Date published: 2025-12-20

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caspase-8 Antibodies

Santa Cruz Biotechnology provides a broad selection of caspase-8 monoclonal antibodies for research in apoptosis and cell signaling pathways. caspase-8 Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Caspase-8 is a crucial initiator caspase that plays a significant role in the extrinsic apoptotic pathway, mediating cell death in response to death receptor signaling. The function of caspase-8 is vital for maintaining cellular homeostasis and regulating immune responses. Dysregulation of caspase-8 has been implicated in various diseases, including cancer and autoimmune disorders, making it an important target for therapeutic intervention. Understanding caspase-8 activity and regulation can provide valuable insights into disease mechanisms and potential treatment strategies. Investigating caspase-8 signaling pathways helps reveal the complex interplay between cell death and survival mechanisms. Research focusing on caspase-8 continues to advance our understanding of programmed cell death and its role in disease development. Santa Cruz Biotechnology monoclonal antibodies for caspase-8 enable researchers worldwide to advance scientific knowledge in cell death pathways and disease mechanisms.

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caspase-8 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

caspase-8 Antibody (8CSP03)

sc-56070mouse IgG1 κFL (h)WB, IP, IF, IHC(P), ELISAh
85
(22)

caspase-8 Antibody (1.1.40)

sc-81656mouse IgG1 κFL (h)WB, IPm, r, h
37
(7)

caspase-8 Antibody (2.1.24)

sc-81657mouse IgG1 κFL (h)WB, IPm, r, h
10
(2)

caspase-8 Antibody (4.1.20)

sc-73526mouse IgG1 κFL (h)WB, IP, IF, IHC(P), ELISAh
12
(2)

caspase-8 Antibody (3C121)

sc-70501mouse IgG1 κFL (h)WB, IP, IF, IHC(P)m, r, h
13
(2)

caspase-8 Antibody (8CSP01)

sc-81661mouse IgG1 κFL (h)WB, IPm, r, h
4
(3)

caspase-8 Antibody (8CSP02)

sc-81662mouse IgG1 κFL (h)WB, IPm, r, h
2
(3)

caspase-8 Antibody (4i30)

sc-70502mouse IgG1 κFL (h)WB, IP, IF, IHC(P)m, r, h
1
(1)

caspase-8 Antibody (FLICE4-1-20)

sc-56072mouse IgG1 κFL (h)WB, IP, ELISAh
1
(1)

caspase-8 p10 Antibody (C502S)

sc-56071mouse IgG1N-Terminal (h)WB, IPh
2
(1)

caspase-8 p18 Antibody (D-8)

sc-5263mouse IgG2a κ217-350 (h)WB, IP, IF, IHC(P), ELISAm, r, h
102
(5)

caspase-8 p18 Antibody (G-1)

sc-166596mouse IgG2b κ221-236 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(1)

caspase-8 p18 Antibody (E-8)

sc-166320mouse IgG3 κ221-236 (h)WB, IP, IF, IHC(P), ELISAm, r, h
12
(5)

caspase-8 p18 Antibody (D-7)

sc-393776mouse IgG2a345-374 (h)WB, IP, IF, IHC(P), ELISAm, r, h
4
(1)

caspase-8 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

caspase-8 CRISPR/Cas9 KO Plasmid (h)

sc-400147hGene KnockoutGFP
3
(0)

caspase-8 HDR Plasmid (h)

sc-400147-HDRhHomology Directed RepairPuromycin
3
(0)

caspase-8 Double Nickase Plasmid (h)

sc-400147-NIChGene KnockoutPuromycin
3
(0)

caspase-8 Double Nickase Plasmid (h2)

sc-400147-NIC-2hGene KnockoutPuromycin
3
(0)

caspase-8 CRISPR/Cas9 KO Plasmid (m2)

sc-419469-KO-2mGene KnockoutGFP0
(0)

caspase-8 HDR Plasmid (m2)

sc-419469-HDR-2mHomology Directed RepairPuromycin0
(0)

caspase-8 Double Nickase Plasmid (m)

sc-419469-NICmGene KnockoutPuromycin0
(0)

caspase-8 Double Nickase Plasmid (m2)

sc-419469-NIC-2mGene KnockoutPuromycin0
(0)

caspase-8 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

caspase-8 CRISPR Activation Plasmid (h)

sc-400147-ACThGene ActivationPuro, Blast, Hygro
3
(0)

caspase-8 CRISPR Activation Plasmid (h2)

sc-400147-ACT-2hGene ActivationPuro, Blast, Hygro
3
(0)

caspase-8 Lentiviral Activation Particles (h)

sc-400147-LAChGene ActivationPuro, Blast, Hygro
3
(0)

caspase-8 Lentiviral Activation Particles (h2)

sc-400147-LAC-2hGene ActivationPuro, Blast, Hygro
3
(0)

caspase-8 CRISPR Activation Plasmid (m)

sc-419469-ACTmGene ActivationPuro, Blast, Hygro0
(0)

caspase-8 CRISPR Activation Plasmid (m2)

sc-419469-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

caspase-8 Lentiviral Activation Particles (m)

sc-419469-LACmGene ActivationPuro, Blast, Hygro0
(0)

caspase-8 Lentiviral Activation Particles (m2)

sc-419469-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

caspase-8 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

caspase-8 siRNA (h)

sc-29930hGene SilencingN/A
24
(2)

caspase-8 shRNA Plasmid (h)

sc-29930-SHhGene SilencingPuromycin
24
(2)

caspase-8 shRNA (h) Lentiviral Particles

sc-29930-VhGene SilencingPuromycin
24
(2)

caspase-8 siRNA (m)

sc-37226mGene SilencingN/A
2
(0)

caspase-8 shRNA Plasmid (m)

sc-37226-SHmGene SilencingPuromycin
2
(0)

caspase-8 shRNA (m) Lentiviral Particles

sc-37226-VmGene SilencingPuromycin
2
(0)