Molecular structure of Eltoprazine hydrochloride, CAS Number: 98224-03-4
Eltoprazine hydrochloride (CAS 98224-03-4)
Alternate Names:
1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine hydrochloride
Application:
Eltoprazine hydrochloride is a partial agonist at SR-1 and SR-2C
CAS Number:
98224-03-4
Purity:
≥98%
Molecular Weight:
256.73
Molecular Formula:
C12H16N2O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
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SDS & Certificate of Analysis
Eltoprazine hydrochloride is a SR-1 and SR-2C receptor partial agonist (Ki values are 40, 52 and 81 nM for SR-1A, SR-1B and SR-2C, respectively). HCl content varies. Please refer to Certificate of Analysis for specific lot content.
Eltoprazine hydrochloride (CAS 98224-03-4) References
- Food intake and rumen motility in dwarf goats. Effects of some serotonin receptor agonists and antagonists. | Kaya, F., et al. 1992. Vet Res Commun. 16: 379-90. PMID: 1494862
- Effects of eltoprazine hydrochloride on exploratory behavior and social attraction in mice. | Kemble, ED., et al. 1991. Pharmacol Biochem Behav. 38: 759-62. PMID: 1871192
- The actions of the novel anti-aggressive drug eltoprazine on central neurones in the anaesthetised rat. | Evans, SM., et al. 1990. Neuropharmacology. 29: 895-900. PMID: 1979428
- Pharmacokinetics of eltoprazine in the dog. | Lammers, R. and van Harten, J. 1990. Drug Metabol Drug Interact. 8: 141-8. PMID: 2091887
- Behavioural pharmacology of the serenic, eltoprazine. | Olivier, B., et al. 1990. Drug Metabol Drug Interact. 8: 31-83. PMID: 2091890
- Pharmacokinetic evaluation of eltoprazine. | Wigal, SB. and Duong, S. 2011. Expert Opin Drug Metab Toxicol. 7: 775-81. PMID: 21548716
- Pharmacokinetics of eltoprazine in healthy male subjects after single dose oral and intravenous administration. | Raghoebar, M., et al. 1990. Br J Clin Pharmacol. 30: 879-83. PMID: 2288834
- Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson's disease: a dose-finding study. | Svenningsson, P., et al. 2015. Brain. 138: 963-73. PMID: 25669730
- The development of 2-acetylphenol-donepezil hybrids as multifunctional agents for the treatment of Alzheimer's disease. | Zhu, G., et al. 2019. Bioorg Med Chem Lett. 29: 126625. PMID: 31444085
- Serotonin receptors and animal models of aggressive behavior. | Olivier, B., et al. 1995. Pharmacopsychiatry. 28 Suppl 2: 80-90. PMID: 8614705
Activator of:
SR-1A, SR-1B, and SR-2C.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Eltoprazine hydrochloride, 10 mg | sc-203574 | 10 mg | $125.00 | |||
Eltoprazine hydrochloride, 50 mg | sc-203574A | 50 mg | $471.00 |