HPV11 E7 Antibody (711-66): sc-66147

HPV11 E7 Antibody (711-66) is a mouse monoclonal IgG1 antibody that detects HPV11 E7 in HPV by western blotting (WB). HPV11 E7 is a crucial oncoprotein that plays a significant role in the pathogenesis of low-risk human papillomavirus infections, particularly in the development of benign lesions such as genital warts. Understanding HPV11 E7 function is vital, as HPV11 E7 interacts with host cell regulatory proteins to disrupt normal cell cycle control, thereby promoting cellular proliferation and survival. Unlike high-risk HPV E7 proteins, which have a more pronounced impact on tumorigenesis, HPV11 E7′s interactions are primarily associated with benign outcomes, highlighting the importance of distinguishing between high-risk and low-risk HPV types in clinical settings. HPV11 E7′s ability to bind to retinoblastoma protein (pRB) is less potent compared to high-risk counterparts, which underscores the differential mechanisms of oncogenic potential among HPV types. Anti-HPV11 E7 antibody (711-66) is an essential tool for researchers studying the molecular mechanisms of HPV-related diseases and the specific roles of low-risk HPV proteins in cellular processes.

The preferred HPV11 E7 antibody is HPV11 E7 Antibody (711-13): sc-66145.