Date published: 2025-10-18

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SR-2C Activators

SR-2C activators represent a specific chemical class characterized by their ability to modulate the activity of the serotonin receptor subtype 2C, abbreviated as 5-HT2C. These receptors belong to the broader family of serotonin receptors, which are proteins found in the central nervous system and peripheral tissues, playing a pivotal role in regulating various physiological and neurological functions. The SR-2C activators interact with the 5-HT2C receptor, which is a G-protein coupled receptor (GPCR), and they do so in a manner that can either enhance or inhibit its signaling pathways. This modulation of receptor activity is essential for understanding the intricate neurochemical processes that influence mood, behavior, and other physiological responses. Chemically, SR-2C activators encompass a diverse array of compounds, including small organic molecules, peptides, and even natural products. Their interaction with the 5-HT2C receptor may result in either an agonistic or antagonistic effect, leading to changes in downstream signaling pathways. Such modulation can have profound implications for various physiological functions, as the 5-HT2C receptor is involved in the regulation of appetite, mood, and sleep, among other processes. The intricate mechanisms underlying the interaction between SR-2C activators and the 5-HT2C receptor continue to be a subject of intensive research, shedding light on the complex neurobiology of serotonin receptors.

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Items 11 to 20 of 26 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

WAY 161503 hydrochloride

276695-22-8sc-204392
sc-204392A
5 mg
25 mg
$94.00
$376.00
(1)

WAY 161503 hydrochloride, categorized as an SR-2C compound, demonstrates intriguing ligand-binding characteristics that facilitate specific interactions with target proteins. Its unique structural features promote conformational changes in molecular complexes, enhancing its reactivity in complexation reactions. The compound's hydrophilic regions improve solvation dynamics, affecting its kinetic behavior and enabling distinct pathways in chemical transformations, particularly in aqueous environments.

SCH 23390

125941-87-9sc-200408
sc-200408A
5 mg
25 mg
$175.00
$719.00
2
(1)

SCH 23390, classified as an SR-2C compound, exhibits remarkable selectivity in receptor binding, influencing downstream signaling pathways. Its unique stereochemistry allows for precise interactions with neurotransmitter systems, leading to distinct allosteric modulation. The compound's lipophilic characteristics enhance membrane permeability, while its dynamic conformational flexibility contributes to varied reaction kinetics, facilitating diverse chemical interactions in biological systems.

Ro 60-0175 fumarate

169675-09-6sc-204890
sc-204890A
10 mg
50 mg
$145.00
$615.00
(0)

Ro 60-0175 fumarate, an SR-2C compound, showcases intriguing molecular interactions through its unique binding affinity to specific receptors. Its structural conformation enables selective engagement with target sites, influencing intracellular signaling cascades. The compound's hydrophobic nature promotes effective membrane integration, while its kinetic profile reveals a propensity for rapid association and dissociation, allowing for nuanced modulation of biological responses. This dynamic behavior underscores its potential in various biochemical contexts.

CP 809101 hydrochloride

479683-64-2sc-205277
sc-205277A
10 mg
50 mg
$132.00
$559.00
(1)

CP 809101 hydrochloride, classified as an SR-2C, exhibits distinctive molecular characteristics that facilitate its interaction with specific protein targets. Its unique stereochemistry allows for precise conformational adjustments, enhancing binding efficiency. The compound's solubility profile supports effective diffusion across lipid membranes, while its reaction kinetics indicate a balanced rate of formation and breakdown, enabling fine-tuned regulatory effects in biochemical pathways. This behavior highlights its complex role in molecular interactions.

VER-3323 hemifumarate salt

sc-301968
50 mg
$650.00
(0)

VER-3323 hemifumarate salt, categorized as an SR-2C, showcases remarkable molecular dynamics that influence its reactivity and interaction with biological systems. Its unique structural features promote selective binding to target sites, while the presence of functional groups enhances its solubility in various environments. The compound's kinetic properties reveal a rapid equilibrium between its active and inactive forms, allowing for nuanced modulation of cellular processes. This intricate behavior underscores its significance in molecular chemistry.

Ketanserin

74050-98-9sc-279249
1 g
$700.00
(0)

Ketanserin is a 5-HT2A receptor antagonist that also shows affinity for the 5-HT2C receptor, and it is used to study the role of these receptors in various physiological and pathological conditions.

1-Methylpsilocin

1465-16-3sc-203764
sc-203764A
10 mg
50 mg
$204.00
$714.00
(0)

1-Methylpsilocin, classified as an SR-2C, exhibits intriguing molecular characteristics that dictate its reactivity and interaction profiles. Its unique stereochemistry facilitates specific conformational changes, enhancing its affinity for certain receptors. The compound's dynamic solvation behavior allows for effective penetration into lipid membranes, while its electron-rich structure promotes diverse intermolecular interactions. These attributes contribute to its complex kinetic pathways, influencing its overall stability and reactivity in various environments.

PNU 22394 hydrochloride

15923-78-1sc-204851
sc-204851A
10 mg
50 mg
$155.00
$615.00
(0)

PNU 22394 hydrochloride, an SR-2C compound, showcases distinctive molecular interactions that influence its reactivity. Its unique functional groups enable selective binding to target sites, while its polar nature enhances solubility in aqueous environments. The compound's ability to form stable complexes through hydrogen bonding and dipole-dipole interactions contributes to its intricate reaction kinetics. Additionally, its structural flexibility allows for diverse conformational adaptations, impacting its behavior in various chemical contexts.

Org 12962 HCl

210821-63-9sc-301505
sc-301505A
10 mg
50 mg
$139.00
$585.00
(0)

Org 12962 HCl, classified as an SR-2C, exhibits remarkable reactivity due to its electrophilic nature as an acid halide. The presence of halogen atoms facilitates nucleophilic attack, leading to rapid acylation reactions. Its unique steric configuration promotes specific interactions with nucleophiles, enhancing selectivity in synthetic pathways. Furthermore, the compound's high reactivity is complemented by its ability to stabilize transition states, influencing overall reaction rates and mechanisms.

Agomelatine

138112-76-2sc-207266
10 mg
$133.00
2
(1)

Agomelatine acts as an agonist at melatonin receptors and an antagonist at 5-HT2C receptors, modulating serotonin neurotransmission.