Oxymetazoline Hydrochloride is a direct sympathomimetic agent. Is a nonselective adrenomimetic of α1A-AR and α2A-AR (α1-AR and α2-AR adrenergic receptor) agonists. Since vascular beds widely express α1 receptors, the action of Oxymetazoline results in vasoconstriction due to its action on endothelial α2 receptors. Oxymetazoline Hydrochloride is an inhibitor of SR-2C and an activator of SR-1A, SR-1B, SR-1D and SR-2C.
1. Schoeffter, P., et al. 1991. Eur. J. Pharmacol. 196: 213-216. PMID: 1678720 2. Horie, K., et al. 1995. Br. J. Pharmacol. 116: 1611-1618. PMID: 8564227 3. Widdicombe, J. 1997. Allergy. 52: 7-11. PMID: 9353554 4. Bayorh, M.A., et al. 1997. Clin. Exp. Hypertens. 18: 445-460. PMID: 9140707
Soluble in water (50 mg/ml), alcohol (1: 3.6), methanol, DMSO (59 mg/ml), and ethanol (59 mg/ml).
RE:Oxymetazoline Hydrochloride, 5 g sc-203172 - What is the purity of this chemical?
Asked by: Anonymous
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate Of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate Of Analysis on our website. The purity of the most recent lot for sc-203172 is 99.9%.
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