caspase-8 Substrates
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ac-DEVD-AFC | 201608-14-2 | sc-311274 sc-311274A | 1 mg 5 mg | $65.00 $200.00 | 13 | |
Ac-DEVD-AFC is a fluorogenic substrate specifically designed for caspase-8, showcasing unique interactions that facilitate its cleavage. The substrate's structure allows for efficient binding to the active site, promoting rapid hydrolysis and fluorescence emission upon enzymatic action. Its kinetic profile reveals a high turnover rate, making it an effective probe for monitoring caspase-8 activity. The substrate's design enhances specificity, minimizing cross-reactivity with other caspases, thus ensuring accurate assessment of apoptotic processes. | ||||||
Ac-DEVD-pNA | 189950-66-1 | sc-311275 sc-311275A sc-311275B sc-311275C | 1 mg 5 mg 25 mg 250 mg | $97.00 $286.00 $734.00 $4692.00 | 14 | |
Ac-DEVD-pNA is a synthetic substrate tailored for caspase-8, characterized by its ability to undergo specific proteolytic cleavage. The p-nitroaniline moiety provides a distinct chromogenic signal upon enzymatic action, allowing for sensitive detection. Its structural configuration promotes optimal interaction with the caspase-8 active site, resulting in a defined reaction kinetics profile. This substrate exhibits minimal interference from other proteases, ensuring precise measurement of caspase-8 activity in apoptotic pathways. | ||||||
Ac-IETD-AFC | 211990-57-7 | sc-311276 sc-311276A | 5 mg 10 mg | $281.00 $453.00 | 1 | |
Ac-IETD-AFC is a synthetic substrate designed for caspase-8, featuring a unique fluorogenic component that emits fluorescence upon cleavage. This substrate's structure enhances binding affinity to the caspase-8 active site, facilitating rapid reaction kinetics. The specific interactions between Ac-IETD-AFC and caspase-8 allow for selective detection, minimizing cross-reactivity with other caspases. Its sensitivity to enzymatic activity makes it a powerful tool for studying apoptotic signaling pathways. | ||||||
Z-DEVD-AFC | sc-296746 sc-296746A | 5 mg 50 mg | $151.00 $1358.00 | 1 | ||
Z-DEVD-AFC is a specialized fluorogenic substrate tailored for caspase-8, characterized by its unique peptide sequence that promotes selective cleavage. The substrate's design incorporates a fluorophore that emits a distinct signal upon enzymatic action, enabling real-time monitoring of caspase-8 activity. Its structural features optimize interaction with the enzyme's active site, ensuring high specificity and efficient reaction rates, making it ideal for dissecting apoptotic mechanisms. | ||||||