Date published: 2026-4-24

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14-3-3 Antibodies

Santa Cruz Biotechnology features a diverse variety of 14-3-3 monoclonal antibodies for research focused on understanding cellular processes. 14-3-3 Antibodies are applicable in various techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). 14-3-3 proteins are essential regulatory molecules that interact with a variety of signaling proteins, influencing processes such as cell cycle regulation, apoptosis, and signal transduction. The ability of 14-3-3 proteins to bind to phosphorylated serine and threonine residues allows for modulation of target protein activity, making 14-3-3 proteins crucial in maintaining cellular homeostasis and responding to stress. Due to involvement in numerous signaling pathways, 14-3-3 proteins are implicated in various diseases, including cancer and neurodegenerative disorders. Researchers studying 14-3-3 proteins can explore their functions in cell signaling, protein-protein interactions, and disease mechanisms. Understanding 14-3-3 protein regulation and function is vital for developing therapeutic strategies for various pathological conditions. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific knowledge of 14-3-3 proteins and their impact on human health.

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14-3-3 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

14-3-3 β Antibody (A-6)

sc-25276mouse IgG2b κ225-244 (h)WB, IP, IF, IHC(P), ELISAm, r, h
43
(14)

14-3-3 ε Antibody (8C3)

sc-23957mouse IgG2a κ136-152 (ovine)WB, IP, IF, IHC(P)m, r, h and ovine
52
(16)

14-3-3 ε Antibody (F-3)

sc-393177mouse IgG1 κ136-175 (h)WB, IP, IF, IHC(P), ELISAm, r, h
8
(3)

14-3-3 η Antibody (6A12)

sc-293464mouse IgG2a κ71-170 (h)WB, IP, ELISAm, r, h
2
(2)

14-3-3 γ Antibody (D-6)

sc-398423mouse IgG1 κ128-149 (h)WB, IP, IF, ELISAm, r, h
10
(4)

14-3-3 γ Antibody (6A1)

sc-69955mouse IgG2aN-Terminal (h)WB, IPm, r, h
4
(3)

14-3-3 γ Antibody (KC21)

sc-59421mouse IgG2aN-Terminal (h)WB, IPm, r, h
1
(1)

14-3-3 σ Antibody (E-11)

sc-166473mouse IgG3 κN-terminal (h)WB, IP, IF, IHC(P), ELISAm, r, h
11
(8)

14-3-3 σ Antibody (5D7)

sc-100638mouse IgG1 κ1-249 (h)WB, IP, IF, IHC(P), ELISAh
30
(7)

14-3-3 θ Antibody (5J20)

sc-69720mouse IgG1 κFL (h)WB, IP, IF, IHC(P), FCM, ELISAm, r, h
6
(3)

14-3-3 θ Antibody (3B9)

sc-59414mouse IgG1 κFL (h)WB, IP, IF, IHC(P), FCM, ELISAm, r, h
7
(4)

14-3-3 ζ Antibody (1B3)

sc-293415mouse IgG1 κ51-150 (h)WB, IP, ELISAm, r, h
13
(6)

14-3-3 ζ Antibody (G-2)

sc-518031mouse IgG3 κ122-140 (h)WB, IP, IF, ELISAm, r, h
3
(1)

pan 14-3-3 Antibody (B-8)

sc-133233mouse IgG1 κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
14
(12)

pan 14-3-3 Antibody (H-8)

sc-1657mouse IgG2b κ1-30 (h)WB, IP, IF, IHC(P), FCM, ELISAm, r, h
236
(16)

pan 14-3-3 Antibody (B-11)

sc-133232mouse IgG1 κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
11
(4)

pan 14-3-3 Antibody (F-1)

sc-166061mouse IgG2b κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(2)

14-3-3 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

14-3-3 ε CRISPR/Cas9 KO Plasmid (h)

sc-400998hGene KnockoutGFP0
(0)

14-3-3 ε HDR Plasmid (h)

sc-400998-HDRhHomology Directed RepairPuromycin0
(0)

14-3-3 η Double Nickase Plasmid (h)

sc-402892-NIChGene KnockoutPuromycin0
(0)

14-3-3 γ CRISPR/Cas9 KO Plasmid (h)

sc-401063hGene KnockoutGFP0
(0)

14-3-3 γ HDR Plasmid (h)

sc-401063-HDRhHomology Directed RepairPuromycin0
(0)

14-3-3 σ CRISPR/Cas9 KO Plasmid (h2)

sc-401096-KO-2hGene KnockoutGFP0
(0)

14-3-3 σ HDR Plasmid (h2)

sc-401096-HDR-2hHomology Directed RepairPuromycin0
(0)

14-3-3 σ Double Nickase Plasmid (h)

sc-401096-NIChGene KnockoutPuromycin0
(0)

14-3-3 σ Double Nickase Plasmid (h2)

sc-401096-NIC-2hGene KnockoutPuromycin0
(0)

14-3-3 θ CRISPR/Cas9 KO Plasmid (h)

sc-401384hGene KnockoutGFP0
(0)

14-3-3 θ HDR Plasmid (h)

sc-401384-HDRhHomology Directed RepairPuromycin0
(0)

14-3-3 ζ CRISPR/Cas9 KO Plasmid (h)

sc-400490hGene KnockoutGFP
1
(1)

14-3-3 ζ HDR Plasmid (h)

sc-400490-HDRhHomology Directed RepairPuromycin
1
(1)

14-3-3 ζ Double Nickase Plasmid (h)

sc-400490-NIChGene KnockoutPuromycin
1
(1)

14-3-3 ζ Double Nickase Plasmid (h2)

sc-400490-NIC-2hGene KnockoutPuromycin
1
(1)

14-3-3 ζ CRISPR/Cas9 KO Plasmid (m)

sc-423751mGene KnockoutGFP0
(0)

14-3-3 ζ HDR Plasmid (m)

sc-423751-HDRmHomology Directed RepairPuromycin0
(0)

14-3-3 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

14-3-3 ε CRISPR Activation Plasmid (h)

sc-400998-ACThGene ActivationPuro, Blast, Hygro0
(0)

14-3-3 η CRISPR Activation Plasmid (h)

sc-402892-ACThGene ActivationPuro, Blast, Hygro0
(0)

14-3-3 η CRISPR Activation Plasmid (h2)

sc-402892-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

14-3-3 η CRISPR Activation Plasmid (m)

sc-423749-ACTmGene ActivationPuro, Blast, Hygro0
(0)

14-3-3 γ CRISPR Activation Plasmid (h)

sc-401063-ACThGene ActivationPuro, Blast, Hygro0
(0)

14-3-3 σ CRISPR Activation Plasmid (h)

sc-401096-ACThGene ActivationPuro, Blast, Hygro0
(0)

14-3-3 θ CRISPR Activation Plasmid (h)

sc-401384-ACThGene ActivationPuro, Blast, Hygro0
(0)

14-3-3 θ CRISPR Activation Plasmid (h2)

sc-401384-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

14-3-3 ζ CRISPR Activation Plasmid (h)

sc-400490-ACThGene ActivationPuro, Blast, Hygro
1
(1)

14-3-3 ζ Lentiviral Activation Particles (h)

sc-400490-LAChGene ActivationPuro, Blast, Hygro
1
(1)

14-3-3 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

14-3-3 β siRNA (h)

sc-29186hGene SilencingN/A
5
(0)

14-3-3 β shRNA Plasmid (h)

sc-29186-SHhGene SilencingPuromycin
5
(0)

14-3-3 β shRNA (h) Lentiviral Particles

sc-29186-VhGene SilencingPuromycin
5
(0)

14-3-3 β siRNA (m)

sc-29187mGene SilencingN/A0
(0)

14-3-3 β shRNA Plasmid (m)

sc-29187-SHmGene SilencingPuromycin0
(0)

14-3-3 β shRNA (m) Lentiviral Particles

sc-29187-VmGene SilencingPuromycin0
(0)

14-3-3 β siRNA (r)

sc-270534rGene SilencingN/A0
(0)

14-3-3 β shRNA Plasmid (r)

sc-270534-SHrGene SilencingPuromycin0
(0)

14-3-3 β shRNA (r) Lentiviral Particles

sc-270534-VrGene SilencingPuromycin0
(0)

14-3-3 ε siRNA (h)

sc-29588hGene SilencingN/A
11
(0)

14-3-3 ε shRNA Plasmid (h)

sc-29588-SHhGene SilencingPuromycin
11
(0)

14-3-3 ε shRNA (h) Lentiviral Particles

sc-29588-VhGene SilencingPuromycin
11
(0)

14-3-3 ε siRNA (m)

sc-29589mGene SilencingN/A
2
(0)

14-3-3 ε shRNA Plasmid (m)

sc-29589-SHmGene SilencingPuromycin
2
(0)

14-3-3 ε shRNA (m) Lentiviral Particles

sc-29589-VmGene SilencingPuromycin
2
(0)

14-3-3 ε siRNA (r)

sc-270535rGene SilencingN/A0
(0)

14-3-3 ε shRNA Plasmid (r)

sc-270535-SHrGene SilencingPuromycin0
(0)

14-3-3 ε shRNA (r) Lentiviral Particles

sc-270535-VrGene SilencingPuromycin0
(0)

14-3-3 η siRNA (h)

sc-43581hGene SilencingN/A
4
(0)

14-3-3 η shRNA Plasmid (h)

sc-43581-SHhGene SilencingPuromycin
4
(0)

14-3-3 η shRNA (h) Lentiviral Particles

sc-43581-VhGene SilencingPuromycin
4
(0)

14-3-3 η siRNA (m)

sc-43582mGene SilencingN/A
2
(0)

14-3-3 η shRNA Plasmid (m)

sc-43582-SHmGene SilencingPuromycin
2
(0)

14-3-3 η shRNA (m) Lentiviral Particles

sc-43582-VmGene SilencingPuromycin
2
(0)

14-3-3 η siRNA (r)

sc-270541rGene SilencingN/A0
(0)

14-3-3 η shRNA Plasmid (r)

sc-270541-SHrGene SilencingPuromycin0
(0)

14-3-3 η shRNA (r) Lentiviral Particles

sc-270541-VrGene SilencingPuromycin0
(0)

14-3-3 γ siRNA (h)

sc-29582hGene SilencingN/A
4
(0)

14-3-3 γ siRNA (h2)

sc-44279hGene SilencingN/A0
(0)

14-3-3 γ shRNA Plasmid (h)

sc-29582-SHhGene SilencingPuromycin
4
(0)

14-3-3 γ shRNA Plasmid (h2)

sc-44279-SHhGene SilencingPuromycin0
(0)

14-3-3 γ shRNA (h) Lentiviral Particles

sc-29582-VhGene SilencingPuromycin
4
(0)

14-3-3 γ shRNA (h2) Lentiviral Particles

sc-44279-VhGene SilencingPuromycin0
(0)

14-3-3 γ siRNA (m)

sc-29584mGene SilencingN/A
1
(0)

14-3-3 γ shRNA Plasmid (m)

sc-29584-SHmGene SilencingPuromycin
1
(0)

14-3-3 γ shRNA (m) Lentiviral Particles

sc-29584-VmGene SilencingPuromycin
1
(0)

14-3-3 γ siRNA (r)

sc-156018rGene SilencingN/A0
(0)

14-3-3 γ shRNA Plasmid (r)

sc-156018-SHrGene SilencingPuromycin0
(0)

14-3-3 γ shRNA (r) Lentiviral Particles

sc-156018-VrGene SilencingPuromycin0
(0)

14-3-3 σ siRNA (h)

sc-29590hGene SilencingN/A
9
(0)

14-3-3 σ shRNA Plasmid (h)

sc-29590-SHhGene SilencingPuromycin
9
(0)

14-3-3 σ shRNA (h) Lentiviral Particles

sc-29590-VhGene SilencingPuromycin
9
(0)

14-3-3 σ siRNA (m)

sc-29591mGene SilencingN/A
3
(0)

14-3-3 σ shRNA Plasmid (m)

sc-29591-SHmGene SilencingPuromycin
3
(0)

14-3-3 σ shRNA (m) Lentiviral Particles

sc-29591-VmGene SilencingPuromycin
3
(0)

14-3-3 θ siRNA (h)

sc-29586hGene SilencingN/A
5
(0)

14-3-3 θ shRNA Plasmid (h)

sc-29586-SHhGene SilencingPuromycin
5
(0)

14-3-3 θ shRNA (h) Lentiviral Particles

sc-29586-VhGene SilencingPuromycin
5
(0)

14-3-3 θ siRNA (m)

sc-29587mGene SilencingN/A0
(0)

14-3-3 θ shRNA Plasmid (m)

sc-29587-SHmGene SilencingPuromycin0
(0)

14-3-3 θ shRNA (m) Lentiviral Particles

sc-29587-VmGene SilencingPuromycin0
(0)

14-3-3 θ siRNA (r)

sc-270533rGene SilencingN/A0
(0)

14-3-3 θ shRNA Plasmid (r)

sc-270533-SHrGene SilencingPuromycin0
(0)

14-3-3 θ shRNA (r) Lentiviral Particles

sc-270533-VrGene SilencingPuromycin0
(0)

14-3-3 ζ siRNA (h)

sc-29583hGene SilencingN/A
11
(0)

14-3-3 ζ shRNA Plasmid (h)

sc-29583-SHhGene SilencingPuromycin
11
(0)

14-3-3 ζ shRNA (h) Lentiviral Particles

sc-29583-VhGene SilencingPuromycin
11
(0)

14-3-3 ζ siRNA (m)

sc-29585mGene SilencingN/A
4
(0)

14-3-3 ζ shRNA Plasmid (m)

sc-29585-SHmGene SilencingPuromycin
4
(0)

14-3-3 ζ shRNA (m) Lentiviral Particles

sc-29585-VmGene SilencingPuromycin
4
(0)

14-3-3 ζ siRNA (r)

sc-156019rGene SilencingN/A
1
(0)

14-3-3 ζ shRNA Plasmid (r)

sc-156019-SHrGene SilencingPuromycin
1
(0)

14-3-3 ζ shRNA (r) Lentiviral Particles

sc-156019-VrGene SilencingPuromycin
1
(0)

14-3-3 Transfected Lysates

Empty Table HeaderProduct NameCATALOG #SpeciesCONTROL ANTIBODYCitationsRATING

14-3-3 ζ (h): 293T Lysate

sc-111414h0
(0)

14-3-3 ζ (h6): 293 Lysate

sc-175740h60
(0)