p-Rb Antibody (C-3): sc-377524
- p-Rb Antibody (C-3) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- recommended for detection of Thr 356 phosphorylated Rb of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for p-Rb Antibody (C-3) for WB and IHC(P) applications. These reagents are now offered in bundles with p-Rb Antibody (C-3) (see ordering information below).
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SEE ALSO...
p-Rb Antibody (C-3) is a mouse monoclonal IgG2b antibody that detects retinoblastoma protein (Rb) in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-Rb antibody (C-3) plays a crucial role in studying Rb, which is essential for regulating cell cycle progression, differentiation, and apoptosis. Rb protein is primarily located in the nucleus, where Rb functions as a key tumor suppressor by controlling the transition from the G1 phase to the S phase of the cell cycle. Proper localization of Rb is vital, as Rb interacts with transcription factors and other regulatory proteins that govern cell proliferation. Dysregulation of Rb localization can lead to uncontrolled cell division and contribute to tumorigenesis, particularly in pediatric cancers such as retinoblastoma. The phosphorylation state of Rb, influenced by various kinases, determines Rb activity and localization, making Rb a critical focus for understanding cancer biology and developing targeted therapies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-Rb Antibody (C-3) | sc-377524 | 200 µg/ml | $316.00 | |||
p-Rb Antibody (C-3): m-IgG Fc BP-HRP Bundle | sc-538050 | 200 µg Ab; 10 µg BP | $354.00 | |||
p-Rb Antibody (C-3): m-IgGκ BP-HRP Bundle | sc-535576 | 200 µg Ab; 40 µg BP | $354.00 | |||
p-Rb Antibody (C-3): m-IgG2b BP-HRP Bundle | sc-549915 | 200 µg Ab; 10 µg BP | $354.00 | |||
p-Rb (C-3) Neutralizing Peptide | sc-377524 P | 100 µg/0.5 ml | $68.00 |