HPV18 E6 Antibody (289-13965): sc-57835
- HPV18 E6 Antibody (289-13965) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- raised against purified HPV18 E6-β-galactosidase fusion protein
- recommended for detection of by WB, IP, IF and IHC(P)
- See HPV16 E6/18 E6 (C1P5): sc-460 for HPV18 E6 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HPV18 E6 Antibody (289-13965) for WB and IHC(P) applications. These reagents are now offered in bundles with HPV18 E6 Antibody (289-13965) (see ordering information below).
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HPV18 E6 Antibody (289-13965) is a mouse monoclonal IgG1 antibody that detects HPV18 E6 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). HPV18 E6 plays a crucial role in the oncogenic process associated with high-risk human papillomavirus infections, particularly in cervical cancer. HPV18 E6 functions primarily by binding to the tumor suppressor protein p53, leading to its degradation and disruption of normal cell cycle regulation. The ability of HPV18 E6 to inactivate p53 is significant because p53 is often referred to as the "guardian of the genome," as p53 helps prevent the proliferation of cells with damaged DNA. By evading the protective effects of p53, HPV18 E6 contributes to the accumulation of genetic mutations and cancer progression. Anti-HPV18 E6 antibody (289-13965) is essential for researchers studying the molecular mechanisms of HPV-related carcinogenesis and can aid in developing targeted therapies and diagnostic tools for HPV-associated malignancies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HPV18 E6 Antibody (289-13965) | sc-57835 | 200 µg/ml | $322.00 | |||
HPV18 E6 Antibody (289-13965): m-IgG Fc BP-HRP Bundle | sc-537143 | 200 µg Ab; 10 µg BP | $361.00 | |||
HPV18 E6 Antibody (289-13965): m-IgGκ BP-HRP Bundle | sc-534337 | 200 µg Ab; 40 µg BP | $361.00 | |||
HPV18 E6 Antibody (289-13965): m-IgG1 BP-HRP Bundle | sc-545032 | 200 µg Ab; 20 µg BP | $361.00 |