caspase-12 Antibodies

Santa Cruz Biotechnology provides a broad selection of caspase-12 monoclonal antibodies for research in apoptosis and cellular signaling pathways. Caspase-12 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Caspase-12 plays a critical role in the intrinsic apoptotic pathway, particularly in response to endoplasmic reticulum stress. The protein activates downstream effector caspases, leading to programmed cell death, which is essential for maintaining cellular homeostasis and preventing disease progression. Understanding caspase-12 function is vital for elucidating mechanisms of neurodegeneration and other pathologies associated with dysregulated apoptosis. Researchers worldwide utilize caspase-12 monoclonal antibodies to investigate cellular processes and disease mechanisms. Advanced detection methods, including horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC) conjugates, enable precise visualization of caspase-12 in experimental settings. The exceptional specificity of Santa Cruz Biotechnology monoclonal antibodies for caspase-12 continues to advance scientific understanding of cellular death pathways and their implications in human health and disease.