Date published: 2025-10-18

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SR-2C Activators

SR-2C activators represent a specific chemical class characterized by their ability to modulate the activity of the serotonin receptor subtype 2C, abbreviated as 5-HT2C. These receptors belong to the broader family of serotonin receptors, which are proteins found in the central nervous system and peripheral tissues, playing a pivotal role in regulating various physiological and neurological functions. The SR-2C activators interact with the 5-HT2C receptor, which is a G-protein coupled receptor (GPCR), and they do so in a manner that can either enhance or inhibit its signaling pathways. This modulation of receptor activity is essential for understanding the intricate neurochemical processes that influence mood, behavior, and other physiological responses. Chemically, SR-2C activators encompass a diverse array of compounds, including small organic molecules, peptides, and even natural products. Their interaction with the 5-HT2C receptor may result in either an agonistic or antagonistic effect, leading to changes in downstream signaling pathways. Such modulation can have profound implications for various physiological functions, as the 5-HT2C receptor is involved in the regulation of appetite, mood, and sleep, among other processes. The intricate mechanisms underlying the interaction between SR-2C activators and the 5-HT2C receptor continue to be a subject of intensive research, shedding light on the complex neurobiology of serotonin receptors.

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Items 1 to 10 of 26 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

RU 24969 hemisuccinate

107008-28-6sc-204896
sc-204896A
10 mg
50 mg
$97.00
$548.00
(0)

RU 24969 hemisuccinate, classified as an SR-2C, exhibits remarkable reactivity through its unique ester functionalities, which facilitate specific interactions with nucleophiles. The compound's structural flexibility allows for dynamic conformational changes, enhancing its ability to engage in diverse reaction pathways. Its distinctive electronic characteristics promote selective reactivity, enabling the formation of stable intermediates that can lead to complex synthetic transformations.

SKF 38393 hydrochloride

62717-42-4sc-203264
25 mg
$49.00
(1)

SKF 38393 hydrochloride, categorized as an SR-2C, showcases intriguing properties due to its unique amine and aromatic interactions. The compound's ability to form hydrogen bonds enhances its solubility and reactivity in various environments. Its distinct electronic distribution allows for selective binding to target sites, influencing reaction kinetics and pathways. Additionally, the presence of halide ions contributes to its stability and reactivity, facilitating diverse chemical transformations.

Fluoxetine

54910-89-3sc-279166
500 mg
$312.00
9
(1)

Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that may indirectly modulate 5-HT2C receptor activity by increasing serotonin levels.

Eltoprazine hydrochloride

98224-03-4sc-203574
sc-203574A
10 mg
50 mg
$125.00
$471.00
(1)

Eltoprazine hydrochloride, classified as an SR-2C, exhibits notable characteristics stemming from its intricate molecular structure. The compound's unique arrangement of functional groups promotes specific steric interactions, which can influence its reactivity and selectivity in chemical processes. Its capacity for forming coordination complexes with metal ions enhances its stability, while the presence of halide ions can modulate its electronic properties, leading to varied reaction mechanisms and pathways.

(±)α-Methylserotonin maleate

304-52-9sc-201134
sc-201134A
10 mg
50 mg
$67.00
$291.00
(0)

(±)α-Methylserotonin maleate, an SR-2C compound, showcases intriguing molecular dynamics due to its chiral centers and functional group orientation. This configuration facilitates unique hydrogen bonding interactions, influencing solubility and reactivity. The compound's ability to engage in π-π stacking with aromatic systems can alter its electronic distribution, potentially affecting reaction kinetics. Additionally, its maleate salt form enhances stability and solvation characteristics, impacting its behavior in various environments.

Clozapine

5786-21-0sc-200402
sc-200402A
50 mg
500 mg
$68.00
$357.00
11
(1)

Clozapine binds to various neurotransmitter receptors, including 5-HT2C.

Oxymetazoline Hydrochloride

2315-02-8sc-203172B
sc-203172
sc-203172C
sc-203172A
1 g
5 g
10 g
25 g
$93.00
$155.00
$360.00
$600.00
2
(0)

Oxymetazoline Hydrochloride, classified as an SR-2C compound, exhibits notable electrostatic interactions due to its quaternary ammonium structure, which enhances its affinity for specific receptors. This compound's unique steric configuration allows for selective binding, influencing its conformational dynamics. Furthermore, its solubility profile is affected by ionic interactions, which can modulate its diffusion rates in various media, thereby impacting its overall reactivity and stability in diverse chemical environments.

WAY 629 hydrochloride

57756-45-3sc-204393
sc-204393A
10 mg
50 mg
$129.00
$548.00
(0)

WAY 629 hydrochloride, categorized as an SR-2C compound, demonstrates intriguing hydrogen bonding capabilities that facilitate its interaction with target molecules. Its unique structural features promote specific conformational changes, enhancing its reactivity in various chemical pathways. Additionally, the compound's hydrophilic characteristics influence its solvation dynamics, affecting its kinetic behavior and stability in different environments, which can lead to varied reaction outcomes.

MK 212 hydrochloride

64022-27-1sc-203634
sc-203634A
10 mg
50 mg
$115.00
$473.00
(0)

MK 212 hydrochloride, classified as an SR-2C compound, exhibits notable electron-donating properties that enhance its reactivity in nucleophilic substitution reactions. Its distinct steric configuration allows for selective interactions with electrophiles, leading to unique reaction pathways. The compound's polar nature contributes to its solubility in various solvents, influencing its diffusion rates and reactivity profiles, which can result in diverse chemical transformations under varying conditions.

Olanzapine

132539-06-1sc-212469
100 mg
$130.00
6
(1)

Olanzapine is an atypical antipsychotic that has a high affinity for the 5-HT2C receptor, which may contribute to its pharmacological profile.