CD137L Antibody (TKS-1): sc-53547

CD137L Antibody (TKS-1) is a rat monoclonal IgG2a antibody that detects CD137L in mouse samples through flow cytometry (FCM). CD137L, also known as 4-1BB ligand, plays a crucial role in the immune response by providing a costimulatory signal to T cells, which is essential for their activation and proliferation. CD137L is primarily expressed on antigen-presenting cells, including B cells, macrophages, and dendritic cells, where CD137L interacts with CD137 on activated T cells. The binding of CD137L to CD137 not only enhances T cell activation but also promotes the generation of cytotoxic T cells, which are vital for targeting and eliminating infected or malignant cells. Additionally, the interaction between CD137L and CD137 can influence the survival and function of peripheral monocytes, highlighting the importance of this pathway in regulating immune responses. Understanding the dynamics of CD137L and its interactions is critical for developing therapeutic strategies aimed at modulating immune responses in various diseases, including cancer and autoimmune disorders. Anti-CD137L antibody (TKS-1) is an invaluable tool for researchers investigating these complex immune mechanisms.

The preferred CD137L antibody is CD137L Antibody (G-10): sc-398933.