Date published: 2025-11-24

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Rb Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Rb Antibodies for the detection and analysis of the retinoblastoma protein (Rb). Rb Antibodies are available for various research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The retinoblastoma protein plays a crucial role in regulating the cell cycle and is a key tumor suppressor involved in preventing uncontrolled cell growth. Its function is vital for maintaining genomic stability and preventing the development of cancers, particularly retinoblastoma, a rare eye cancer that primarily affects children. Understanding the mechanisms of retinoblastoma protein regulation and function is essential for advancing cancer research and developing targeted therapies. Rb monoclonal antibodies enable detailed investigation of cell cycle checkpoints and their relationship to cancer development. Researchers can explore specific protein interactions and cellular pathways involved in tumor suppression using multiple detection methods. Santa Cruz Biotechnology monoclonal antibodies for Rb support researchers worldwide in advancing our understanding of cancer biology and developing new therapeutic strategies.

SEE ALSO...

Rb Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Rb Antibody (IF8)

sc-102mouse IgG1 κN/AWB, IP, IF, IHC(P), FCMm, r, h
384
(27)

Rb Antibody (C-2)

sc-74562mouse IgG2a κ769-921 (m)WB, IP, IF, ELISAm, r, h
37
(7)

Rb Antibody (Rb1)

sc-73598mouse IgG1 κFL (h)WB, IP, IF, IHC(P), FCMm, r, h
25
(4)

Rb Antibody (H-2)

sc-74570mouse IgG2a κ769-921 (m)WB, IP, IF, ELISAm, r, h
7
(5)

Rb Antibody (XZ55)

sc-65230mouse IgG1 κ387-982 (h)WB, IP, IFm, r, h
2
(3)

cleaved Rb Antibody (172C1094)

sc-56217mouse IgG1N/AWB, IPm, r, h

new

(1)

Phospho-Specific Rb Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-Rb Antibody (A-5)

sc-377528mouse IgG2b κSer 249/Thr 252 (h)WB, IP, IF, IHC(P), ELISAm, r, h
21
(7)

p-Rb Antibody (F-2)

sc-377539mouse IgG1 κSer 249/Thr 252 (h)WB, IP, IF, IHC(P), ELISAm, r, h
3
(2)

p-Rb Antibody (E-10)

sc-271930mouse IgG3 κThr 821/826 (h)WB, IP, IF, IHC(P), ELISAm, r, h
17
(13)

p-Rb Antibody (7F10)

sc-56175rat IgG2aTyr 356 (h)WB, IP, IFm, r, h
2
(2)

p-Rb Antibody (F-4)

sc-377540mouse IgG2a κSer 608 (h)WB, IP, IF, ELISAh
3
(3)

p-Rb Antibody (B-4)

sc-514031mouse IgM κSer 795 (h)WB, IP, IF, ELISAm, r, h
1
(7)

p-Rb Antibody (B-7)

sc-377527mouse IgG2b κThr 356 (h)WB, IP, IF, IHC(P), ELISAh
2
(4)

p-Rb Antibody (B-8)

sc-377541mouse IgG2a κThr 356 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(2)

p-Rb Antibody (C-3)

sc-377524mouse IgG2b κThr 356 (h)WB, IP, IF, IHC(P), ELISAh

new

(2)

Rb CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Rb CRISPR/Cas9 KO Plasmid (h)

sc-400116hGene KnockoutGFP
3
(0)

Rb HDR Plasmid (h)

sc-400116-HDRhHomology Directed RepairPuromycin
3
(0)

Rb Double Nickase Plasmid (h)

sc-400116-NIChGene KnockoutPuromycin
3
(0)

Rb Double Nickase Plasmid (h2)

sc-400116-NIC-2hGene KnockoutPuromycin
3
(0)

Rb CRISPR/Cas9 KO Plasmid (m)

sc-422610mGene KnockoutGFP0
(0)

Rb HDR Plasmid (m)

sc-422610-HDRmHomology Directed RepairPuromycin0
(0)

Rb Double Nickase Plasmid (m)

sc-422610-NICmGene KnockoutPuromycin0
(0)

Rb Double Nickase Plasmid (m2)

sc-422610-NIC-2mGene KnockoutPuromycin0
(0)

Rb CRISPR/Cas9 KO Plasmid (r)

sc-437319rGene KnockoutGFP0
(0)

Rb HDR Plasmid (r)

sc-437319-HDRrHomology Directed RepairPuromycin0
(0)

Rb CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Rb CRISPR Activation Plasmid (h)

sc-400116-ACThGene ActivationPuro, Blast, Hygro
3
(0)

Rb CRISPR Activation Plasmid (h2)

sc-400116-ACT-2hGene ActivationPuro, Blast, Hygro
3
(0)

Rb Lentiviral Activation Particles (h)

sc-400116-LAChGene ActivationPuro, Blast, Hygro
3
(0)

Rb Lentiviral Activation Particles (h2)

sc-400116-LAC-2hGene ActivationPuro, Blast, Hygro
3
(0)

Rb CRISPR Activation Plasmid (m)

sc-422610-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Rb CRISPR Activation Plasmid (m2)

sc-422610-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Rb Lentiviral Activation Particles (m)

sc-422610-LACmGene ActivationPuro, Blast, Hygro0
(0)

Rb Lentiviral Activation Particles (m2)

sc-422610-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Rb siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Rb siRNA (h)

sc-29468hGene SilencingN/A
17
(1)

Rb siRNA (h2)

sc-44273hGene SilencingN/A0
(0)

Rb shRNA Plasmid (h)

sc-29468-SHhGene SilencingPuromycin
17
(1)

Rb shRNA Plasmid (h2)

sc-44273-SHhGene SilencingPuromycin0
(0)

Rb shRNA (h) Lentiviral Particles

sc-29468-VhGene SilencingPuromycin
17
(1)

Rb shRNA (h2) Lentiviral Particles

sc-44273-VhGene SilencingPuromycin0
(0)

Rb siRNA (m)

sc-29469mGene SilencingN/A
3
(0)

Rb shRNA Plasmid (m)

sc-29469-SHmGene SilencingPuromycin
3
(0)

Rb shRNA (m) Lentiviral Particles

sc-29469-VmGene SilencingPuromycin
3
(0)

Rb Transfected Lysates

Empty Table HeaderProduct NameCATALOG #SpeciesCONTROL ANTIBODYCitationsRATING

Rb (h): 293T Lysate

sc-114014h0
(0)

Rb (h2): 293T Lysate

sc-159907h20
(0)

Rb Proteins

Empty Table HeaderProduct NameCATALOG #AmountSpeciesCitationsRATING

Rb (769)

sc-411250 µgm
65
(0)