CD137L Antibody (ANC5D6): sc-65279
- CD137L Antibody (ANC5D6) is a mouse monoclonal IgG2a provided at 100 µg/ml
- raised against recombinant CD137L of human origin
- recommended for detection of CD137L of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD137L Antibody (ANC5D6). This work is in progress.
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CD137L Antibody (ANC5D6) is a mouse monoclonal IgG2a antibody that detects CD137L in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). CD137L, also known as 4-1BB ligand, plays a crucial role in the immune system by providing a costimulatory signal necessary for T cell activation and proliferation. CD137L is primarily expressed on antigen-presenting cells, including B cells, macrophages, and dendritic cells, where anti-CD137L antibody (ANC5D6) can detect interactions with CD137 on activated T cells. This interaction is vital for enhancing T cell responses, particularly in the context of tumor immunity and chronic infections. CD137L is involved in the regulation of immune responses, influencing the survival and function of T cells and other immune cells. The presence of soluble forms of CD137L in the serum of patients with autoimmune diseases, such as rheumatoid arthritis, suggests CD137L′s potential role in modulating immune responses and could serve as a biomarker for disease activity. CD137L monoclonal antibody (ANC5D6) is an essential tool for researchers studying T cell activation, immune regulation, and the therapeutic potential of targeting this pathway in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD137L Antibody (ANC5D6) | sc-65279 | 100 µg/ml | $322.00 |