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HPV18 E6 Antibody (BF7) is a mouse monoclonal IgG1 antibody that detects HPV18 E6 in HPV by applications such as western blotting (WB) and immunofluorescence (IF). HPV18 E6 plays a crucial role in the pathogenesis of cervical cancer by binding to and promoting the degradation of the p53 tumor suppressor protein, which is essential for regulating the cell cycle and preventing genomic instability. The inactivation of p53 by HPV18 E6 leads to uncontrolled cell proliferation and contributes to the malignant transformation of infected cells, making HPV18 E6 a significant target for cancer research and diagnostics. Anti-HPV18 E6 antibody (BF7) is particularly valuable for detecting HPV in cervical smears and biopsies, as well as for analyzing E6 expression in cell transformation studies, thereby aiding in the understanding of HPV-related oncogenesis and the development of potential therapeutic strategies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HPV18 E6 Antibody (BF7) | sc-53328 | 200 µg/ml | $316.00 | |||
HPV18 E6 Antibody (BF7): m-IgG Fc BP-HRP Bundle | sc-536935 | 200 µg Ab; 10 µg BP | $354.00 | |||
HPV18 E6 Antibody (BF7): m-IgGκ BP-HRP Bundle | sc-534111 | 200 µg Ab; 40 µg BP | $354.00 | |||
HPV18 E6 Antibody (BF7): m-IgG1 BP-HRP Bundle | sc-544908 | 200 µg Ab; 20 µg BP | $354.00 |