Date published: 2026-5-7

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caspase-1 Antibodies

Santa Cruz Biotechnology provides a broad selection of caspase-1 monoclonal antibodies for research focused on understanding this critical enzyme. caspase-1 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Caspase-1, also known as interleukin-1 converting enzyme (ICE), plays a pivotal role in the inflammatory response by processing pro-inflammatory cytokines such as IL-1β and IL-18. The activation of caspase-1 is crucial for regulating apoptosis and pyroptosis, making it a significant target in studies related to inflammation, infection, and various diseases. Research involving caspase-1 has revealed its importance in multiple cellular pathways and signaling cascades. Understanding caspase-1 function can provide insights into therapeutic strategies for conditions such as autoimmune diseases and cancer. Investigating caspase-1 activity helps researchers better comprehend cellular responses to stress and infection. Current research continues to uncover new roles for caspase-1 in cellular processes and disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of inflammatory processes and potential therapeutic applications.

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caspase-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

caspase-1 Antibody (D-3)

sc-392736mouse IgG1 κ367-391 (h)WB, IP, IF, IHC(P), ELISAm, r, h
66
(18)

caspase-1 Antibody (14F468)

sc-56036mouse IgG1 κ371-390 (h)WB, IP, IF, IHC(P)m, r, h and porcine
363
(45)

caspase-1 p20 Antibody (D-4)

sc-398715mouse IgG2b κ259-294 (m)WB, IP, IF, IHC(P), ELISAm, r
119
(29)

caspase-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

caspase-1 Double Nickase Plasmid (m)

sc-419461-NICmGene KnockoutPuromycin0
(0)

caspase-1 Double Nickase Plasmid (m2)

sc-419461-NIC-2mGene KnockoutPuromycin0
(0)

caspase-1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

caspase-1 CRISPR Activation Plasmid (m)

sc-419461-ACTmGene ActivationPuro, Blast, Hygro0
(0)

caspase-1 CRISPR Activation Plasmid (m2)

sc-419461-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

caspase-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

caspase-1 siRNA (h)

sc-29235hGene SilencingN/A
10
(0)

caspase-1 siRNA (h2)

sc-156046hGene SilencingN/A0
(0)

caspase-1 shRNA Plasmid (h)

sc-29235-SHhGene SilencingPuromycin
10
(0)

caspase-1 shRNA Plasmid (h2)

sc-156046-SHhGene SilencingPuromycin0
(0)

caspase-1 shRNA (h) Lentiviral Particles

sc-29235-VhGene SilencingPuromycin
10
(0)

caspase-1 shRNA (h2) Lentiviral Particles

sc-156046-VhGene SilencingPuromycin0
(0)

caspase-1 (h)-PR

sc-29235-PRhPrimerN/A
10
(0)

caspase-1 siRNA (m)

sc-29922mGene SilencingN/A
3
(0)

caspase-1 shRNA Plasmid (m)

sc-29922-SHmGene SilencingPuromycin
3
(0)

caspase-1 shRNA (m) Lentiviral Particles

sc-29922-VmGene SilencingPuromycin
3
(0)

caspase-1 (m)-PR

sc-29922-PRmPrimerN/A
3
(0)

caspase-1 siRNA (r)

sc-61878rGene SilencingN/A
3
(0)