation of cytokine signaling pathways, which is essential for maintaining cellular homeostasis. Dysregulation of SOCS-3 has been implicated in various diseases, including cancer and autoimmune disorders, making it an important target for therapeutic intervention. SOCS-3 research continues to reveal new insights into cellular signaling mechanisms and disease pathways. Understanding SOCS-3 function and regulation holds significant potential for developing new therapeutic strategies. SOCS-3 monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance scientific understanding of cellular signaling and disease mechanisms.

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SOCS-3 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SOCS-3 Antibody (6A463)

sc-73045mouse IgG2b κFL (h)WB, IP, ELISAm, r, h
20
(16)

SOCS-3 Antibody (SO1)

sc-51699mouse IgG2bFL (h)WB, IP, ELISAm, r, h
18
(9)

SOCS-3 Antibody (G-5)

sc-518020mouse IgG1 κ200-225 (m)WB, IP, IF, IHC(P), ELISAm, r, h
8
(1)

SOCS-3 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SOCS-3 CRISPR/Cas9 KO Plasmid (h2)

sc-400455-KO-2hGene KnockoutGFP
1
(0)

SOCS-3 HDR Plasmid (h2)

sc-400455-HDR-2hHomology Directed RepairPuromycin
1
(0)

SOCS-3 Double Nickase Plasmid (h)

sc-400455-NIChGene KnockoutPuromycin
1
(0)

SOCS-3 Double Nickase Plasmid (h2)

sc-400455-NIC-2hGene KnockoutPuromycin
1
(0)

SOCS-3 CRISPR/Cas9 KO Plasmid (m2)

sc-419666-KO-2mGene KnockoutGFP
1
(0)

SOCS-3 HDR Plasmid (m2)

sc-419666-HDR-2mHomology Directed RepairPuromycin
1
(0)

SOCS-3 Double Nickase Plasmid (m)

sc-419666-NICmGene KnockoutPuromycin
1
(0)

SOCS-3 Double Nickase Plasmid (m2)

sc-419666-NIC-2mGene KnockoutPuromycin
1
(0)

SOCS-3 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SOCS-3 CRISPR Activation Plasmid (h)

sc-400455-ACThGene ActivationPuro, Blast, Hygro
1
(0)

SOCS-3 CRISPR Activation Plasmid (h2)

sc-400455-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

SOCS-3 Lentiviral Activation Particles (h)

sc-400455-LAChGene ActivationPuro, Blast, Hygro
1
(0)

SOCS-3 Lentiviral Activation Particles (h2)

sc-400455-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

SOCS-3 CRISPR Activation Plasmid (m)

sc-419666-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

SOCS-3 CRISPR Activation Plasmid (m2)

sc-419666-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

SOCS-3 Lentiviral Activation Particles (m)

sc-419666-LACmGene ActivationPuro, Blast, Hygro
1
(0)

SOCS-3 Lentiviral Activation Particles (m2)

sc-419666-LAC-2mGene ActivationPuro, Blast, Hygro
1
(0)

SOCS-3 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SOCS-3 siRNA (h)

sc-41000hGene SilencingN/A
14
(0)

SOCS-3 shRNA Plasmid (h)

sc-41000-SHhGene SilencingPuromycin
14
(0)

SOCS-3 shRNA (h) Lentiviral Particles

sc-41000-VhGene SilencingPuromycin
14
(0)

SOCS-3 siRNA (m)

sc-41001mGene SilencingN/A
20
(0)

SOCS-3 shRNA Plasmid (m)

sc-41001-SHmGene SilencingPuromycin
20
(0)

SOCS-3 shRNA (m) Lentiviral Particles

sc-41001-VmGene SilencingPuromycin
20
(0)

SOCS-3 siRNA (r)

sc-270156rGene SilencingN/A
1
(0)

SOCS-3 shRNA Plasmid (r)

sc-270156-SHrGene SilencingPuromycin
1
(0)

SOCS-3 shRNA (r) Lentiviral Particles

sc-270156-VrGene SilencingPuromycin
1
(0)