Date published: 2026-4-24

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CD137 Antibodies

Santa Cruz Biotechnology features a diverse variety of CD137 monoclonal antibodies for research focused on understanding immune system regulation. CD137 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CD137, also known as 4-1BB, is a co-stimulatory molecule that plays a critical role in T cell activation and survival, making it essential for effective immune responses. CD137 influences immune cell proliferation and differentiation, particularly in immune responses against cancer and autoimmune conditions. Understanding CD137 function continues to be crucial for developing new immunotherapies and advancing our knowledge of immune regulation. CD137 research has revealed significant insights into T cell biology and immune system modulation. Ongoing studies of CD137 signaling pathways have enhanced our understanding of immune cell communication and regulation. CD137 monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance immunology research and contribute to the development of new therapeutic strategies.

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CD137 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CD137 Antibody (BBK-2)

sc-58947mouse IgG1 κ(h)WB, IP, IF, FCMh
1
(6)

CD137 Antibody (0.N.185)

sc-70531mouse IgG1 κinternal (h)WB, IP, IF, FCMh

new

(1)

CD137 Antibody (G-1)

sc-365371mouse IgM κ33-61 (h)WB, IP, IF, ELISAh
1
(1)

CD137L Antibody (G-10)

sc-398933mouse IgM κ41-67 (m)WB, IP, IF, ELISAm, r, h
1
(2)

CD137L Antibody (ANC5D6)

sc-65279mouse IgG2a(h)WB, IP, ELISAh

new

(1)

CD137L Antibody (AT113-2)

sc-58949rat IgG1(m)WB, IP, FCMm
1
(1)

CD137L Antibody (TKS-1)

sc-53547rat IgG2aN/AFCMm

new

(1)

CD137 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD137 CRISPR/Cas9 KO Plasmid (h)

sc-405068hGene KnockoutGFP0
(0)

CD137 Double Nickase Plasmid (h)

sc-405068-NIChGene KnockoutPuromycin0
(0)

CD137 Double Nickase Plasmid (h2)

sc-405068-NIC-2hGene KnockoutPuromycin0
(0)

CD137 CRISPR/Cas9 KO Plasmid (m)

sc-423447mGene KnockoutGFP0
(0)

CD137 HDR Plasmid (m)

sc-423447-HDRmHomology Directed RepairPuromycin0
(0)

CD137L CRISPR/Cas9 KO Plasmid (h2)

sc-404974-KO-2hGene KnockoutGFP0
(0)

CD137L HDR Plasmid (h2)

sc-404974-HDR-2hHomology Directed RepairPuromycin0
(0)

CD137L Double Nickase Plasmid (h)

sc-404974-NIChGene KnockoutPuromycin0
(0)

CD137L Double Nickase Plasmid (h2)

sc-404974-NIC-2hGene KnockoutPuromycin0
(0)

CD137L CRISPR/Cas9 KO Plasmid (m)

sc-423455mGene KnockoutGFP0
(0)

CD137 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD137 CRISPR Activation Plasmid (h)

sc-405068-ACThGene ActivationPuro, Blast, Hygro0
(0)

CD137 CRISPR Activation Plasmid (m)

sc-423447-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CD137 CRISPR Activation Plasmid (m2)

sc-423447-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CD137 Lentiviral Activation Particles (m)

sc-423447-LACmGene ActivationPuro, Blast, Hygro0
(0)

CD137 Lentiviral Activation Particles (m2)

sc-423447-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CD137L CRISPR Activation Plasmid (h)

sc-404974-ACThGene ActivationPuro, Blast, Hygro0
(0)

CD137L CRISPR Activation Plasmid (h2)

sc-404974-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CD137 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD137 siRNA (h)

sc-29961hGene SilencingN/A0
(0)

CD137 shRNA Plasmid (h)

sc-29961-SHhGene SilencingPuromycin0
(0)

CD137 shRNA (h) Lentiviral Particles

sc-29961-VhGene SilencingPuromycin0
(0)

CD137 siRNA (m)

sc-42826mGene SilencingN/A0
(0)

CD137 shRNA Plasmid (m)

sc-42826-SHmGene SilencingPuromycin0
(0)

CD137 shRNA (m) Lentiviral Particles

sc-42826-VmGene SilencingPuromycin0
(0)

CD137L siRNA (h)

sc-42827hGene SilencingN/A0
(0)

CD137L shRNA Plasmid (h)

sc-42827-SHhGene SilencingPuromycin0
(0)

CD137L shRNA (h) Lentiviral Particles

sc-42827-VhGene SilencingPuromycin0
(0)

CD137L siRNA (m)

sc-42828mGene SilencingN/A0
(0)

CD137L shRNA Plasmid (m)

sc-42828-SHmGene SilencingPuromycin0
(0)

CD137L shRNA (m) Lentiviral Particles

sc-42828-VmGene SilencingPuromycin0
(0)