Date published: 2025-10-18

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SR-2C Inhibitors

SR-2C inhibitors, also known as serotonin receptor 2C inhibitors, belong to a specific chemical class of compounds that are primarily designed to modulate the activity of the serotonin 2C receptor subtype in the human brain. The serotonin 2C receptor, abbreviated as 5-HT2C receptor, is a member of the G-protein coupled receptor (GPCR) family and is involved in the regulation of various physiological processes, including mood, appetite, and sleep. SR-2C inhibitors are characterized by their ability to selectively bind to and influence the function of these receptors, either by blocking or stimulating their activity, thus altering the downstream signaling pathways. These inhibitors are typically small organic molecules with a structure that allows them to interact with the serotonin 2C receptor in a specific manner. The binding of SR-2C inhibitors to the receptor can lead to diverse pharmacological effects, depending on their mode of action. Some compounds act as antagonists, effectively preventing serotonin or other endogenous ligands from binding to the receptor, thereby reducing its activation. Others may function as agonists, mimicking the effects of serotonin and activating the receptor. The modulation of 5-HT2C receptor activity by these inhibitors can have profound effects on the brain's neurotransmitter systems, leading to alterations in mood, appetite, and other behaviors. Consequently, SR-2C inhibitors represent a class of compounds that are of interest to researchers studying the neurobiology of mood and appetite regulation

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Items 1 to 10 of 27 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Clozapine

5786-21-0sc-200402
sc-200402A
50 mg
500 mg
$68.00
$357.00
11
(1)

Clozapine, an SR-2C compound, features a complex structure that facilitates unique intermolecular interactions. The presence of a dibenzodiazepine core contributes to its distinctive electronic distribution, promoting specific hydrogen bonding and π-π stacking with other molecules. Its rigid framework and varied substituents enable selective reactivity pathways, making it an interesting subject for exploring kinetic behaviors and molecular recognition phenomena in diverse chemical environments.

S(−)-Propranolol hydrochloride

4199-10-4sc-200153
100 mg
$102.00
4
(1)

S(-)-Propranolol hydrochloride, classified as an SR-2C compound, exhibits intriguing stereochemical properties that influence its interactions at the molecular level. The chiral center enhances its ability to engage in specific stereospecific reactions, leading to unique conformational dynamics. Its hydrophilic and lipophilic balance allows for versatile solubility profiles, affecting diffusion rates and reactivity in various solvents. This compound's distinct spatial arrangement also facilitates selective binding interactions, making it a subject of interest in studies of molecular recognition and reaction kinetics.

Clozapine-d8

1185053-50-2sc-217944
sc-217944A
1 mg
10 mg
$306.00
$2050.00
(1)

Clozapine-d8, an SR-2C compound, features a deuterated structure that alters its vibrational spectra, providing insights into molecular dynamics. The presence of deuterium enhances its stability and influences reaction kinetics, particularly in hydrogen isotope effects. Its unique electronic configuration allows for distinct interactions with nucleophiles, potentially modifying reaction pathways. Additionally, the compound's isotopic labeling aids in tracing metabolic pathways, offering valuable data in mechanistic studies.

Spiperone hydrochloride

2022-29-9sc-204293
50 mg
$173.00
(1)

Spiperone hydrochloride, classified as an SR-2C compound, exhibits intriguing molecular interactions due to its unique structural features. The compound's electron-rich regions facilitate strong π-π stacking interactions, influencing its solubility and aggregation behavior. Its hydrophilic and lipophilic balance allows for diverse interactions with various solvents, affecting reaction kinetics. Additionally, the presence of halide ions can modulate its reactivity, leading to distinct pathways in chemical transformations.

Cyproheptadine hydrochloride

969-33-5sc-203557
50 mg
$87.00
2
(0)

Cyproheptadine hydrochloride, as an SR-2C compound, showcases notable conformational flexibility, allowing it to adopt multiple spatial arrangements that influence its reactivity. The presence of nitrogen atoms in its structure enhances hydrogen bonding capabilities, which can significantly alter its interaction with polar solvents. This compound also demonstrates unique charge distribution, affecting its electrophilic and nucleophilic behavior in various chemical environments, leading to diverse reaction pathways.

Oxymetazoline Hydrochloride

2315-02-8sc-203172B
sc-203172
sc-203172C
sc-203172A
1 g
5 g
10 g
25 g
$93.00
$155.00
$360.00
$600.00
2
(0)

Oxymetazoline Hydrochloride, classified as an SR-2C compound, exhibits intriguing stereoelectronic properties that facilitate specific molecular interactions. Its aromatic ring system contributes to π-π stacking, enhancing stability in certain environments. The compound's ability to engage in dipole-dipole interactions, due to its functional groups, influences solubility and reactivity. Additionally, its unique spatial orientation can affect reaction kinetics, leading to distinct pathways in chemical transformations.

Camostat mesylate

59721-29-8sc-203867
sc-203867A
sc-203867B
sc-203867C
sc-203867D
sc-203867E
10 mg
50 mg
500 mg
1 g
10 g
100 g
$42.00
$179.00
$306.00
$612.00
$2040.00
$4386.00
5
(0)

Camostat inhibits the host cell serine protease TMPRSS2, which is required for viral entry and fusion of SARS-CoV-2.

Puerarin

3681-99-0sc-202301
sc-202301A
5 mg
100 mg
$129.00
$205.00
1
(0)

Puerarin, categorized as an SR-2C compound, showcases remarkable hydrogen bonding capabilities that enhance its solubility in polar solvents. Its structural features allow for strong interactions with water molecules, promoting unique solvation dynamics. The compound's ability to form stable complexes with metal ions can influence catalytic processes. Furthermore, its conformational flexibility may lead to varied reaction pathways, impacting overall reactivity and selectivity in chemical reactions.

N-Desmethylclozapine

6104-71-8sc-201113
sc-201113A
5 mg
25 mg
$98.00
$364.00
2
(0)

N-Desmethylclozapine, identified as an SR-2C compound, exhibits intriguing electron-donating properties due to its unique nitrogen-containing structure. This facilitates strong π-π stacking interactions, enhancing its stability in various environments. The compound's hydrophobic regions contribute to its partitioning behavior, influencing its distribution in mixed-phase systems. Additionally, its reactivity profile is characterized by selective electrophilic attack, which can lead to diverse synthetic pathways.

Ketanserin

74050-98-9sc-279249
1 g
$700.00
(0)

Ketanserin, classified as an SR-2C compound, showcases distinctive hydrophilic and lipophilic characteristics that influence its solubility and interaction with biological membranes. Its unique aromatic framework allows for significant hydrogen bonding and dipole-dipole interactions, enhancing its affinity for specific targets. The compound's kinetic behavior is marked by rapid conformational changes, which can affect its reactivity and stability in various chemical environments, leading to diverse reaction pathways.