HPV11 E7 Antibody (711-45): sc-66146

HPV11 E7 Antibody (711-45) is a mouse monoclonal IgG2a antibody that detects HPV11 E7 in HPV by enzyme-linked immunosorbent assay (ELISA). HPV11 E7 plays a crucial role in the life cycle of the human papillomavirus, particularly in manipulating host cell functions to promote viral replication and persistence. HPV11 E7 is primarily located in the nucleus of infected cells, where HPV11 E7 interacts with key regulatory proteins to disrupt normal cell cycle control. Through binding to the retinoblastoma protein (pRB), HPV11 E7 effectively inhibits tumor-suppressive functions, leading to unregulated progression through the cell cycle. This mechanism allows the virus to evade the host′s immune response and establish a productive infection, which can contribute to the development of benign lesions. Understanding HPV11 E7 function and localization is essential for developing targeted therapies and vaccines against HPV-related diseases, particularly since HPV11 E7 interactions with cellular pathways are critical for viral pathogenesis. Anti-HPV11 E7 antibody (711-45) serves as an invaluable tool for researchers studying the molecular mechanisms of HPV infection and implications in cervical cancer.

The preferred HPV11 E7 antibody is HPV11 E7 Antibody (711-13): sc-66145.