SOCS-3 Antibody (G-5): sc-518020
- SOCS-3 Antibody (G-5) is a mouse monoclonal IgG1 κ, cited in 8 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 200-225 at the C-terminus of SOCS-3 of mouse origin
- Anti-SOCS-3 Antibody (G-5) is recommended for detection of SOCS-3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-SOCS-3 Antibody (G-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SOCS-3 Antibody (G-5) for WB and IHC(P) applications. These reagents are now offered in bundles with SOCS-3 Antibody (G-5) (see ordering information below).
SOCS-3 Antibody (G-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects SOCS-3 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). SOCS-3 (G-5) antibody is available in both non-conjugated and multiple conjugated forms, such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates. SOCS-3 plays a crucial role in the negative regulation of cytokine signaling, which is vital for maintaining immune homeostasis and preventing excessive inflammatory responses. SOCS-3 is primarily located in the cytoplasm, where SOCS-3 interacts with various signaling pathways, including those activated by interleukin-6 (IL-6). SOCS-3′s ability to inhibit these pathways is essential for controlling the duration and intensity of cytokine signaling, thereby preventing chronic inflammation and autoimmune diseases. Additionally, SOCS-3 undergoes post-translational modifications, such as phosphorylation, which can influence SOCS-3′s stability and activity, further underscoring SOCS-3′s importance in cellular signaling networks.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SOCS-3 Antibody (G-5) | sc-518020 | 200 µg/ml | $316.00 | |||
SOCS-3 Antibody (G-5): m-IgG Fc BP-HRP Bundle | sc-531596 | 200 µg Ab; 10 µg BP | $354.00 | |||
SOCS-3 Antibody (G-5): m-IgGκ BP-HRP Bundle | sc-525328 | 200 µg Ab, 40 µg BP | $354.00 | |||
SOCS-3 Antibody (G-5): m-IgG1 BP-HRP Bundle | sc-544648 | 200 µg Ab; 20 µg BP | $354.00 | |||
SOCS-3 Antibody (G-5) AC | sc-518020 AC | 500 µg/ml, 25% agarose | $416.00 | |||
SOCS-3 Antibody (G-5) HRP | sc-518020 HRP | 200 µg/ml | $316.00 | |||
SOCS-3 Antibody (G-5) FITC | sc-518020 FITC | 200 µg/ml | $330.00 | |||
SOCS-3 Antibody (G-5) PE | sc-518020 PE | 200 µg/ml | $343.00 | |||
SOCS-3 Antibody (G-5) Alexa Fluor® 488 | sc-518020 AF488 | 200 µg/ml | $357.00 | |||
SOCS-3 Antibody (G-5) Alexa Fluor® 546 | sc-518020 AF546 | 200 µg/ml | $357.00 | |||
SOCS-3 Antibody (G-5) Alexa Fluor® 594 | sc-518020 AF594 | 200 µg/ml | $357.00 | |||
SOCS-3 Antibody (G-5) Alexa Fluor® 647 | sc-518020 AF647 | 200 µg/ml | $357.00 | |||
SOCS-3 Antibody (G-5) Alexa Fluor® 680 | sc-518020 AF680 | 200 µg/ml | $357.00 | |||
SOCS-3 Antibody (G-5) Alexa Fluor® 790 | sc-518020 AF790 | 200 µg/ml | $357.00 |