Date published: 2026-4-23

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V-ATPase Antibodies

Santa Cruz Biotechnology features a diverse variety of V-ATPase monoclonal antibodies for investigating V-ATPase's role in cellular processes. V-ATPase monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). V-ATPase, or vacuolar ATPase, is a critical enzyme complex that plays a vital role in acidifying intracellular compartments and regulating pH homeostasis. The enzyme complex is involved in numerous physiological processes, including protein sorting, neurotransmitter release, and bone resorption. V-ATPase dysfunction has been linked to various pathological conditions, making it an important focus in biomedical research. Understanding V-ATPase's molecular mechanisms and regulatory pathways can provide valuable insights into disease development and potential therapeutic strategies. Researchers can utilize V-ATPase monoclonal antibodies to explore protein localization, expression patterns, and interactions within cellular pathways. V-ATPase monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance scientific understanding of cellular pH regulation and its impact on human health.

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V-ATPase Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

V-ATPase α1 Antibody (4F5)

sc-293336mouse IgG1 κ508-617 (h)WB, IP, IF, IHC(P), FCM, ELISAm, r, h
4
(1)

V-ATPase A1 Antibody (E-8)

sc-374475mouse IgG2b κ71-210 (h)WB, IP, IF, IHC(P), ELISAm, r, h
10
(9)

V-ATPase B1/2 Antibody (D-4)

sc-271832mouse IgG1 κ103-131 (h)WB, IP, IF, IHC(P), ELISAm, r, h
7
(5)

V-ATPase B1/2 Antibody (F-6)

sc-55544mouse IgG1 κ334-513 (h)WB, IP, IF, IHC(P), ELISAm, r, h
46
(12)

V-ATPase B2 Antibody (D-11)

sc-166045mouse IgG2a κ2-38 (h)WB, IP, IF, IHC(P), ELISAm, r, h
4
(4)

V-ATPase B2 Antibody (C-9)

sc-166122mouse IgG3 κ2-38 (h)WB, IP, IF, ELISAm, r, h
4
(4)

V-ATPase B2 Antibody (F-10)

sc-515053mouse IgG1 κ1-55 (h)WB, IP, IF, ELISAm, r, h

new

(0)

V-ATPase C1 Antibody (G-5)

sc-271077mouse IgG2b κ83-382 (h)WB, IP, IF, IHC(P), ELISAm, r, h
4
(5)

V-ATPase C1 Antibody (C-2)

sc-376227mouse IgG2b κ131-169 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(3)

V-ATPase C1 Antibody (H-5)

sc-166848mouse IgG1 κ83-382 (h)WB, IP, IF, IHC(P), ELISAm, r, h
6
(2)

V-ATPase C2 Antibody (S-10)

sc-81888mouse IgG2b κ188-254 (h)WB, IP, ELISAh

new

(2)

V-ATPase D Antibody (E-12)

sc-390384mouse IgG1 κ211-249 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(3)

V-ATPase D Antibody (D-4)

sc-166218mouse IgG1 κFL (h)WB, IP, IF, ELISAm, r, h
8
(4)

V-ATPase D Antibody (A-11)

sc-390164mouse IgG2b κC-terminal (h)WB, IP, IF, ELISAm, r, h
1
(2)

V-ATPase D1 Antibody (D-4)

sc-393322mouse IgG1 κ66-105 (h)WB, IP, IF, ELISAm, r, h
2
(3)

V-ATPase D1 Antibody (34-Z)

sc-81887mouse IgG1 κ238-309 (h)WB, IP, IF, IHC(P), ELISAh
7
(5)

V-ATPase D2 Antibody (7A4)

sc-517031mouse IgG2b κ238-306 (h)WB, IP, ELISAh
5
(1)

V-ATPase G1 Antibody (D-5)

sc-25333mouse IgG1 κ39-118 (h)WB, IP, IF, IHC(P), ELISAm, r, h
8
(7)

V-ATPase G2 Antibody (A-6)

sc-25334mouse IgG2a κ39-118 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(3)

V-ATPase H Antibody (C-8)

sc-166227mouse IgG1 κ184-483 (h)WB, IP, IF, IHC(P), ELISAm, r, h
8
(3)

V-ATPase H Antibody (G-2)

sc-166059mouse IgG1 κ184-483 (h)WB, IP, IF, ELISAm, r, h
3
(1)

V-ATPase H Antibody (E-10)

sc-271186mouse IgG2a κ10-41 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(2)

V-ATPase CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

V-ATPase H CRISPR/Cas9 KO Plasmid (h)

sc-403403hGene KnockoutGFP0
(0)

V-ATPase H HDR Plasmid (h)

sc-403403-HDRhHomology Directed RepairPuromycin0
(0)

V-ATPase α1 CRISPR/Cas9 KO Plasmid (h)

sc-403882hGene KnockoutGFP0
(0)

V-ATPase α1 HDR Plasmid (h)

sc-403882-HDRhHomology Directed RepairPuromycin0
(0)

V-ATPase α1 Double Nickase Plasmid (h)

sc-403882-NIChGene KnockoutPuromycin0
(0)

V-ATPase α1 Double Nickase Plasmid (h2)

sc-403882-NIC-2hGene KnockoutPuromycin0
(0)

V-ATPase A1 CRISPR/Cas9 KO Plasmid (h)

sc-400975hGene KnockoutGFP0
(0)

V-ATPase A1 Double Nickase Plasmid (h)

sc-400975-NIChGene KnockoutPuromycin0
(0)

V-ATPase A1 Double Nickase Plasmid (h2)

sc-400975-NIC-2hGene KnockoutPuromycin0
(0)

V-ATPase B1 CRISPR/Cas9 KO Plasmid (h)

sc-400926hGene KnockoutGFP0
(0)

V-ATPase B1 HDR Plasmid (h)

sc-400926-HDRhHomology Directed RepairPuromycin0
(0)

V-ATPase B1 Double Nickase Plasmid (h)

sc-400926-NIChGene KnockoutPuromycin0
(0)

V-ATPase B1 Double Nickase Plasmid (h2)

sc-400926-NIC-2hGene KnockoutPuromycin0
(0)

V-ATPase C1 Double Nickase Plasmid (h)

sc-402679-NIChGene KnockoutPuromycin0
(0)

V-ATPase C1 Double Nickase Plasmid (h2)

sc-402679-NIC-2hGene KnockoutPuromycin0
(0)

V-ATPase D1 CRISPR/Cas9 KO Plasmid (m)

sc-419255mGene KnockoutGFP0
(0)

V-ATPase B2 Double Nickase Plasmid (h)

sc-401896-NIChGene KnockoutPuromycin0
(0)

V-ATPase B2 Double Nickase Plasmid (h2)

sc-401896-NIC-2hGene KnockoutPuromycin0
(0)

V-ATPase D2 Double Nickase Plasmid (h)

sc-404907-NIChGene KnockoutPuromycin0
(0)

V-ATPase D2 Double Nickase Plasmid (h2)

sc-404907-NIC-2hGene KnockoutPuromycin0
(0)

V-ATPase CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

V-ATPase D CRISPR Activation Plasmid (h)

sc-403291-ACThGene ActivationPuro, Blast, Hygro0
(0)

V-ATPase α1 CRISPR Activation Plasmid (h)

sc-403882-ACThGene ActivationPuro, Blast, Hygro0
(0)

V-ATPase A1 CRISPR Activation Plasmid (h)

sc-400975-ACThGene ActivationPuro, Blast, Hygro0
(0)

V-ATPase B1 CRISPR Activation Plasmid (h)

sc-400926-ACThGene ActivationPuro, Blast, Hygro0
(0)

V-ATPase C1 CRISPR Activation Plasmid (h)

sc-402679-ACThGene ActivationPuro, Blast, Hygro0
(0)

V-ATPase D1 CRISPR Activation Plasmid (h)

sc-403669-ACThGene ActivationPuro, Blast, Hygro0
(0)

V-ATPase G1 CRISPR Activation Plasmid (h)

sc-406125-ACThGene ActivationPuro, Blast, Hygro0
(0)

V-ATPase G1 CRISPR Activation Plasmid (h2)

sc-406125-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

V-ATPase G1 Lentiviral Activation Particles (h)

sc-406125-LAChGene ActivationPuro, Blast, Hygro0
(0)

V-ATPase G1 Lentiviral Activation Particles (h2)

sc-406125-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

V-ATPase A2 CRISPR Activation Plasmid (h)

sc-406000-ACThGene ActivationPuro, Blast, Hygro0
(0)

V-ATPase B2 CRISPR Activation Plasmid (h)

sc-401896-ACThGene ActivationPuro, Blast, Hygro0
(0)

V-ATPase siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

V-ATPase D siRNA (h)

sc-36791hGene SilencingN/A0
(0)

V-ATPase D shRNA Plasmid (h)

sc-36791-SHhGene SilencingPuromycin0
(0)

V-ATPase D shRNA (h) Lentiviral Particles

sc-36791-VhGene SilencingPuromycin0
(0)

V-ATPase D siRNA (m)

sc-36792mGene SilencingN/A0
(0)

V-ATPase D shRNA Plasmid (m)

sc-36792-SHmGene SilencingPuromycin0
(0)

V-ATPase D shRNA (m) Lentiviral Particles

sc-36792-VmGene SilencingPuromycin0
(0)

V-ATPase F siRNA (h)

sc-36795hGene SilencingN/A0
(0)

V-ATPase F shRNA Plasmid (h)

sc-36795-SHhGene SilencingPuromycin0
(0)

V-ATPase F shRNA (h) Lentiviral Particles

sc-36795-VhGene SilencingPuromycin0
(0)

V-ATPase F siRNA (m)

sc-36796mGene SilencingN/A0
(0)

V-ATPase F shRNA Plasmid (m)

sc-36796-SHmGene SilencingPuromycin0
(0)

V-ATPase F shRNA (m) Lentiviral Particles

sc-36796-VmGene SilencingPuromycin0
(0)

V-ATPase H siRNA (h)

sc-36801hGene SilencingN/A0
(0)

V-ATPase H shRNA Plasmid (h)

sc-36801-SHhGene SilencingPuromycin0
(0)

V-ATPase H shRNA (h) Lentiviral Particles

sc-36801-VhGene SilencingPuromycin0
(0)

V-ATPase H siRNA (m)

sc-36802mGene SilencingN/A0
(0)

V-ATPase H shRNA Plasmid (m)

sc-36802-SHmGene SilencingPuromycin0
(0)

V-ATPase H shRNA (m) Lentiviral Particles

sc-36802-VmGene SilencingPuromycin0
(0)

V-ATPase α1 siRNA (h)

sc-63199hGene SilencingN/A0
(0)

V-ATPase α1 shRNA Plasmid (h)

sc-63199-SHhGene SilencingPuromycin0
(0)

V-ATPase α1 shRNA (h) Lentiviral Particles

sc-63199-VhGene SilencingPuromycin0
(0)

V-ATPase α1 siRNA (m)

sc-63200mGene SilencingN/A0
(0)

V-ATPase α1 shRNA Plasmid (m)

sc-63200-SHmGene SilencingPuromycin0
(0)

V-ATPase α1 shRNA (m) Lentiviral Particles

sc-63200-VmGene SilencingPuromycin0
(0)

V-ATPase A1 siRNA (h)

sc-42686hGene SilencingN/A
1
(0)

V-ATPase A1 shRNA Plasmid (h)

sc-42686-SHhGene SilencingPuromycin
1
(0)

V-ATPase A1 shRNA (h) Lentiviral Particles

sc-42686-VhGene SilencingPuromycin
1
(0)

V-ATPase A1 siRNA (m)

sc-42687mGene SilencingN/A0
(0)

V-ATPase A1 shRNA Plasmid (m)

sc-42687-SHmGene SilencingPuromycin0
(0)

V-ATPase A1 shRNA (m) Lentiviral Particles

sc-42687-VmGene SilencingPuromycin0
(0)

V-ATPase B1 siRNA (h)

sc-36787hGene SilencingN/A
2
(0)

V-ATPase B1 shRNA Plasmid (h)

sc-36787-SHhGene SilencingPuromycin
2
(0)

V-ATPase B1 shRNA (h) Lentiviral Particles

sc-36787-VhGene SilencingPuromycin
2
(0)

V-ATPase B1 siRNA (m)

sc-36788mGene SilencingN/A0
(0)

V-ATPase B1 shRNA Plasmid (m)

sc-36788-SHmGene SilencingPuromycin0
(0)

V-ATPase B1 shRNA (m) Lentiviral Particles

sc-36788-VmGene SilencingPuromycin0
(0)

V-ATPase C1 siRNA (h)

sc-36789hGene SilencingN/A
1
(0)

V-ATPase C1 shRNA Plasmid (h)

sc-36789-SHhGene SilencingPuromycin
1
(0)

V-ATPase C1 shRNA (h) Lentiviral Particles

sc-36789-VhGene SilencingPuromycin
1
(0)

V-ATPase C1 siRNA (m)

sc-36790mGene SilencingN/A0
(0)

V-ATPase C1 shRNA Plasmid (m)

sc-36790-SHmGene SilencingPuromycin0
(0)

V-ATPase C1 shRNA (m) Lentiviral Particles

sc-36790-VmGene SilencingPuromycin0
(0)

V-ATPase D1 siRNA (h)

sc-63207hGene SilencingN/A
1
(0)

V-ATPase D1 shRNA Plasmid (h)

sc-63207-SHhGene SilencingPuromycin
1
(0)

V-ATPase D1 shRNA (h) Lentiviral Particles

sc-63207-VhGene SilencingPuromycin
1
(0)

V-ATPase D1 siRNA (m)

sc-63208mGene SilencingN/A0
(0)

V-ATPase D1 shRNA Plasmid (m)

sc-63208-SHmGene SilencingPuromycin0
(0)

V-ATPase D1 shRNA (m) Lentiviral Particles

sc-63208-VmGene SilencingPuromycin0
(0)

V-ATPase G1 siRNA (h)

sc-36797hGene SilencingN/A
2
(0)

V-ATPase G1 shRNA Plasmid (h)

sc-36797-SHhGene SilencingPuromycin
2
(0)

V-ATPase G1 shRNA (h) Lentiviral Particles

sc-36797-VhGene SilencingPuromycin
2
(0)

V-ATPase G1 siRNA (m)

sc-36798mGene SilencingN/A0
(0)

V-ATPase G1 shRNA Plasmid (m)

sc-36798-SHmGene SilencingPuromycin0
(0)

V-ATPase G1 shRNA (m) Lentiviral Particles

sc-36798-VmGene SilencingPuromycin0
(0)

V-ATPase A2 siRNA (h)

sc-63201hGene SilencingN/A0
(0)

V-ATPase A2 shRNA Plasmid (h)

sc-63201-SHhGene SilencingPuromycin0
(0)

V-ATPase A2 shRNA (h) Lentiviral Particles

sc-63201-VhGene SilencingPuromycin0
(0)

V-ATPase A2 siRNA (m)

sc-63202mGene SilencingN/A0
(0)

V-ATPase A2 shRNA Plasmid (m)

sc-63202-SHmGene SilencingPuromycin0
(0)

V-ATPase A2 shRNA (m) Lentiviral Particles

sc-63202-VmGene SilencingPuromycin0
(0)

V-ATPase B2 siRNA (h)

sc-43517hGene SilencingN/A0
(0)

V-ATPase B2 shRNA Plasmid (h)

sc-43517-SHhGene SilencingPuromycin0
(0)

V-ATPase B2 shRNA (h) Lentiviral Particles

sc-43517-VhGene SilencingPuromycin0
(0)

V-ATPase B2 siRNA (m)

sc-43518mGene SilencingN/A0
(0)

V-ATPase B2 shRNA Plasmid (m)

sc-43518-SHmGene SilencingPuromycin0
(0)

V-ATPase B2 shRNA (m) Lentiviral Particles

sc-43518-VmGene SilencingPuromycin0
(0)

V-ATPase C2 siRNA (h)

sc-63205hGene SilencingN/A0
(0)

V-ATPase C2 shRNA Plasmid (h)

sc-63205-SHhGene SilencingPuromycin0
(0)

V-ATPase C2 shRNA (h) Lentiviral Particles

sc-63205-VhGene SilencingPuromycin0
(0)

V-ATPase C2 siRNA (m)

sc-63206mGene SilencingN/A0
(0)

V-ATPase C2 shRNA Plasmid (m)

sc-63206-SHmGene SilencingPuromycin0
(0)

V-ATPase C2 shRNA (m) Lentiviral Particles

sc-63206-VmGene SilencingPuromycin0
(0)

V-ATPase D2 siRNA (h)

sc-76885hGene SilencingN/A0
(0)

V-ATPase D2 shRNA Plasmid (h)

sc-76885-SHhGene SilencingPuromycin0
(0)

V-ATPase D2 shRNA (h) Lentiviral Particles

sc-76885-VhGene SilencingPuromycin0
(0)

V-ATPase D2 siRNA (m)

sc-76886mGene SilencingN/A0
(0)

V-ATPase D2 shRNA Plasmid (m)

sc-76886-SHmGene SilencingPuromycin0
(0)

V-ATPase D2 shRNA (m) Lentiviral Particles

sc-76886-VmGene SilencingPuromycin0
(0)

V-ATPase E2 siRNA (m)

sc-154964mGene SilencingN/A0
(0)

V-ATPase E2 shRNA Plasmid (m)

sc-154964-SHmGene SilencingPuromycin0
(0)

V-ATPase E2 shRNA (m) Lentiviral Particles

sc-154964-VmGene SilencingPuromycin0
(0)

V-ATPase G2 siRNA (h)

sc-36799hGene SilencingN/A0
(0)

V-ATPase G2 shRNA Plasmid (h)

sc-36799-SHhGene SilencingPuromycin0
(0)

V-ATPase G2 shRNA (h) Lentiviral Particles

sc-36799-VhGene SilencingPuromycin0
(0)

V-ATPase G2 siRNA (m)

sc-36800mGene SilencingN/A0
(0)

V-ATPase G2 shRNA Plasmid (m)

sc-36800-SHmGene SilencingPuromycin0
(0)

V-ATPase G2 shRNA (m) Lentiviral Particles

sc-36800-VmGene SilencingPuromycin0
(0)

V-ATPase G3 siRNA (h)

sc-63209hGene SilencingN/A0
(0)

V-ATPase G3 shRNA Plasmid (h)

sc-63209-SHhGene SilencingPuromycin0
(0)

V-ATPase G3 shRNA (h) Lentiviral Particles

sc-63209-VhGene SilencingPuromycin0
(0)

V-ATPase G3 siRNA (m)

sc-63210mGene SilencingN/A0
(0)

V-ATPase G3 shRNA Plasmid (m)

sc-63210-SHmGene SilencingPuromycin0
(0)

V-ATPase G3 shRNA (m) Lentiviral Particles

sc-63210-VmGene SilencingPuromycin0
(0)

V-ATPase A4 siRNA (h)

sc-63203hGene SilencingN/A0
(0)

V-ATPase A4 shRNA Plasmid (h)

sc-63203-SHhGene SilencingPuromycin0
(0)

V-ATPase A4 shRNA (h) Lentiviral Particles

sc-63203-VhGene SilencingPuromycin0
(0)

V-ATPase A4 siRNA (m)

sc-63204mGene SilencingN/A0
(0)

V-ATPase A4 shRNA Plasmid (m)

sc-63204-SHmGene SilencingPuromycin0
(0)

V-ATPase A4 shRNA (m) Lentiviral Particles

sc-63204-VmGene SilencingPuromycin0
(0)